Health food is a food that claims to have specific health functions or is intended to supplement vitamins and minerals. That is, food suitable for consumption by specific groups of people, has the function of regulating the body, is not intended to treat diseases, and does not produce any acute, subacute or chronic harm to the human body. In the previous article, Cheng Cheng Xiaobian briefly introduced the requirements and specifications of the functional evaluation of health food to everyone, and today to enhance the immune function of health food as an example and then let you understand it together!
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weight
Organ/weight ratio measurement: thymus/weight ratio, spleen/weight ratio
Cellular immunofunction assays: mouse splenocyte transformation experiments, delayed-onset allergy experiments
Humoral immunofunction assays: antibody-producing cell testing, serum hemolysin assays
Mononuclear-macrophage function assay: mouse carbon clearance experiment, mouse intraperitoneal macrophage engulfing chicken red blood cell experiment
NK cell viability assay
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The indicators listed are mandatory items
Tests were performed using normal or immunocompromised model animals
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Determination of enhanced immune function: Positive results in any two aspects of cellular immune function, humoral immune function, monocyte-macrophage function, and NK cell activity can be determined to have enhanced immunity function of the subject sample.
Among them, the results of two experiments in the cellular immunofunction assay project are positive, or the results of the two dose groups of either experiment are positive, which can determine the positive results of the cellular immune function assay. Both tests in the humoral immunofunction assay project are positive, or the results of both dose groups in either experiment are positive, which can determine the positive results of humoral immunofunction. Both tests in the mononucleus-macrophage function assay project were positive, or both dose groups in either experiment were positive, which determined that the monocyte-macrophage function results were positive. NK cell activity assay experiments can be determined to have positive results in more than one dose group of NK cell activity assay experiments.
Cheng Cheng Xiaobian Conclusion: Taking the enhancement of immune function as an example, the experiment has a rigorous experimental process and judgment basis, and the experimental object is animal experiment. However, it is not limited to animals, such as hypoglycemic experiments and hypolipidemic experiments require the participation of human experiments, that is, after taking health care products for a certain period of time, the human blood glucose/blood lipids are measured. For experiments that are harmful or invasive to the human body, animals are required to complete the test and determine the judgment.