Animal laboratories in the provision of services for human medical research, its potential biohazard risks must also be paid attention to, the use of disinfection equipment to sterilize the space and equipment is one of the measures to reduce the biosecurity risks of animal laboratories. This article will focus on the current disinfection methods of animal laboratories and the application of disinfection equipment.
Disinfection of laboratory animal rooms
First, the conventional disinfection method
At present, commonly used disinfection methods are ultraviolet disinfection, ozone fumigation, disinfectant wipes, etc.
Ultraviolet disinfection
Ultraviolet sterilization uses the appropriate wavelength of ultraviolet light to destroy the molecular structure of DNA (deoxyribonucleic acid) or RNA (ribonucleic acid) in microbial cells, resulting in growth cell death and/or regenerative cell death, achieving the effect of sterilization and disinfection. The penetration of ultraviolet rays is weak, so it is only suitable for disinfection of air and surfaces.
Ozone fumigation
Ozone can oxidize and decompose the enzymes needed inside bacteria, causing bacteria to die, and ozone can directly act on bacteria and pathogens, destroying their organelles, DNA, and RNA.
Disinfectant wipe
Use disinfection solutions such as peracetic acid or sodium hypochlorite to spray the room, wipe and disinfect the walls of the room, wipe and disinfect the operation of personnel with high requirements, and are prone to dead ends that are difficult to disinfect.
Second, the new disinfection method of animal laboratory
The first is the disinfection method with hydrogen peroxide as the medium, such as the hydrogen peroxide dry mist disinfection machine.
1. Disinfection mechanism
Dry mist hydrogen peroxide sterilization technology uses dry fog hydrogen peroxide sterilization technology to convert hydrogen peroxide into particles that are invisible to the naked eye, and plays a sterilization role through hydrogen peroxide, which is more active than liquid and has the ability to inactivate spores. Hydrogen peroxide gas easily generates free OH-, high-swimming OH-attacks cellular tissue components, including lipids, proteins, and DNA, thereby inactivating bacteria.
2. Sterilization guarantee level
Hydrogen peroxide has a broad-spectrum disinfection and sterilization effect, which can kill various bacteria, viruses and spores and other microorganisms in the air and on the surface of objects in confined spaces, and the sterilization guarantee level can reach log6.
Because hydrogen peroxide sterilization has the advantages of non-toxic secondary residue, fast, easy to verify, reliable and safe, this method is now commonly used in sterile areas, sterile laboratories, clean workshop space disinfection, killing all microorganisms, especially stubborn microorganisms and spores, viruses and superbugs. Automatic sterilization, remote control, program setting, safe without any residue, portable, easy to operate.
3. Advantages and application status
In terms of laboratory space disinfection, traditional ultraviolet irradiation, disinfectant spraying, and wiping account for a large proportion, due to poor repeatability and traceability, there are potential risks to laboratory personnel and the environment. With the standardization of laboratory management becoming higher and higher, some advanced disinfection methods have gradually entered people's field of vision.
Hydrogen peroxide is gradually accepted by laboratories, pharmaceutical factories and hospitals as a new, green disinfection method, and it has been confirmed that it can achieve a good disinfection effect on the air and surfaces of objects in the space.
However, many laboratory users have some concerns in their minds, worried that the poor material compatibility of hydrogen peroxide will cause corrosion to the equipment. At present, the construction of laboratories and laboratory animal centers mostly uses color steel plates, and due to the uneven quality of color steel plates on the market, once damaged, it will cause serious consequences.
Birinkohan KV-3000 dry fog hydrogen peroxide machine, in terms of fog particles, even far exceeds similar products in the EU, and is truly invisible to the naked eye. The dry mist close to the gaseous state does Brownian movement in the air, has good diffusion, can diffuse to every corner of the IVC cage, including the sanitary dead end, and completely kills the microorganism, completely decomposes the functional DNA substances in the microbial cells, so that the microorganisms cannot develop drug resistance. The consumption of hydrogen peroxide per unit of the Birinkohan dry mist disinfection machine that is truly fog-free is greatly reduced, which not only saves the user several times the cost of use, but also greatly reduces the risk of corrosion.
4. Advantages of hydrogen peroxide disinfection method
Based on more than ten years of disinfection experience, relying on the world's leading dry mist hydrogen peroxide disinfection equipment, and comprehensive experience in many animal laboratories in China, Novus provides a complete set of disinfection solutions for animal rooms, with the following characteristics:
- Safe and harmless: equipped with the country's leading disinfectant - Norfos space spleride, harmless to animals, friendly to personnel, non-toxic and non-corrosive, the sterilization process does not need to remove animals.
- Efficient sterilization: It can kill more than 200 harmful microorganisms, including H1N1, Ebola virus, meltoba spores and thermophilic spores, and can cope with the potential risks of animal experiments.
-The sterilization process is short: the entire sterilization + standing process does not exceed 1 hour, which significantly improves work efficiency and saves working costs.
- Small unit dosage: Very small amount of disinfectant per unit, which can be extremely low cost and avoid material corrosion, and better compatibility
-With provincial disease control test report and many qualification documents.
With the expansion of the scale of hospital animal laboratory construction and the global emphasis on biosecurity, the safety of animal laboratories will become more and more important, we should adopt more advanced disinfection technology and equipment to ensure the safety of animal laboratories, escort medical research and innovation.
Novus focuses on animal room disinfection, providing a full range of animal room disinfection methods and programs from space disinfection to sterilization and disinfection inside the IVC cabin.
Technical information, related consultation, please contact Zhang Gong
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Tel:0755-27417090