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The National Health Commission exposed 10 cases of medical paper fraud and scientific research untrustworthiness and severely punished the personnel involved

author:Overseas network

Source: People's Daily News

People's Daily Beijing, August 19 (Reporter Cui Yuanyuan) Today, the official website of the National Health and Health Commission announced the results of the investigation and handling of medical research integrity cases in some institutions, and severely punished the falsification and untrustworthy behavior of medical institution personnel such as piecing and tampering with the data and pictures of the papers, writing on behalf of third parties, purchasing experimental data, and buying and selling papers.

Case 1

Wang Xiaozhen of Xingtai People's Hospital of Hebei Province is the corresponding author, and Xie Jin is the first author of the paper "MiR-221inhibitsproliferationofpancreaticcancercellsviadownregulationofSOS3", after investigation, the project did not complete the experiment, and the paper data and pictures were patched together, tampered with and other falsifications.

In this regard, Xingtai People's Hospital made the following treatment of the relevant responsible personnel:

1. Conduct scientific research integrity admonition talks and criticism education for all parties, and inform and criticize all parties within a certain range;

2. The paper has been reimbursed for the layout fee and the SCI paper award has been fully recovered;

3. Revoke the 2019 Hebei Medical Science and Technology Progress Award that has been obtained;

4. Suspend the first author's scientific research project declaration, project establishment, appraisal, professional title promotion and other activities for five years, and cancel the first author's qualifications as a nominator or recommender, a nominated or recommended person, a review expert, etc.;

5. Suspend the declaration, establishment, evaluation and promotion of scientific research projects by corresponding authors and other authors in the research group for one year.

Case 2

Jilin Province Jilin Central Hospital Liu Bo published a paper for the corresponding author "Astragaloside IVprotectsATDC5cellsfromlipopolilysaccharide-causeddamagethroughregulatingmiR-203/MyD88", after investigation, the paper was written by Liu Bo through a third-party intermediary agency entrusted by others, and did not inform other authors before submission, Involving improper signatures, it is a paper fraud and scientific research untrustworthy behavior.

In this regard, Jilin Central Hospital gave Liu Bo the following sanctions: cancel the promotion title within four years, declare financial support projects, and declare the qualifications of provincial and municipal science and technology progress awards after the research projects pass the acceptance.

Case 3

The paper "RegulationofmTORbymiR-107tofacilitategliomacellapoptosisandtoenhancecisplatinsensitivity" published by Song Shuqing of Daqing People's Hospital of Heilongjiang Province as the corresponding author and Su Pengfei as the first author" was written and distributed by an intermediary.

In this regard, Daqing People's Hospital determined that Su Pengfei was mainly responsible, Xu Yueyue was secondarily responsible, and Song Shuqing was generally responsible. The relevant responsible persons are to make the following handling opinions:

1. Give Su Pengfei: scientific research integrity admonition talk; cancel the application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent titles and other qualifications within five years; cancel the qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. within five years; request retraction.

2. Give Xu Yueyue: scientific research integrity admonition talk; cancel the application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent titles and other qualifications within five years; terminate all scientific research projects in research.

3. Give Song Shuqing admonition talk on scientific research integrity.

Case 4

Heilongjiang Provincial Hospital Cui Rong as the corresponding author, Zhang Shu as the first author published the paper "ThetargetregulationofMiR-26aonPTEN-PI3K/AKTsignalingpathwayinmyocardialfibrosisaftermyocardialinfarction", after investigation, it was funded by Cui Rong and Zhang Shu to ask others to write papers on behalf of others, and there was academic misconduct.

In this regard, Heilongjiang Provincial Hospital has made the following treatment of the relevant responsible personnel:

1. Cui Rong shall be given the following sanctions: revoke the title of chief physician obtained by applying the paper, and report to the title approval management department for revocation; withdraw the bonus obtained by applying the paper; cancel the qualification to undertake financial support projects within five years; conduct scientific research integrity and sincere talks; and give a warning sanction according to Article 20 of the Interim Provisions on the Punishment of Public Institution Staff.

2. Zhang Shu will be given the following sanctions: cancel the qualification to declare the title of deputy chief physician in 2020; withdraw the bonus obtained by applying the paper; cancel the qualification to undertake financial support projects within five years; conduct scientific research integrity and sincere talks; and give a warning sanction according to Article 20 of the Interim Provisions on the Punishment of Public Institution Staff.

Case Five

Sun Jinliang, The First People's Hospital of Changzhou City, Jiangsu Province, as the first author and corresponding author, published the paper "Protectivefunctionsof?myricetininLPS-inducedcardiomyocytes H9c2cellsinjurybyregulationof?" MALAT1", after investigation, is a third-party ghostwriting proxy, which is a serious academic misconduct.

In this regard, the First People's Hospital of Changzhou City gave Sun Jinliang the following treatment: a serious warning punishment within the party; the withdrawal of the above-mentioned papers published; the cancellation of the declaration of qualifications for various scientific research projects and scientific and technological achievements at all levels for five years; the suspension of incentive performance wages for twelve months; and the cancellation of a senior appointment qualification.

Case VI

Du Fangchao, a former employee of the First People's Hospital of Hefei City, Anhui Province, published the paper "ExpressionofmiR-141andYAP1ingastriccarcinomaandmodulationofcancercellproliferationandapoptosis" published as the first author, which was investigated as an academic misconduct of purchasing experimental data and writing and distributing scientific research papers on behalf of others.

After coordination, Du Fangchao's working unit will make the following treatment of Du Fangchao:

Du Fangchao's qualifications for promotion to job titles and declaration of scientific and technological plans (special projects, funds, etc.) projects for five years are cancelled, and at the same time, they are recorded in the scientific research integrity information system, and administrative demotion is given (from attending physician to physician).

Case SEVEN

Papers published by Liu Yuxia of Zhoukou Central Hospital of Henan Province as corresponding author/first author, and Zhang Yan of Huaihe Hospital of Henan University as the second author" Lyciumbarbarumpolysaccharidesalleviatehydrogenperoxide-inducedinjurybyup-regulationofmiR-4295inhumantrabecularmeshworkcells", Chinese title "Goji polysaccharides reduce the damage of peroxide to human trabecular cells by up-regulating miR-4295", after investigation, The department writes papers on behalf of the relevant responsible persons and carries out the following treatment:

1. For the corresponding author/first author Liu Yuxia: immediately conduct a good faith admonition talk; give the whole hospital notice criticism; require the paper to be withdrawn, cancel all benefits and honors related to the paper; and not declare scientific and technological plans, scientific and technological awards, and scientific and technological talents within five years.

2. To the second author, Zhang Yan: Notify the unit where you are located; ask the unit to immediately conduct a conversation of integrity admonition.

Case VIII

The paper "MiR-20aregulatesfibroblast-likesynoviocyteproliferation?and?apoptosis?in?rheumatoid?arthritis" published by Lu Wenzhong of Baise People's Hospital of Guangxi Zhuang Autonomous Region as the corresponding author and Wei Xijiang as the first author, is the first author Wei Xijiang alone contacted a third-party intermediary agency to buy. Academic misconduct such as buying and selling papers is primarily responsible.

In this regard, Baise People's Hospital made the following treatment for the relevant responsible personnel:

1. For the first author, Wei Xijiang: order him to revoke the paper; order him to return the paper awards he has received; cancel the extra points for the evaluation of medical ethics and medical style in 2017 and 2018; order him to make detailed written explanations and reviews; recommend that he revoke the deputy senior professional and technical qualifications obtained in 2018; and not declare scientific research projects, scientific research funds, awards, honors, job titles, etc. at all levels within five years.

2. For Lu Wenzhong (corresponding author), Li Xinwu (second author), Lu Jili (third author), and Liang Junqing (fifth author): Cancel the extra points for the 2017 and 2018 medical ethics and medical style evaluations; give warnings and scientific research integrity admonitions, and deal with them according to improper signatures, and must not declare scientific research projects, scientific research funds, awards, honors, job titles, etc. at all levels within one year.

3. For Wei Shangbing (sixth author): Give a warning and admonition of scientific research integrity, and deal with it according to improper signature, and shall not declare scientific research projects at all levels, scientific research funds, awards, honors, job titles, etc. within one year.

Case Nine

The paper "MiR-17RegulatesProstateCancerCellProliferationand ApoptosisThroughInhibitingJAK-STAT3Signaling" published by Dai Hong of the Three Gorges Hospital Affiliated to Chongqing University was fully commissioned by Dr. Dai Hong.

In this regard, the Three Gorges Hospital affiliated to Chongqing University has made the following treatment of the relevant responsible personnel:

1. Give Dai Hong: scientific research integrity admonition talk; the hospital publicly notified criticism and demerit punishment; cancelled his medical technology level 6 post title to the original level 7 post; cancelled the qualification to undertake financial support projects within five years; returned the hospital award paper bonus within 30 days; independently contacted the magazine within 30 days to withdraw the paper involved; and returned the second prize honor and bonus of the scientific research paper of the Wanzhou District Health System within 30 days.

2. Give Wang Chunmei, Yu Zhihai, He Donglin, Yu Kun, Liu Yin, Wang Sheng 6 participating authors: scientific research integrity admonition talk; the hospital publicly reported criticism.

Case 10

The paper "miR-132Regulates AdriamycinResistancein ColorrectalCancerCellsThroughTargetingExtracellularSignal-RegulatedKinase1" published by Zhang Mei of the Fourth People's Hospital of Shaanxi Province and Liu Yong of Yan'an People's Hospital was examined and was ghostwritten by a third party. The Fourth People's Hospital of Shaanxi Province made the following treatment of the relevant responsible person Zhang Mei: conducting a talk on scientific research integrity; warning punishment in the hospital, and the whole hospital notified criticism; canceling the qualifications for promotion titles within six years and declaring the qualifications for various scientific research projects; revoking the awards awarded by the papers, recovering the bonuses; and ordering the withdrawal of the manuscript.

In this regard, Yan'an Municipal People's Hospital made the following treatment of the relevant responsible person Liu Yong:

Conduct scientific research integrity admonition talks; written inspections, the whole hospital to circulate criticism; revoke the awards; cancel the declaration of various national, provincial and municipal projects within six years, reward declarations, and promotion of professional title qualifications.