Careful patients open the drug instructions of Zhenju antihypertensive tablets, and will find that the drug approval number is "National Medicine Quasi-character Z2006...", of which the English capital letter "Z" represents the meaning of Traditional Chinese medicine, so Zhenju antihypertensive tablets belong to proprietary Chinese medicine.
In the eyes of our ordinary people, most of them think, "Hmm! Eat some Chinese medicine is good, Chinese medicine does not hurt the body...", these inappropriate views will gradually be reversed with the in-depth development of patient medication education.
Any drug will have two sides, therapeutic effects and side effects, including Western medicine and pure Chinese medicine. For Zhenju antihypertensive tablets are slightly special, although it belongs to proprietary Chinese medicine, it contains both Traditional Chinese medicine ingredients and Western medicine ingredients, the composition is as follows: 1 Piece of Zhenju Antihypertensive Tablets In addition to wild chrysanthemum flower paste powder, nacre powder, these Traditional Chinese medicine ingredients, it also contains Clonidine hydrochloride 0.03 mg, hydrochlorothiazide 5 mg, rutin 20 mg these Western medicine ingredients. Therefore, it can be said that this antihypertensive drug is "simple but not simple"!
<h1 class="pgc-h-arrow-right">成分之一：盐酸可乐定</h1>
Coladine α receptor agonist, which can excite the peripheral sympathetic presynapaptic membrane alpha2 receptor, enhance its negative feedback effect, reduce the release of norepinephrine from the peripheral nerves, reduce peripheral vascular and renovascular resistance, and reduce blood pressure, but in the clinic, this drug is not used as a first-line drug for the treatment of hypertension!
The drugs mentioned above will have side effects, clonidine side effects can be seen: dry mouth, lethargy, dizziness, headache, mental depression, nervousness, anxiety, insomnia, constipation and sedation, decreased sexual function and nocturia, nausea, vomiting, anorexia, angioedema and rubella, fatigue, alopecia, rash, itching, hives, weight gain, fatigue, fatigue, withdrawal syndrome, abnormal liver function.
Therefore, the above side effects still exist after the combination of clonidine with traditional Chinese medicine. If you take Chrysanthemum antihypertensive tablets for a long time, the culprit of the sudden discontinuation of the drug and the "withdrawal symptoms" is "clonidine", and the patient can manifest as mental tension, emotional agitation, headache, tremor, with a sharp increase in blood pressure and an increase in the concentration of catecholamines in the blood plasma. In particular, after the combination of β receptor blockers (metoprolol, bisoprolol, aberolol, etc.), the above truncation symptoms are more likely to appear.
<h1 class="pgc-h-arrow-right">成分之二：氢氯噻嗪</h1>
Hydrochlorothiazide is a moderate-potent diuretic that increases the na + K + exchange of the distal tubule and the collecting duct by inhibiting the reabsorption of sodium chloride by inhibiting the reabsorption of the anterior and proximal tubules of the distal tubules, and increased K+ secretion. In other words, hydrochlorothiazide will affect electrolyte disorders in the human body, low sodium, low chlorine, hypokalemia, patients can appear limb weakness, chest tightness, limb numbness and other symptoms.
In addition, hydrochlorothiazide can lead to elevated blood sugar and hyperuricemia. Therefore, patients with a history of diabetes and gout can eat Chrysanthemum antihypertensive tablets, which can lead to aggravation, recurrence, and even more serious adverse medical events of the above diseases!
Hydrochlorothiazide has cross-allergic reactions with sulfonamides, furosemide, bumetanide, carbon anhydrase inhibitors, etc. Therefore, those who have been allergic to the above drugs in the past, taking Zhenju antihypertensive tablets without their knowledge can lead to serious allergic reactions to drugs!
<h1 class= "pgc-h-arrow-right" > ingredient three: rutin</h1>
Rutin belongs to one of the vitamin P, vitamin P is a hydrogen transmitter, may participate in the role of oxidoreductase in the body, can affect the activity of the thyroid gland, and make adrenaline immune from oxidation, in the body, can enhance the role of vitamin C and promote the accumulation of vitamin C in the body, the body is deficient when the capillary fragility increases, its main pharmacological effect is to maintain vascular elasticity, enhance capillary resistance, reduce its fragility and permeability, and promote its cell proliferation and prevent blood cell agglutination. Also has anti-inflammatory and anti-allergic effects. However, the drug instructions also mention: "This product is almost not absorbed in the body, so its oral efficacy is not accurate", therefore, with wild chrysanthemum cream powder, nacre powder these traditional Chinese medicine ingredients and clonidine hydrochloride, hydrochlorothiazide after the drug efficacy is worth further discussion!
<h1 class="pgc-h-arrow-right">改变观念，重视合理用药</h1>
Most people think that the side effects of Traditional Chinese medicine and proprietary Chinese medicine are mild or even no side effects, but some drugs are "Z", but some drugs are "Z", but they may contain a variety of Western medicine ingredients, so they cannot ignore their side effects. At the same time, the state is also making great efforts to collect and improve the side effects of "pure Chinese medicine" preparations in your eyes according to the annual adverse drug reaction reports, and some drugs even add warnings, all of which are based on rational use of drugs as the starting point to improve the public's attention to drug side effects!
<h1 class="pgc-h-arrow-right">长期服用降压药，选择A、B、C、D更加适宜</h1>
A: ACEI "pralips" or ARB "sartans", representing drugs such as benazepril, enalapril, lisinopril, valsartan, losartan, irbesartan, telmisartan, olmesartan ester, candesartan ester, etc. Such drugs with blood creatinine > 265.2ummol/l, and blood potassium concentrations greater than 5.5mmol/l are contraindicated in patients! Alternatively, the appropriate medication may be selected based on the patient's specific complications, such as hypertension with high uric acid, and losartan may be more appropriate. Because losartan has the effect of lowering uric acid.
B: β receptor blocker "lore class", representing the drug metoprolol tartrate, metoprolol succinate, bisoprolol and so on. Such drugs should pay attention to bradycardia, hypotension, and central nervous system side effects. Among them, metoprolol tartrate is taken on an empty stomach, with the aim of maintaining a stable blood concentration and reducing the incidence of side effects. Some people say that extended-release tablets cannot be broken, but melolovolol succinate extended-release tablets can be broken open and eaten, but they cannot be crushed or crushed. In addition, metoprolol succinate extended-release tablets 47.5 mg are comparable to metoprolol succinate 50 mg.
C: CCB "horizon class", representing the drugs nifedipine, felodipine, amlodipine. Among them, nifedipine controlled release tablets, when some people do patient education, also point out not to break open and not to crush, this kind of instruction is right, but sometimes out of reality, nifedipine controlled release tablets (Bai Xintong) belong to the skeleton structure, it is difficult to crush, crush or break open, so patients also avoid this wrong medication method! In addition, during the medication process, ankle edema, hypotension and other side effects appear in time to see a doctor, do not ignore it!
D: diuretics, representative drugs are hydrochlorothiazide, furosemide, spironolactone and so on. Spironolactone is a bit special, it belongs to the potassium-sparing diuretic, hydrochlorothiazide, furosemide is easy to cause hypokalemia, and spironolactone is easy to cause hyperkalemia, therefore, during taking the drug to do a good job of medication monitoring, to prevent the side effects of the corresponding drugs!
<h1 class="pgc-h-arrow-right">4+7带量采购的落地，使咱们老百姓实实在在的用到有效且便宜药</h1>
4 + 7 with quantity procurement, so that the above a variety of Western drugs antihypertensive drug price reduction drug price reduction 80%. At the same time, through the development of drug consistency evaluation, under the premise of reducing drug prices, the efficacy of drugs has also been guaranteed, and we ordinary people please rest assured that we can use drugs! For example, the antihypertensive drug amlodipine besylate tablets (5mg) 21 tablets, 14 tablets, 7 tablets of the three specifications of the product to be selected, the quotation is 1.19 yuan / box, 0.84 yuan / box, 0.49 yuan / box, the price of a single tablet dropped to only a few cents, greatly reducing the economic burden of the people's medication! #2021 Spring Festival Medical Road Guardian ##Pharmaceutical Health Super Energy Group ##健康2021 #
加强公众对药品所含成分的用药教育，有助于患者减少重复用药，减少药品副作用发生率！ Change the original "Chinese medicine" has no side effects or small side effects, can be taken casually or discontinued at will! Rational drug use has always been on the road, doctors, pharmacists, patients work together to promote safe, effective, economical and appropriate medication!
<h1 class="pgc-h-arrow-right">关注我@毕先生，每天科普一点点，您的健康多一点！ Code words are not easy, if you find it helpful, please forward it to benefit more people! </h1>