In autumn and winter, grapefruit is a favorite fruit of many people
But a woman in Wujin, Changzhou, suddenly caused a hypotensive shock after eating a grapefruit
What's going on?
Ms. Wang is 60 years old this year, usually low blood pressure, need to take medication control.
Photo / Visual China In early October, when she was visiting a fruit shop, she found fresh grapefruit on the market and bought two with the idea of tasting them. When she went home to eat one, she suddenly appeared dizziness, fatigue and other symptoms, and was immediately sent to the hospital by her family, after examination, Ms. Wang's dilation pressure was once as low as 50, and it returned to normal after rescue.
Tang Lidan, a pharmacist at the Clinical Pharmacy Department of Changzhou Second Hospital, introduced that grapefruit, also called grapefruit, is the offspring of a hybrid of sweet orange and grapefruit, and the flesh is red.
"This grapefruit itself has no effect on blood pressure, but it may interact with some antihypertensive drugs, resulting in an increase in the concentration of the drug in the body, an increase in efficacy, and a decrease in blood pressure that is too low."
It is understood that grapefruit contains furan coumarin compounds, which will slow down the metabolism of some drugs and prolong the time of action. In short, eating grapefruit at the same time as taking antihypertensive drugs is equivalent to increasing the dose of the drug.
Doctors suggest that when taking medicine, it is best not to eat grapefruit, because many drugs will be affected by "furan coumarin". Doctors recommend that patients taking the drug should preferably consume grapefruit after 72 hours of taking the drug. note! These drugs can not be taken with grapefruit antihypertensive drugs (such as nifedipine) grapefruit in addition to containing furan coumarin, can inhibit the metabolism of antihypertensive drugs, increase their blood concentration, grapefruit also contain potassium, potassium is a natural antihypertensive drug. If you take antihypertensive drugs while eating grapefruit, it is like overdosing the drug, causing a sudden drop in blood pressure, light dizziness, nausea, palpitation, and heavy cases of occasional angina, myocardial infarction or stroke.
Anxiolytic or sedatives Some anxiolytic drugs such as diazepam and midazolam cannot be taken with grapefruit, because grapefruit will prolong the action time of such sedative hypnotics, causing dizziness and drowsiness.
Antiallergic drugs (such as cismin, terfenadine) such as cismin, terfenadine, etc. can not be taken with grapefruit, because the consumption of grapefruit after taking such drugs will aggravate the adverse reactions of antiallergic drugs to the heart, liver and gastrointestinal tract.
Anti-rejection drugs (eg, cyclosporine) such as cyclosporine can not be taken with grapefruit because blood concentrations increase, adverse reactions increase, and liver and kidney toxicity increase. If such drugs are eaten with grapefruit for a long time, there is a risk of tumor induction.
Statins (such as atorvastatin) If taken with grapefruit, statins will rapidly increase the concentration of statins in the blood in a short period of time, greatly increasing the accumulation of drugs and toxic side effects, the most obvious side effects of statins are caused by rhabdomyolysis.
Finally delivered
Common contraindications to taking drugs ↓↓↓
The contraindications between drugs and foods are much more than the above,
So we must carefully read the instructions before taking the drug,
Or consult a doctor or pharmacist to find out the requirements and contraindications of taking medication,
in order to improve the safety of medication,
Do not use drugs blindly.
Source: Jiangsu News, People's Daily, Guangdong Health