Text/Figure Yangcheng Evening News all-media reporter Zhang Hua
Correspondent Zhou Mi Li Wen
On December 29, the National Children's Regional Medical Center (Zhongnan) and guangzhou Women and Children's Medical Center held the unveiling ceremony of the fully automated sample bank of clinical biological resources (hereinafter referred to as the sample bank), and the ultra-low temperature automatic storage system of the sample bank was officially put into use. It is reported that this is the first set of automation libraries in the country to use special motors to achieve -80 °C storage, pipe picking and temporary storage in the whole region, and it is also the first set of automated libraries in china to achieve more than one million samples that have been running in the library, which is of great significance to medical scientific research and exploration.
Pi Lei, chief technician of the Clinical Biological Resource Library, introduced the application of the sample library
Invest 40 million yuan to build an automated biological resource library
On the negative ground floor of the Guangzhou Women and Children's Medical Center, an ultra-low temperature automated biological sample storage system is running. The reporter saw at the scene that a robot took a box of tissue samples from the deep and low temperature automatic storage system of minus 196 degrees and sent them into another system for picking pipes.
Pi Lei, chief technician of the clinical biological resource library, introduced: "The Municipal Women's and Children's Center established the clinical biological resource library in 2015, and so far the clinical sample collection department covers all specialties in the five hospitals, including 29 major disease cohorts and 32 common disease cohorts. Specimen types include peripheral blood, stool, other body fluids, throat swabs, fresh tissue, and tissue wax patches. The total number of incoming samples is 2.2 million, and the outbound samples are 70,000. Currently, more than 90% of the biological specimens here are blood. ”
According to the reporter's understanding, the city's women and children invested a total of 40 million yuan to build the project. "From the beginning of 2019, it took more than two years to complete." Gu Xiaoqiong, director of the clinical biological resource library, told reporters, "This storage center is composed of an ultra-low temperature automated storage system of minus 80 degrees of 5 million comprehensive stocks and an automated storage system of minus 196 degrees of deep and low temperature of 100,000 comprehensive stocks. At the same time, a special queue number is established for each specimen, which helps interdisciplinary and cross-ward outpatient clinics to work closely together and share resources. ”
The robot takes a box of tissue samples from an automated storage system at a deep temperature of minus 196 degrees
The specimen library ultimately serves scientific research and clinical services
As the largest women's and children's specialized hospital in central and southern China, it has about 3.53 million outpatient emergency visits and nearly 119,400 discharged patients in 2020, with rich clinical resources. Gong Sitang, deputy secretary of the party committee of Guangzhou Women and Children's Medical Center, said, "In order to solve clinical problems, we must do some scientific research. The reason is very simple, taking gastroenterology as an example, for example, there are more children with diarrhea this year, and most of them are norovirus infections, and we have stored stool samples from children. Five years later, there is another large-scale childhood diarrhea, so whether the current virus is the same as before, whether there is a mutation, at this time it is necessary to control the specimens, so as to grasp the occurrence and development of the virus, and find a way to deal with it in time. For example, the efficacy of the same drug in different patients is different, may be different from the patient's genetic inheritance, and the disease itself in each person's difference, through the comparison of specimens, we can find the most effective drug to implement precision treatment. ”
Gong Sitang also introduced that at present, during the construction of the clinical biological resource library, the gastroenterology and pediatric surgery experts of the Municipal Women's and Children's Center have applied these specimens to carry out scientific research such as biliary atresia and megacolon, and their results have been published in the Cell (Cell journal, the journal of the latest research findings in the field of life sciences issued by Cell Press) in 2019 and 2020.
The staff demonstrates the stored samples
At present, all general hospitals pay more and more attention to and emphasize the integration of scientific research and clinical work of hospitals. It is reported that at present, the Municipal Women's and Children's Center has grasped clinical and scientific research on the other in recent years. "At present, the center is building and improving the animal experiment platform, molecular diagnosis platform, infection research platform, birth defect platform, brain science platform, etc." Gong Sitang said, "The development of medical scientific research should come from clinical practice, and problems should be found, raised, researched and solved in clinical practice." Medical scientific research provides knowledge, theories and means for clinical medical treatment, provides technical support for solving clinical problems, and we are gradually establishing mechanisms and platforms that are conducive to the transformation of research results into clinical applications and the transformation of academic achievements into discipline brands, efficiency and core competitiveness, so as to create good environmental conditions for the application and transformation of scientific and technological achievements. (For more news, please pay attention to Yangcheng Pie pai.ycwb.com)
Source | Yangcheng Evening News Yangcheng Pie
Editor-in-charge | Lin Qingqing