On December 5, Li Chuyuan, chairman of Guangzhou Pharmaceutical Group, announced at the International Science and Technology Brainstorming Conference that the results of the study showed that drinking Wang Laoji regularly can extend the life expectancy by 10%. Since then, the reaction of netizens is shown in the following figure:
(Image from Weibo screenshot)
A stone stirred up a thousand layers of waves, and the long-silent Wang Laoji herbal tea took advantage of this "anti-heaven divine effect" to fire, once again sent itself to the cusp of the storm, and claimed to be highly recognized by Yin Ye, president of Shenzhen Huada Gene Co., Ltd.
However, the president, who was inexplicably on the hot search, responded on Weibo that it was only a polite nod, but it did not mean that he agreed with this conclusion.
People who watch the twists and turns of the plot are dazzled, and Chun Yujun, like everyone else, is confused about the authenticity of Wang Laoji herbal tea, which is "anti-heaven divine effect", what is the truth?
It is understood that the "863" plan with the title of "Wang Laoji Extended Life" has been clearly defined in the relevant "Plan" issued by the State Council as early as 2015, including the 863 plan, which will be integrated into the national key research and development plan in 2017, and the original name will no longer exist. By 2017, the funding channels for science and technology plans (special projects, funds, etc.) before the integration of the "973" and "863" plans will no longer be retained.
The experiment with Wang Laoji herbal tea as the research object has faced integration and reorganization, and its authenticity and reliability have to be thought-provoking.
(Image from 123rf gallery)
The conclusion reached in the original text is that the statistical survival time of the female rat experimental group giving Wang Laoji herbal tea 2.90g/kg bw was 708.2 days, while the statistical survival time of female rats in the control group was 675.1 days, which was 33.1 days higher, and the difference was obvious, which proved that long-term drinking of Wang Laoji herbal tea had the effect of prolonging animal life.
At this press conference, Wang Laoji only announced the final experimental conclusions, but did not disclose any details related to the experiment.
Strictly speaking, what we don't know is that while the researchers of the Guangzhou Pharmaceutical Group came to this conclusion, whether they set up other multi-group control trials to prove that it was not disease, genetics, environment, etc. that affected the lifespan of the mice in the experimental group, but that it must be the factor of herbal tea that prolonged the aging of the mice.
In addition to the "statistical survival time" indicator, other indicators obtained by the experiment, such as the mortality rate of mice, the incidence of diabetes, heart disease, and hypertension, cannot be determined.
Professor Zhu Yi of the College of Food Science and Nutritional Engineering of China Agricultural University once revealed to the media that the national 863 plan for Wang Laoji is a study of functional entity safety evaluation factors, and the original intention is not to test whether he can prolong his life.
Without providing any specific experimental details, how can the conclusion of this experiment thrown out by Guangzhou Pharmaceutical Group be convincing to everyone?
Most drug or biological experiments give priority to the selection of research subjects as mice, one is because mice are easy to raise, the breeding period is short, the feeding cost is low, and the individual differences are low, on the other hand, because the genetic sequence of the mice used in the experiment is similar to humans.
However, a high degree of similarity does not equal exactly the same. In terms of the number of chromosomes, the number of human chromosomes is 42, the mouse has only 40, each chromosome but 1 chromosome carries about 1000 to 2000 genes, and there are about 98732436 different permutations and combinations... Species, which also determines the huge difference between the two organisms.
In the drug research and development institutions of many pharmaceutical companies at home and abroad, a large number of effective drugs will be tested on mice every year, and side effects or no effect will occur in people. Of course, such drugs can not be qualified for marketing through drug approval, nor can they be put into clinical use, which is one of the main reasons why drug research and development cost money, effort and time.
The industry usually believes that only when the epidemiological investigation, clinical trials, animal and cell experiments are roughly unified, can it be determined that there is a certain relationship between a certain practice and health, but according to a netizen who knows that there is no difference in the experimental results...
(Image from Zhihu screenshot)
Prior to this, the World Health Organization (WHO) through a large number of actual surveys around the world, can only determine that human health and longevity are affected by a combination of factors such as personal lifestyle, environmental, social and genetic factors, rather than the results based on a single factor.
So far, no drug or food has been proven by clinical trials: taking xx drugs/foods can increase life expectancy by 10%.
You must have seen this advertisement: if you are afraid of fire, drink Wang Laoji! According to the provisions of the National Health Product Advertising Law, the health care function claimed in the health food advertisement should be within the scope of approval by the State Food and Drug Administration, but the "fire prevention" proposed by Wang Laoji in the advertisement did not appear in the filing.
Chun Yujun searched that its health care function has only one and only one: clear throat and throat, and does not mention the effects of detoxification and detoxification, delaying aging, and the effects of "going to fire", "preventing fire" and "prolonging life" are not within the scope of the 27 health food functions approved by the Food and Drug Administration. (Seriously, have you been "fooled" by this ad for years?) ）
(The picture is from the screenshot of the official website of the State Food and Drug Administration)
According to the official introduction of Wang Laoji, Wang Laoji herbal tea is composed of honeysuckle, chrysanthemum, fairy grass, frangipani, summer dry grass, cloth residue leaf and licorice 7 flavor herbs, of which the most representative nutrients are chlorogenic acid, isochlorogenic acid, glycyrrhizic acid three.
Among the many literatures searched by Chun Yujun on CNKI, the article "Liquid-Mass Linkage Usage Analysis of 3 Active Ingredients in Wang Laoji Herbal Tea" has analyzed the content of these three components in Wang Laoji herbal tea, and the results are shown in the following figure:
(The data comes from the article "Liquid Mass Linkage Usage Analysis of 3 Active Ingredients in Wang Laoji Herbal Tea")
In the three batches of Wang Laoji herbal tea, the average contents of chlorogenic acid, isochlorogenic acid c and glycyrrhizinic acid were 17.76mg/l, 12.17mg/l and 6.36mg/l, respectively.
Although these three ingredients have been shown to have significant antioxidant, hypoglycemic and blood pressure, antibacterial and anti-inflammatory, anti-tumor, and lipid-lowering effects, what you don't know is that these three nutrients contained in Wang Laoji herbal tea have long been commonplace in vegetables and fruits.
In a bottle of 310ml of Wang Laoji herbal tea, the average content of the three ingredients is about: 5.5mg/l, 3.77mg/l, and 1.97mg/l. These three nutrients are contained in the vegetables and fruits you eat every day, such as sweet potatoes, spinach, greens, cabbage, oil wheat vegetables, oranges, longan, dragon fruit and other foods. Although you don't drink Wang LaoJi herbal tea every day, we will consume a certain amount of vegetables and fruits every day.
In addition, the addition of summer dry grass to Wang Laoji herbal tea has also been controversial, although the Guangzhou Pharmaceutical Group has repeatedly claimed that it is legal to add, but summer dry grass is not in the list of 87 kinds of Chinese medicinal materials that are allowed to be consumed by the Ministry of Health, nor in the "list of items that can be used for health food" published by the Food and Drug Administration.
In fact, even if there is no toxicity, is it really good for the body to drink the sweet Anding Jinjin Wang Laoji Herbal Tea? According to the standards proposed by the World Health Organization, in daily life, it is recommended to reduce salt and less oil, control sugar and limit alcohol, and recommend that the daily intake of sugar does not exceed 50 grams, and it is best to control it below 25 grams.
A large number of studies at home and abroad have also proposed that excessive intake of added sugars (such as white sugar added in herbal tea) can increase the risk of caries and overweight, sugar will also increase the risk of chronic diseases such as heart disease and type II diabetes, and excessive intake of sugar added to food will also increase the mortality rate of adult cardiovascular system diseases.
Although you can't see the fat that can make you fat in the traditional sense in the nutrients, you can't ignore the series of damage that polysaccharides in herbal teas can bring.
Postscript: Suppose this conclusion is true: drinking a certain amount of Wang Laoji herbal tea can extend the life expectancy of humans by an average of 10%. So, how much should you drink? 3 bottles per day or 1 bottle for 3 days? If there is really a standard answer, please tell Chun Yujun a sound, after all, Xiaobian is still afraid of death, and he does not know what to drink to prolong his life...
bibliography:
TAN Jianbin,HUANG Junming,ZHAO Min,ZHANG Jing,HUANG Xiaodan,CHEN Bifeng,ZHU Huanrong,YANG Xingfen. Experimental study on genotoxicity and teratogenic effects of Wang Laoji herbal tea[j]. S China J Prev Med,2013,39(06):84-89.
ZHU Pingchuan,CEN Weijian,FAN Xiaosu. Analysis of Three Active Ingredients in Wang Laoji Herbal Tea by Liquid-Mass Linkage[j]. Journal of Hubei University (Natural Science Edition),2014,36(02):123-126+131.]
Some of the contents of this article are compiled from Caixin, Economic Observation Network and other media.
Author: Meow Immortal
Copyright notice: This article is the original manuscript of Dr. Chunyu, the copyright belongs to Dr. Chunyu, unauthorized reproduction is prohibited, please contact [email protected] for authorization and cooperation matters