Liu B, Kou Z, Chen B. Effects and mechanisms of traditional Chinese medicines on functional dyspepsia: A review [J]. Chin Herb Med, 2023, 15(4): 516-525.
中藥治療功能性消化不良的作用及機制綜述
功能性消化不良(FD)是臨床常見病和多發病。受環境因素、社會因素和飲食因素的影響，FD在普通人群中的發病率呈逐年上升趨勢。中藥在治療FD方面有着悠久的曆史和深遠的影響。以多成分、多目标、多管道的形式防治FD，效果明顯，優勢突出。本文從FD的常見證型入手，探讨單味中藥、有效成分及中藥治療FD的作用機制的研究進展，以期為FD的中藥治療提供理論依據。
關鍵詞：作用機制；半夏瀉心湯；柴胡舒肝散；功能性消化不良；中藥；枳術丸
Effects and mechanisms of traditional Chinese medicines on functional dyspepsia: A review
Bo Liu a, Zixiang Kou b,*, Baogui Chen b,*
Abstract
Functional dyspepsia (FD) is a common and frequently occurring disease in clinic. With the influence of environmental factors, social factors and dietary factors, the incidence rate of FD in the general population is yearly increasing. Traditional Chinese medicine has a long history and far-reaching influence in the treatment of FD. It can prevent and treat FD in the form of multiple-components, targets and channels, with obvious effect and prominent advantages. This article starts with the common syndrome types of FD, and discusses the research progress of single Chinese medicine, effective ingredients and the mechanism of traditional Chinese medicines in treating FD, in order to provide a theoretical basis for the treatment of FD with traditional Chinese medicines.
Keywords: action mechanisms; Banxia Xiexin Decoction; Chaihu Shugan Powder; functional dyspepsia; traditional Chinese medicines; Zhizhu Pills
Fig. 3. Mechanism of Banxia Xiexin Decoction in treating FD through JAK1/STAT3/ERK signal pathway.
Fig. 4. “Brain-gut” axis mechanism of Lianpo Drink in treating FD.