The flu triggered thrombocytopenia, and the two-month-old baby was admitted to a care unit

Red Net Moment, January 20 (Correspondent Li Jia Zhu Wenqing) Recently, Zhang Jie (pseudonym), who lives in Tianxin District, found that her baby's face for more than two months had a small needle-like rash, and at first Zhang Jie thought it was a common infant eczema, which did not attract attention. Two days later, the baby began to cough, fever, rash is also more and more, gradually spread throughout the body, some parts even fused into a patch of petechiae, ecchymosis, Ms. Zhang realized that things are not good, urgently took the baby to Changsha Central Hospital (Changsha Central Hospital affiliated to the University of South China) pediatric infection department for treatment, and finally was diagnosed with severe immune thrombocytopenia caused by influenza B.

Peng Huiyun, attending physician of the Department of Pediatric Infections of Changsha Central Hospital (Changsha Central Hospital affiliated to the University of South China), inquired about the medical history in detail after receiving the consultation, and gave the baby a comprehensive examination, and found that the child was covered with needle-like rashes all over the body, and bruises were visible on the left waist and abdomen, right groin, thighs and ankles. She immediately considered that this was not "eczema" but purpura caused by extensive subcutaneous bleeding, so she gave the child an urgent blood routine, and sure enough, it was a critical value: "Platelets are only 2×109/L" (normal values 100-300×109/L). Due to the young age of the child and the existence of extensive subcutaneous bleeding, it is necessary to be vigilant against life-threatening intracranial hemorrhage and gastrointestinal bleeding, etc., Peng Huiyun immediately arranged a green channel into the children's intensive care unit for further diagnosis and treatment.

What is worrying is that within 2 hours after hospitalization, medical staff found that the child had gastrointestinal bleeding, and the relevant results of the tracing suggested that the influenza B virus antigen was positive, and the re-examination of platelets was still only 3×109/L, and the disease was clearly diagnosed as severe immune thrombocytopenia and influenza (type B). The top priority is to regulate immunity, hemostasis, and anti-influenza virus therapy. Fortunately, after rapid symptomatic treatment, the child's platelets rose steadily. Under the careful care of medical staff, the child did not develop secondary bleeding from serious and important organs, and the platelets returned to normal at about 48 hours.

Zhang Xiaofo, director of the Department of Pediatrics of Changsha Central Hospital (Changsha Central Hospital Affiliated to the University of South China), introduced: Immune thrombocytopenia is an acquired bleeding disease caused by abnormal autoimmune function, the main clinical features are thrombocytopenia, skin purpura and mucosal bleeding, and in severe cases, intracranial hemorrhage, visceral bleeding, sudden major bleeding, etc., which will be life-threatening. The cause of the disease is not yet clear, and various viral and bacterial infections can be induced, as well as after vaccination. In this case, the child was only two months old and was infected with influenza B virus when immunity was not fully developed, resulting in immunosuppression and causing severe immune thrombocytopenia, and in the early stages of the disease, the parents mistakenly treated the bleeding spots on the face as eczema, delaying treatment.

Zhang Xiaofo reminded that there is a clear difference between eczema and bleeding points caused by thrombocytopenia. The form of the rash caused by eczema is generally flaky, raised, accompanied by cortical hyperplasia, local itching, and poorly defined borders. With the development of the disease, the rash can slowly expand, the boundary point is clearer, and the bleeding point of the skin is generally smaller, mostly needle-like, existing in the deep layers of the skin and does not bulge on the surface of the skin. And the color looks a little dark, and it will slowly disappear over time, if the bleeding points persist or spread throughout the body. If the area increases, or even ecchymosis appears, it is necessary to be vigilant of the manifestations of purpura and need to go to the hospital in time.

"The symptoms of infant diseases are often atypical, such as finding that the child has a purple piece of blue on the body for unknown reasons, or is prone to nosebleeds, blood in the stool, and blood in the urine, the family can not take it lightly, go to the hospital in time to avoid delaying the condition due to temporary negligence." Zhang Xiaofo stressed.