wary! Choriocarcinoma loves to "target" women of childbearing age and should do a good job of tertiary prevention

After giving birth to three children, Ms. Li has been more than 2 months after childbirth, but the lochia has not been cleaned, she has always thought that her postpartum recovery is not good, and she has not paid attention to it. Until there was irregular vaginal bleeding, she went to the hospital for examination, but was startled by the diagnosis, the doctor diagnosed chorionic cancer.

Chorionic cancer is more common in women of childbearing age

Choriocarcinoma is a highly malignant tumor that generally occurs after mole, miscarriage, or normal childbirth, with a small proportion of patients following ectopic pregnancy, and mostly women of childbearing age.

Zhang Xihong, director of the Department of Gynecology of Zhengzhou People's Hospital, said that most of the disease is related to pregnancy, and the main symptoms in the early stage are miscarriage and abdominal pain.

Zhang Xihong said that the accompanying symptoms of chorionic carcinoma are mainly caused by distant metastasis of the tumor, mainly through hematogenous metastasis, which occurs early and extensively.

Lung metastases: most common, typically presenting with chest pain, cough, hemoptysis, and dyspnea, often acute onset, or a chronic persistent state.

Vaginal metastases: metastases are often located in the anterior wall and vault of the vagina, and once broken, they can cause irregular vaginal bleeding or even heavy bleeding.

Hepatic metastases: may manifest as pain in the epigastric or hepatic region, jaundice, etc., and if the lesion penetrates the hepatic envelope, intra-abdominal hemorrhage may occur.

Brain metastases: at first it can manifest as sudden falls, temporary aphasia, blindness, etc., followed by headache, hemiplegia, squirting vomiting, convulsions and even coma, and finally can form a brain hernia, compressing the life center, resulting in death.

For choriocarcinoma, it is necessary to do a good job of tertiary prevention

In the event of miscarriage, hydatidiform clearance, ectopic pregnancy, etc., it is necessary to follow the doctor's instructions for regular follow-up consultation, and cooperate with the doctor to perform color ultrasound and blood hCG examination.

Zhang Xihong said that chorionic carcinoma is currently the only malignant tumor with hope of cure. The treatment of choriocarcinoma is mainly chemotherapy, supplemented by surgery, through surgical treatment can control complications such as heavy bleeding, eliminate drug-resistant lesions, reduce the load caused by cancer cells, and shorten the course of chemotherapy.

For choriocarcinoma, three levels of prevention should be done:

Primary prevention: Women of childbearing age who do not have fertility requirements should do a good job of contraception.

Secondary prophylaxis: pregnancy history, regardless of miscarriage, term delivery, hydatidiform cessation, and ectopic pregnancy should be closely followed up, especially in women of childbearing age with high-risk factors.

Tertiary prevention: if there is abnormal bleeding and other symptoms, it should be treated in time, the diagnosis should be clear, and the treatment should be active.

If there is irregular vaginal bleeding, go to the hospital in time

Zhang Xihong said that nutritional status and socio-economic factors are possible high-risk factors for choriocarcinoma.

Dietary deficiency of vitamin A and its precursor carotene and animal fats has an increased probability of molars, and a significantly higher risk of chorionic carcinoma in those with a previous history of viticular mole disease.

Age is another risk factor for chorionic cancer, which has an increased incidence in women younger than 20 years and older than 35 years. In addition, miscarriage and infertility may also be risk factors.

If there is irregular vaginal bleeding, go to the hospital in time to exclude chorionic carcinoma. Usually pay attention to menstrual health and avoid unnecessary miscarriage, which is of great significance for preventing the occurrence of chorionic carcinoma.

(Zhengzhou People's Hospital Yu Hua)