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Elaborate on the composition of the ancient "Monghan medicine"

Menghan medicine, refers to the drug that makes people temporarily lose consciousness after taking it, which is actually the ancient name of anesthetic and has a general anesthetic effect. The history of Menghan medicine can be traced back to the Spring and Autumn Warring States Period, and it is said that the famous doctor Bian Que first used Menghan medicine for clinical use.

The Liezi: Tang Qing chapter records: "Lu Gonghu and Zhao Qi were sick, and they asked Bian Que to heal them." Bian Que then drank the poisonous wine of the two people, died for three days, dissected the stomach and probed the heart, easily ignored it, and threw a miracle drug. Having realized as before, the two resigned. It can be said that this poisonous wine is an anesthetic liquor containing sweat medicine, the so-called "ecstasy" refers to the temporary unconsciousness of people after the anesthetic acts, and the "miracle drug" is a wake-up agent with detoxification and detoxification functions.

The Book of the Later Han Dynasty, the Biography of Hua Tuo introduces the famous physician Hua Tuo of the Three Kingdoms period at the end of the Eastern Han Dynasty who inherited and summed up the experience of his predecessors, invented the earliest anesthetic in human history, Ma Boiling Powder, and used it to perform surgery for patients: "If the disease is issued internally, and the needle medicine cannot reach it, it is ordered to take Hemp Boiling Powder with wine first, drunk and unconscious, due to symptoms, caesarean section, extraction and accumulation... With the anointing of God, the symptoms will be cured in four or five days, and they will be calmed down in January. This means that for those patients who have diseases in the body, are ineffective with acupuncture and drugs, and must be treated surgically, Hua Tuo first let him take "hemp boiling scatter", and then "cut the abdomen and back to clear the disease" after he loses consciousness. It can be seen that the anesthesia effect of hemp boiling dispersion has reached a certain level.

When the Ming Dynasty physician Li Shizhen was young, he wrote in his "Linhu Pulse Science" that Menghan medicine was related to aconitum, and in middle age, he believed that the Chinese medicine "Oshi bulu" also had a paralyzing effect, and he recorded in the "Compendium of Materia Medica" that after taking it by mistake, "I don't know about adding a knife and axe", "A little grinding wine is drunk, then the whole body is paralyzed". In his later years, he also found that the "sheep flowers" smelled bitter, warm, and poisonous, and "thieves came to do it without doing it, so that they could eat it, so that people were drunk, and they tended to the basket, and after taking it, they fell asleep." ”

In modern times, the domestic Chinese medicine community has carried out exploration and research on Menghan medicine and Hemp Boiling Powder, and unveiled its mysterious veil: Menghan Medicine is mainly composed of mandala flowers, Chuan Wu and Cao Wu; while Ma Boiling Powder is mainly composed of Mantuo luo flowers, jasmine roots, calamus, Sichuan Dome and so on. Both parties use herbs with anesthesia to relieve pain, of which mandala flowers are the main ingredient.

Elaborate on the composition of the ancient "Monghan medicine"

Mandala flowers

Mandra flower: also known as the golden flower, mountain ash flower, drunken peach blossom, etc., is an annual herb of the solanaceae family, its roots, leaves, flowers, seeds are available for medicinal use, with asthma, cough, analgesia, anesthesia effect, which contains scopolamine and other ingredients.

"Compendium of Materia Medica": "According to legend, this flower laughs and drinks wine, which makes people laugh; dances to make people drink wine, make people dance." If you try it, you must drink it half-drunk, and make one laugh or dance to attract it. "Pick this flower in August, shade dry, hot wine to serve three dollars, less is drowsy, cutting fever, it is advisable to take this first, then do not feel pain also." "Raw Herbs Sexual Preparation": "Foreign golden flowers, food can kill people, confuse people." ”

After mandala flower poisoning, mainly for the central nervous system to show first excitement and then inhibition, small doses can make people feel tired, dizzy, sleepy, and then into dreamless sleep, the general dose can make people have a sedative effect, produce "forgetfulness", and then enter the anesthesia state, if combined with sleeping pills can produce a strong synergistic effect.

Mantuos flower not only has anesthetic effect, but also has a hallucinogenic effect, oral transducery system can be rapidly absorbed, distributed throughout the body, and block parasympathetic function, inhibition of the secretion of various glands, resulting in the appearance of dry mouth, hoarseness, dry skin flushing, dizziness and headache, decreased vision, slow or disappearance of light response, behavioral disorders, confusion, difficulty breathing, etc. In severe cases, the central nervous system is suppressed, resulting in coma, nausea, vomiting, etc.

Rescue method: use 100 grams of licorice, decoction, after the symptoms are alleviated, repeat the administration 1-2 times, or use mung beans, licorice and other parts, soaked in boiled water to take. If agitation and mania occur, sedatives such as tranquilizers such as tranquilizers and chloral hydration can be used, and if you have been unconscious or in shock, you can inject oxygen and if necessary, artificial respiration.

Elaborate on the composition of the ancient "Monghan medicine"

Silly sheep flowers

Sheep Flower: It is a flower of the wild deciduous shrub of the Rhododendron family, which has the effect of anesthesia, pain relief, blood invigorating and rheumatism. Folk commonly used sheep flower fresh products to engage in rotten external compresses, the treatment of neurological headaches, migraines, bruises, whether it is alcohol, powder, have analgesic effect, its roots and fruits also have similar to the flower anesthesia analgesic effect. In the Ming Dynasty's "Medicine Book", the bone-piercing Dan is matched with the fruit of the sheep flower with frankincense, musk and other compatibility to treat bruises, bruises, hematomas and pains.

Qing Dynasty "Medical Sect Jinjian" recorded osteopathic anesthetics is based on the sheep flower, with mandala, ephedra, Chuan Wu, grass Wu, etc., Sichuan Wu wu has anesthetic effect, and the compatibility with the haunting sheep flower can improve the anesthesia effect, but the Sichuan Wu cao Wu and the Yang Hua have the side effect of slowing down the heart rhythm, mandala has an anesthetic effect, and has the effect of speeding up the heart rhythm, so the compatibility with the Yang Flower can not only enhance the anesthesia effect, but also can antagonize the Yang Flower and so on to cause bradycardia, ephedra can also rise blood pressure, eliminate the blood pressure caused by the Yang Flower.

The juice of the sheep flower plus wine can make people lose consciousness and cause anesthesia, and is often used for surgical anesthesia. In ancient times, there was a "cup of drunken, a cup poured" of sacred wine, in fact, it may be added to the wine to make the juice of the sheep flower.

A small amount of sheep flowers can be analgesic and sedative, and large doses have anesthetic effect, which is first excited and then inhibited by the central nervous system, and taking more can be fatal. The amount of poisoning is generally 10-20 grams, some people take a flower can also lead to poisoning, mild poisoning is manifested as nausea, diarrhea, chest tightness and discomfort, rapid heartbeat first and then slow, drunken gait waddle, motor disorders, severe coma shock, unconscious.

Rescue method: you can use mung bean soup to detoxify, or induce vomiting, gastric lavage, in severe cases can be intravenous infusion of glucose saline and adrenal hormones, if necessary, oxygen transfusion, artificial respiration.

Elaborate on the composition of the ancient "Monghan medicine"

aconite

Aconitum: It is the root of the herbaceous genus Aconitum in the family Ranunculaceae, mainly the roots of Sichuan wu and grass wu. The main root is called aconitum because it is shaped like a crow's head, and Chinese medicine believes that aconitum is a big xin, big heat, big poison, and has the effect of dispelling wind and dehumidification, warm menstruation and relieving pain.

The poison of grass wu is more severe than that of Chuan Wu, and the ancients used grass wu as arrow poison: "The bird touches the fall, the beast encounters the stiffness, and the middle man also dies." "Compendium of Materia Medica": "Grass aconitum and ejaculation are poison medicines." The grass aconitum is taken out and dried as poison to shoot animals and beasts, so it is called shooting recklessness. Tao Hongjing said: "The hunter shoots and shoots the beast ten steps to fall, and the middle man also dies, so it is advisable to understand it, and it can be unloaded with licorice, mung bean, and small clover." ”

The main component of aconitum is aconitine, which has a strong anesthetic and analgesic effect, has an anesthetic effect on the central nervous system, can inhibit the respiratory center, and slows down breathing; the sensory nerve terminals of the skin are slightly excited and then paralyzed; palpitations, chest tightness, blood pressure decline, arrhythmia, etc. can appear in the cardiovascular system; there is an excitatory effect on the gastrointestinal vagus nerve, which can cause difficulty swallowing, nausea and abdominal pain; the respiratory system can lead to difficulty breathing, followed by paralysis shock.

Aconitine alkaloids are slightly soluble in water, can be absorbed through the digestive tract or from the broken skin, its absorption and excretion are very rapid, because the absorption is fast, so it can quickly cause poisoning, mainly through saliva and urine discharge, the human body has tolerance to aconitine, long-term use of small doses can make the body resistant to increase toxicity.

Rescue method: once poisoned, should immediately stimulate the throat area to cause emetic effect, and then use 1:5000 potassium permanganate liquid, 2% salt liquid or strong tea repeated gas lavage, after gas lavage, you can inject medicinal charcoal in the stomach, can play a role in adsorbing poison, and then inject 50% of glucose intravenously, accelerate the excretion of poison, if the poisoning time is longer, you can also take oral magnesium sulfate to induce diarrhea, reduce the absorption of the intestine.

Elaborate on the composition of the ancient "Monghan medicine"

An artemisia on the snow

Artemisia annua on the snow: a tuber of the Woolly Family of plants such as wrinkled leaf aconitum, short-stemmed aconitum, iron rod, etc. Mostly grown in alpine hillside grass or forest edge, the whole plant is highly toxic, with wind and dehumidification, blood and analgesia effect, the common amount is about 50 mg.

Folk are often used for rheumatic bone pain, neuralgia, bruises, poisonous insects and snake wounds. The analgesic effect of the total alkaloids contained therein is dozens of times that of morphine, and the combination with the golden flower can enhance the analgesic effect. The aconitum alkali it contains can stimulate the skin, make the skin mucous membrane produce a burning sensation, and then anesthetize the unconscious, and its local anesthetic effect is more than ten times higher than that of cocaine and procaine.

Snow on a branch of artemisia poisoning is generally about 3 grams, incubation period of about 10-30 minutes, overdose can lead to death, due to severe toxicity, poisoning can cause lips, tongue limbs, limbs limited activity, slurred speech, blurred vision, dizziness, irritability, convulsions and unconsciousness, etc., the digestive system can cause oral burning, nausea, vomiting, pontoons, abdominal pain, etc., the heart and blood system can lead to a variety of arrhythmias, and damage to the myocardium, the toxic effect on the heart is similar to digitalis poisoning.

Rescue method: once poisoned, the early stage should be immediately induced, and then with 1:5000 potassium permanganate liquid, 2% salt liquid or strong tea repeated gastric lavage, while oral magnesium sulfate solution to induce diarrhea. Ancient medical records record that when the poisoning of an artemisia on the snow is mild, it can be used to take raw licorice, mung beans, and decoction water nine times in a row, that is, solution.

Elaborate on the composition of the ancient "Monghan medicine"

Grandmaster Hemp

Zushi Hemp: also known as the Great Rescue Driver, Golden Belt, is a plant of the Ruixiang family Huang Ruixiang, Shaanxi Ganruixiang or Concave Leaf Ruixiang, which has the effect of anesthesia and pain relief, dispelling wind and communication, dispersing stasis and activating blood, and its sexual taste is hard, bitter and warm.

Legend has it that when thieves in ancient rivers and lakes were caught, they would inevitably suffer from flesh and skin, and even kill themselves. Therefore, I found a kind of "no pain" medicine, this kind of medicine powder is hidden in the neckline or inside the mouth and teeth, once caught and beaten, I will bite the medicine, general anesthesia, and naturally do not know the pain. This kind of medicine, which can make people not afraid to fight, was passed down among thieves, and later transferred to the people, and was used by doctors to treat diseases and cure diseases. This medicine is the famous painkiller - Zushi Hemp (can numb people without feeling pain, created by Zushi).

Zushi hemp contains zushi anesthex, raw products have strong penetration of the skin mucosa, direct use can strongly stimulate skin foaming, can make the skin mucosa inflamed, scarring, but ginger, licorice can significantly reduce its irritation, and its analgesic, sedative effect remains unchanged. Taking a large amount of zushi hemp can inhibit the motor nerve and central nervous system.

Rescue method: Once poisoned, the stomach should be washed immediately, and then injected with 50% glucose intravenously to accelerate the excretion of poisons, while oral magnesium sulfate diarrhea, reduce the absorption of the intestine.

Elaborate on the composition of the ancient "Monghan medicine"

jasmine

Jasmine root: for the genus Rhinoceros frangipani upright or climbing shrub plant, distributed throughout China, generally medicinal its roots, bitter, warm, toxic, containing alkaloids and sterols and other components, with anesthesia, pain relief, blood activation and other effects, for ancient popular common anesthetics.

The Ming Dynasty's "Materia Medica" records: "Grinding one inch of clothing with wine, then coma is awake for one day, two inches for two days, and three inches for three days." Those who have lost their bone joints and dislocated bone have used this, and they do not know the pain. "That is to say, grinding jasmine root with wine, internal administration can inhibit the central nervous system, can make people sleepy."

The Qing Dynasty literary scholar Ji Xiaolan once recorded a story of using jasmine roots to make "lovers eventually become dependents": There are two families in a village in Fujian, one of which has children and the other has a daughter. The children of the two families grew up with each other's admiration, but the parents of both sides strongly opposed the marriage between the two, and the girl did not marry the neighbor, and the boy also swore that she would not marry, so they dated privately, grinding juice with wine with 6-inch long jasmine root, and acting according to the plan. After the girl drank the medicine and wine, she did not wake up, as if she died, the girl's parents saw their daughter looking for a short sight, and after crying bitterly, they buried her in a coffin. At night, the young man came to the cemetery, dug up the tomb to open the coffin, rescued the girl, and when the girl woke up, the two flew away from home.

Rescue method: It is recorded in the "Compendium of Materia Medica" that once jasmine root is mistakenly poisoned and comatose, it can be detoxified with compound licorice soup, mung bean soup and so on.

Elaborate on the composition of the ancient "Monghan medicine"

Toad crisp

Toad crisp: for the toad glands behind the ear secretion of the white slurry, after the collection and processing of dried blocks, there are divided into clumps, flakes of two kinds, its taste is bitter, spicy, warm, toxic, the main components are cardiac steroid compounds, digitalis toxic glycosides, salmonidines, etc., in addition to indole alkaloids. It has the effect of detoxifying and relieving pain, strengthening the heart and opening the door.

Toad crisp has a strong local anesthetic effect, and the local anesthetic effect is dozens of times stronger than cocaine and procaine. It can be used alone, or it can be used in combination with Ikukawa U, Raw Grass U, Tiannanxing, etc. Immersed in 95% alcohol, topical local anesthesia surgery.

After toad crisp poisoning, symptoms appear in half an hour, and there are also up to 2 hours to appear symptoms, starting with epigastric discomfort, followed by nausea and vomiting, numbness in the lips and limbs, dizziness and salivation, and palpitations, arrhythmia and other symptoms similar to digitalis poisoning, and severe symptoms will also show irritability, convulsions, coma and so on. If the toad crisp powder enters the eye, it will cause severe pain in the eyes, tearing, corneal ulcers and other similar chemical damage.

Rescue method: early induction of vomiting, or gastric lavage with 1:4000 potassium permanganate solution, or atropine sulfate can also be used to inhibit the atrioventricular block and arrhythmia caused by the excitement of the vagus nerve caused by poisoning. If the toad crisp slips into the eye by mistake, it should be rinsed with plenty of water or saline, and then washed or dripped with comfrey juice.