<h1> The original meaning of the "main limbs of the spleen" and the mechanism of the epiphyte field (original Li Maochun).</h1>
First, the original meaning of the mechanism of "spleen and stomach epidermis"
The two kinds of body cavity splitting methods of triodermal animals are formed from the inside of the primary intestine to the outside to form the body cavity structure, and the body cavity structure provides a spatial structure before the internal organs can be derived and developed, whether it is the fissured body cavity method or the tissue and organ development process formed by the intestinal cavity method, it is evolved from the order of the primary intestinal cavity - body cavity - appendage joint cavity.
Starting from the lateral mesenchymal development of the primary intestine: when the mesenchymal layer appears on the periphery of the primary intestine, the mesoderm develops the body cavity structure by the split-body cavity method and the intestinal cavity cavity, that is, the differentiation of the mesenchymal mesoderm develops around the body cavity structure, the intraluminal membrane serous layer is developed by the extension and differentiation of the endoderm, and the outer muscle layer of the serous layer is differentiated from the mesoderm.
When the body cavity structure is formed, the differentiation of the endoderm and mesoderm into the body cavity induces the migration of ectoderm cells to the body cavity, and the sympathetic nerve develops after coupling with the mesoderm differentiation branch, and the parasympathetic nerve is developed after coupling with the endoderm differentiation branch, and the three germ layer differentiation branches are gathered and coupled in the body cavity to form the "visceral embryo field" in the body cavity, and the embryonic field triggered by the split body cavity method and the intestinal cavity method is very different, resulting in the emergence of two kinds of humoral division animal phenomena.
Regardless of the split body cavity method or the intestinal body cavity method, when the "visceral embryo field" in the body cavity develops to a certain degree of saturation, the muscle layer of the outer wall of the body cavity will extend outward differentiation and development, inducing the ectoderm cells to move inward to the part of the outward extension and coupling with it, so a new embryonic field, that is, the emergence of the "appendage field", once this model is predetermined by the embryo, there will be a new evolutionary pattern, which is why no matter what kind of body cavity division of the animal, there is a mechanism principle for the evolution from no appendage structure to the attachment structure.
It should be noted here that the animal epiglot is genetically determined, so there is a diversity of animal appendages, and higher vertebrates have the phenomenon of appendage degeneration, such as the developmental movement of the snake degenerating the appendage, in other words, the appendage field does not necessarily have the paraphyte meridian mechanism.
Schematic diagram of the degeneration of the appendages of snakes
From the perspective of the two humoral division methods, whether it is the emergence of schizophrene exoskeletons and skeletal structures in the intestinal lumen, the development of the "visceral embryonic field" in the body cavity and the development of the "appendage field" outside the body cavity are all caused by the differentiation and development of the mesenchymal layer of the outer wall of the protointestinal tract to induce the internal migration coupling of ectoderm cells, and the mesoderm is the original group of the spleen tissue, so the organs and appendage structures in the body cavity are based on the spleen primordial basis in the development mechanism.
Schematic diagram of mesenchymal stem cell differentiation
This principle mechanism in ancient Chinese medicine is the principle of "spleen and stomach table theory".
The principle mechanism of the Principle is briefly described in the "Su Qing Tai Yin Yang Ming Theory":
The Yellow Emperor asked: Taiyin Yang Ming is in the surface, the spleen and stomach pulse are also, and what is the difference between those who are sick and different?
Qi Bo said: Yin and yang are heterogeneous, more virtual and more real, more inverse and more subordinate, or from the inside, or from the outside, from the different, so the disease is also a different name.
Emperor Yue: I would like to smell its strange form also.
Qi Bo Yue: Yang, the weather also, the Lord outside; the yin, the earth qi also, the Lord inside. Therefore, the yang is real, and the vagina is weak. Therefore, those who commit thieves and evil spirits receive it in the yang; those who do not eat and drink, and who live from time to time, suffer from the yin. If the yang receives it, it will enter the six houses, and if it is yin, it will enter the five Tibetans. When entering the Six Houses, the body is hot and lying down from time to time, and the upper is wheezing; when entering the Five Tibetans, it is (Yuezhen) full of occlusion, and the lower part is a catharsis, and it is long for the intestines. Therefore, the throat is the main weather, and the throat is the main earth. Therefore, the yang is subject to the wind, and the yin is subject to moisture. Therefore, yin qi travels from the foot up to the head, and downwards from the arm to the finger, and the yang qi goes from the hand to the head, and down to the foot. Therefore, it is said that the yang patient goes up to the pole and the yin patient goes down to the pole. Therefore, those who are wounded by the wind will receive it first, and those who are wounded by wetness will receive it first.
"Lingshu Jade Edition": The Yellow Emperor: May the pawn hear it. Qi: The one who receives the breath of man, the valley also, the one who injects the valley, the stomach also. Stomach people, Mizutani Qi and Blood Sea also. Where the sea walks, the world also. Those who produce qi and blood from the stomach are also tunneled. Those who pass through tunnels, the great network of the five internal organs, are only enough to take it.
The principles of the above two passages are all about the mechanism of the "visceral embryo field" in modern animal development and genesis, and the meaning of the text cannot be interpreted from the physiological level.
Second, the original meaning of the mechanism of "spleen master limb theory"
After the formation of the body cavity of the three germ layer animals, the first development of the body cavity "visceral embryo field", when the development is close to maturity, activate the "predetermined appendage field" formed during development, begin the differentiation and development of the appendages, from the formation of the primary intestine to the development of the "visceral embryo field", and then to the process of "epiphyte field" development, from the timeline of animal development and evolution is a long process, during which countless species of different levels appear; higher animal embryonic development repeats the development mode of lower animal embryos, No matter how advanced the animal development model, there are also low-level animal embryonic development mechanisms in it, and human embryonic development is naturally no exception. Modern medicine is still unable to establish a physiological diagnosis and treatment system from the developmental mechanism, but this principle mechanism has been used in ancient Chinese medicine for thousands of years, but Chinese medicine itself does not know.
Schematic diagram of the occurrence of the appendage field
SuQin Tai Yin Yang Ming Theory:
Emperor: Spleen disease and four branches do not need to be used?
Qi Bo Yue: All four branches are in the stomach, and they must not go to the scriptures, but they must be due to the spleen, but they are also blessed. Now the spleen disease can not be the stomach to do its liquid, the four branches must not be water valley qi, the qi is weakening day by day, the pulse is unfavorable, the muscles and muscles, all have no qi to live, so there is no need to cook.
This passage is talking about how the organs in the primary intestine and the body cavity form the mechanism of "internal organ embryo field", and has clearly told us that the unified mechanism of "internal organ embryo field" and "appendage field" occurs, because of the limitations of the times, successive generations of doctors can only use and play the principle of diagnosis and treatment, and cannot see the developmental pathogenesis mechanism behind the principle.
Emperor: The spleen and stomach are connected to the ears by membranes, and what can be done for them?
Qi Bo Yue: The foot taiyin is also the three yins, and its pulse runs through the stomach of the spleen, so the taiyin is qi in the three yins. Yang Ming's table also, the sea of the five Tibetan and six provinces, is also for the qi of the three yangs. The Tibetan governments are each affected by Yang Ming because of their sutras, so they are the stomach to carry their own liquid, the four branches are not allowed to be water valley qi, the day is getting worse and weaker, the vagina is unfavorable, and the muscles and muscles are not breathless, so there is no need to cook.
This passage is about the co-constructive development mechanisms of the "visceral embryonic field" and the "appendage field":
The process of protointestinal embryo formation is to repeat the development pattern of the two germ layer animals, the meridians formed by the functional segment of the protointestinal tract and the dorsal side of the embryo are co-constructed, and the meridians formed on the structure of the appendages are also co-constructed, that is, the yang meridians of the hands and feet, that is, the yang and the yang, that is, the yang and the yang, the sea of the five Tibetan and six provinces, also for which the qi is in the three yangs".
The development process of organs in the body cavity is to repeat the development mode of the triodermal animals, the differentiation of organs in the body cavity develops in the meridian co-structure formed on the ventral side of the embryo, and the meridians formed on the abdominal appendage structure are also co-constructed, that is, the hand and foot yin meridian, that is, "the foot taiyin is three yin, and its pulse runs through the stomach of the spleen, so the taiyin is qi in the three yin".
Human embryonic development repeats the development pattern of two germ layer animals and three germ layer animals to form a co-constitutive mechanism, this embryonic development model has always been a problem in modern animal development and genesis research, but it has been solved in traditional Chinese medicine, although it seems a bit too extensive, but this co-constructing mechanism of the two "embryo fields" is far beyond our imagination, this co-configuration mechanism is that "the Tibetan government is affected by Yang Ming because of its menstruation, so it is the stomach to do its liquid, the four branches can not be water valley gas, the day is getting worse, the vagina is unfavorable, Muscles and muscles have no breath to live, so they don't have to be fried."
The intestinal and appendages formed by the intestine and the appendages are co-existential through embryonic development, and the development of internal organs is co-constructed with the embryonic development of the appendages, and the mechanism of this co-configuration development is starting from the mesoderm, that is, the spleen primordial base, so Chinese medicine has come to the conclusion of "spleen main limbs", so we also really understand the real mechanism behind the "spleen main limbs" that we use for thousands of years.
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