Thrombotic superficial phlebitis is a clinically common peripheral vascular disease, in which thrombotic and inflammatory lesions occur in the superficial veins of the trunk or limb, with acute onset, redness, burning, swelling of the skin along the superficial vein circulation, and the appearance of nodules or cords, accompanied by obvious pain.
When the disease is prolonged into the chronic stage, the cord gradually hardens, the limbs appear numb, swollen, especially after a long time, inflammation invades the saphenous vein of the lower limbs, accounting for 80%-90% of the total incidence, the disease does not get worse and leads to deep vein thrombosis, and even the occurrence of pulmonary embolism and life-threatening.
At present, clinically, anti-infection, anti-platelet aggregation, thrombolytic and other drugs are mainly used for thrombotic superficial phlebitis of the lower limbs, and then according to the disease classification of thrombotic superficial phlebitis, immunosuppressants, nonsteroidal analgesia and anti-inflammatory drugs are reasonably used, and surgical treatment is carried out for patients who meet the indications for surgery, but the overall efficacy is limited. Proprietary Chinese medicine Choriconoshu tong pills (granules) can effectively make up for the lack of Western medicine in this regard.
Compatibility analysis of Choricono Tung Pills
Choroid Shutong Pill is the experience of Tang Zuxuan, a master of traditional Chinese medicine, in the treatment of thrombotic superficial phlebitis of the lower extremities, the prescription Chinese medicine is composed of astragalus, honeysuckle, yellow cedar, Cangshu, coix kernel, Xuan Ginseng, angelica, white peony, leech, centipede, whole scorpion, and licorice. It has the function of straightening the network, clearing heat and detoxification, and dampening and dissolving stasis. It is indicated for thrombotic superficial phlebitis caused by damp and hot bruising, swelling, pain, dark redness of the skin, or cord-like substances in the lower extremities caused by non-acute deep vein thrombosis.
Through the analysis of the compatibility components, it can be seen that the vein Shutong Pill is composed of astragalus and angelica, the four mysterious Yong'an soups of honeysuckle, Xuan Ginseng, Angelica and Licorice, the ermiaos of Cangshu and Huang Cedar, the antispasmodic dispersion of the combination of centipedes and whole scorpions and the peony licorice soup, which is rich in the compatibility characteristics of the Chinese medicine treatment group, which cuts the basic disease mechanism of the disease's positive qi deficiency, damp and hot stasis and obstruction of the network. It is necessary to take care of both rectification and exorcism, and treat thrombotic superficial phlebitis of the lower extremities mixed with virtual reality.
Astragalus tonify qi to support poison and water, nourish blood and stagnate paralysis, for the essential medicine of tonic qi, honeysuckle taste sweet and cold, gongshan clear heat and detoxification, for the heat poison sore carbuncle essential medicine, two drugs are compatible, help the right does not leave evil, dispel evil does not hurt the right, a total of the king's medicine. Yellow cedar, Cang Shu, Coix Kernel clear heat dry wet spleen, spleen health to help transport, heat with water dispersion, water metabolism function is normal, damp heat from the lower scorched away; Xuan Ginseng clear hot cool blood, detoxification loose knots, angelica, white peony blood to slow and urgent pain relief, and in the astragalus tonic effect under the guidance of the role of blood activation, the above drugs are all the subject medicine.
The initial illness qi knot in the menstrual period, long into the blood into the network, the Eastern Han Dynasty famous doctor Zhang Zhongjing pioneered the insect search and elimination method, Ye Gui also proposed in the "Clinical Guide Medical Case" that insect drugs can be added when searching and removing the xuantong vein, leeches can be painfully discharged, salty can walk blood, into the liver menstrual blood, for the blood to break the blood, one by one, the product of stasis through the meridian, in order to play the work of invigorating the blood circulation, centipede, the whole scorpion scattered knot pain relief, wind and antispasmodic communication, 3 insect drugs are adjuvant. Licorice tonify the spleen and qi, reconcile various medicines, and make medicines.
Modern pharmacological studies of Choriconoside pills
Modern pharmacological studies have shown that the active ingredients of astragalus flavonoids and astragalus polysaccharides have antioxidant, anti-inflammatory, nerve protection, antiviral and other effects, which can reduce plasma fibrinogen content, antithrombosis, and improve red blood cell function. The organic acids of honeysuckle have improved hemodynamic properties, increased plasmin activity in plasma, promoted plasmolytic systems and thrombolytic effects. In addition, it also has a good anti-inflammatory effect in vivo and at home.
Angelica is a qi medicine in the blood, which has good blood circulation and has obvious analgesic effect, which can alleviate the pain and irritability caused by venous thrombosis in both lower limbs. Angelica and its component, sodium ferulate, can not only regulate the body's immune response and reduce the damage of inflammatory mediators to the function of the body's organs, but also can resist platelet aggregation and reduce blood viscosity, thus preventing thrombosis.
Berberine, the main alkaloid component of cork, has a pronounced anti-inflammatory effect. Cangshu can inhibit capillary permeability, improve immune function, stimulate the body to produce immune factors, and can resist tumors, analgesia and so on. White peony can significantly inhibit thrombosis and accelerate blood flow. Ginseng extract can reduce the content of a variety of inflammatory mediators, increase the concentration of the anti-inflammatory factor interleukin-10, has a good anti-inflammatory effect, in addition to anti-cancer, antibacterial, hypoglycemic. Total flavonoids of licorice leaves can prolong the time of carotid artery thrombosis, and can be anticoagulant and antithrombotic.
Whole scorpion can inhibit platelet aggregation, enhance fibrinolytic activity, and have obvious anti-arterial thrombosis effect. Leech saliva extract has the effect of thrombolysis and anti-platelet aggregation, and also has an anti-inflammatory and swelling effect, which can effectively reduce the swelling and pain of the legs of patients with phlebitis. Centipedes have anti-atherosclerotic and anticoagulant effects, and centipede plasmin has a thrombolytic effect inside and outside the body.
Clinical trial of Choriconolone Pills
Clinical trials have shown that chorosin pills combined with urokinase in the treatment of thrombotic superficial phlebitis of the lower extremities have obvious efficacy and high safety in improving the swelling, redness, pain and tendons and veins of the patient's affected limbs. The combination of choriostem pills and diosmin tablets for the treatment of deep vein thrombosis of the lower extremities was found to significantly reduce the level of inflammatory mediators, reduce thrombosis and reduce bleeding tendencies, and the safety of clinical treatment is high. Chorisoconitic pills combined with rivaroxaban in the treatment of deep vein thrombosis of the lower extremities can effectively reduce blood viscosity and inflammatory response, improve clinical symptoms of patients, improve clinical efficacy, and benefit the prognosis of patients.