β-Nicotinamide mononucleotide (NMN), molecular formula is C11H15N2O8P, CAS number is 1094-61-7, relative molecular weight 334.22, a naturally occurring bioactive nucleotide, a precursor substance of a key coenzyme nicotinamide adenine dinucleotide (NAD+) in mammals, the main function is reflected by NAD+, participating in coenzyme I, human metabolic function, cell senescence, gene expression, immune function and many other key processes, in aging, At the forefront of health and disease research, it is a precious raw material for the pharmaceutical, functional food, cosmetics and other industries.
β-Nicotinamide mononucleotide (NMN) has the properties of high polarity, non-volatile, intramolecular salting, soluble in water, and insoluble in organic solvents, which restricts the application of many conventional quantitative analysis methods. Common quantitative detection methods in laboratories include liquid chromatography (HPLC), liquid chromatography-mass spectrometry (HPLC-MS), nuclear magnetic resonance spectroscopy (NMR), etc. Considering the sensitivity and detection cost, the reference standard used laboratory liquid chromatography to detect the NMN content.
Optimizing the chromatographic conditions, measuring the NMN standard working solution, plotting the standard curve regression equation, calculating the linear range, correlation coefficient, etc., the detection method has good reproducibility and method precision, and can be used for the determination of NMN content in samples. The method of detecting β-nicotinamide mononucleotide (NMN) by high-performance chromatography is simple and time-consuming, which improves the efficiency of analysis and detection.
The detection of β-nicotinamide mononucleotide (NMN) content is of multifaceted significance in biological research, health care product development and other fields, helping manufacturers optimize production processes, ensuring product stability and effectiveness, and providing support for research and practice in related fields. Although up to now, it has not obtained the license of drugs, health foods, food additives and new food raw materials in the mainland, NMN, as an anti-aging star product, undoubtedly has a broad market growth space.
The chemical synthesis method of NMN has been gradually improved, and the production technology has also matured, and the microsource testing laboratory can use classical high-performance liquid chromatography to compare with standards to achieve quantitative and qualitative analysis of nicotinamide mononucleotide. Self-built laboratories with various types of instruments and equipment such as liquid chromatography-mass spectrometry and high-resolution liquid quality can quickly respond to testing needs, formulate and develop testing processes based on sample conditions and testing requirements, and provide you with efficient and accurate testing technical services. If you have similar testing needs, please call the laboratory for consultation!
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