The director of the Department of Gastroenterology said bluntly: Eating probiotics for ulcerative colitis is very effective!
Many patients with ulcerative colitis are particularly confused: they clearly follow the doctor's instructions, take medicine on time and in accordance with the amount, be cautious in their diet, and combine work and rest, but why do they still feel uncomfortable in the abdomen, sometimes with dull pain, sometimes with bloating, and sometimes with unformed stools. And as long as there is a slight negligence in eating, the condition will recur, and even get worse?
In fact, the reduction or disappearance of the previous symptoms is only the anti-inflammatory effect of the drug, and the root cause of ulcerative colitis has not been really removed. Once the drug is stopped, without the protection of beneficial bacteria and the bacterial film barrier, it will not be long before the harmful bacteria will make waves again. The intestinal mucosa is constantly stimulated by toxins and rubbed back and forth by feces, and the intestines become particularly sensitive, and recurrence of the disease is inevitable.
You must know that all enteritis problems start from intestinal flora imbalance, and only by restoring the intestinal microbiota to a healthy and balanced state can it really end! Therefore, probiotic supplementation is very important and necessary for the complete recovery of ulcerative colitis, which has also been affirmed and strongly recommended by many hospital experts!
For example, some patients feel that their symptoms have lessened and stop taking the drug on their own, only to have a worsening condition within a few days. There are also patients who do not pay attention to probiotic supplementation, and the intestines have always been in a fragile state, and the condition is always recurring. However, those patients who insisted on following the doctor's advice and supplemented probiotics with the help of drug treatment at the same time gradually returned to normal, the condition was well controlled, and the quality of life was greatly improved!
Professor Zhao Weigang from the Department of Gastroenterology of the First Affiliated Hospital of the University of Science and Technology of China pointed out that patients with ulcerative colitis are very beneficial to drink probiotics, which have the following benefits:
First, probiotics are made by bacteria, killing harmful bacteria, not harming beneficial bacteria, quickly inhibiting the living space of harmful bacteria in the colon, greatly reducing the number of harmful bacteria and the toxins secreted by them, improving the structure of intestinal flora from the root, helping to improve ulcerative colitis and prevent recurrence.
Second, probiotics will form a layer of probiotic protective film on the ulcer surface, which is called the bacterial membrane barrier (the bacterial membrane barrier plays a triple protective role in the intestinal mucosa such as chemical barrier, biological barrier, and immune barrier), which is equivalent to the role of a band-aid, with this protective film, the damage to the ulcer surface is much smaller, and the ulcer surface heals much faster.
Third, ulcerative colitis is an immune disease because the defenses of the colonic mucosal cells themselves decrease. Probiotics have the effect of activating the autoimmunity of colonic mucosal cells, and daily supplementation of probiotics is very helpful to prevent the recurrence of colitis.
Fourth, probiotics improve the structure of intestinal flora, reduce the stimulation of intestinal endotoxins and harmful bacteria to the intestinal mucosa, and form a bacterial membrane barrier on the surface of the intestinal mucosa, inhibit the formation of polyps and reduce the rate of cell malignancy.
However, not all probiotics are suitable for ulcerative colitis, and the selection of probiotics for ulcerative colitis should meet the following six conditions at the same time:
Condition 1: There is a Chinese invention patent certificate related to "improving ulcerative colitis".
The "invention name" of the Chinese invention patent certificate must be related to "improving ulcerative colitis", otherwise, no matter how many patent certificates there are, they are worthless.
For example, Lactobacillus reuteri JYLB-291 in the probiotic formula of Huojun No. 1 brand won the China invention patent No. ZL 2021 1 1566079.0 with the invention name of "improving ulcerative colitis", and Lactobacillus casei L. casei21 in the probiotic formula of Huojun No. 1 brand won the China invention patent No. ZL 2021 1 with the invention name of "therapeutic effect on diarrhea". 0242478.5;Bifidobacterium longum JBLC-141 in the probiotic formula of Huojun No. 1 brand won the China invention patent number ZL 2021 1 0227019.X for "scavenging free radicals in the human body".
The theory of free radicals believes that free radicals are the source of all diseases, and free radicals are the culprits of human aging and tumor formation! Free radicals attack normal immune cells, making them abnormal; Abnormal immune cells will attack normal immune cells, resulting in immune reactions, which in turn induce immune diseases, and autoimmune factors are important triggers of ulcerative colitis! Abnormal immune cells also attack the intestinal mucosal cells, leading to inflammation that can lead to ulcerative colitis. Therefore, Bifidobacterium longum JBLC-141 in the probiotic formula of Huojun No. 1 brand is very important and necessary for the comprehensive recovery of ulcerative colitis because it enhances the function of "eliminating excess free radicals in the body, preventing the loss of free radicals to body cells, and can also play a certain role in protecting cell oxidative damage and relieving body fatigue".
Condition 2: The probiotic is specially formulated for ulcerative colitis.
There are as many as 400 kinds of probiotics in the human body, and different strains form different formulas, and their functions and suitable groups will be different. In addition to the above three Chinese invention patent strains to improve ulcerative colitis, the other three probiotics and prebiotics are also very beneficial to ulcerative colitis.
For example, Lactobacillus acidophilus JYLA-191 and Bifidobacterium juvenile BBF-06 in the probiotic formula of Huojun No. 1 brand have been jointly experimented by many hospitals and medical universities (excerpted from the 7th issue of the Chinese Journal of Digestion in 2008), and the results show that the combination of Bifidobacterium juvenile and Lactobacillus acidophilus can effectively maintain the remission of experimental colitis, which is conducive to the restoration of normal weight and health, inhibition or killing pathogenic bacteria, and rebuilding the intestinal microecological environment is conducive to the continuous remission of ulcerative colitis. Lactobacillus acidophilus JYLA-191 obtained the Chinese invention patent number: ZL 2021 1 0237827.4
Another example: Lactobacillus paracasei JLPF-176 in the probiotic formula of Huojun No. 1 brand, Yang Ziyan of Guangdong Medical University in "Research on the immunomodulatory effect of Lactobacillus paracasei on DSS-induced colitis in mice" concluded that Lactobacillus paracasei has good gastrointestinal fluid tolerance and good safety, and can alleviate the symptoms of colitis in mice. People with ulcerative colitis often have a bad stomach and may even be co-infected with Helicobacter pylori, Lactobacillus paracasei JLPF-176 won the Chinese invention patent number of "inhibiting Helicobacter pylori infection": ZL 2021 1 0066239.9.
Finally, according to the journal paper "Research on the Effect of Fructooligosaccharides on the Intestinal Mucosal Barrier of Ulcerative Colitis Model Mice 0120170401670232 the Collection of the Institute of Scientific and Technical Information of China", the prebiotic "fructooligosaccharides" selected by Huojun No. 1 brand probiotics concludes that fructooligosaccharides can improve the intestinal microbiota barrier function of ulcerative colitis model mice, increase the levels of slgA and anti-inflammatory cytokines IL-10 in the intestinal mucosa and reduce the levels of inflammatory cytokines TNF-a and IL-6. By regulating the excessive immune response of the intestines, the immune barrier function can be restored to a certain extent.
Condition 3: The strain of this probiotic formula has been clinically controlled to improve ulcerative colitis, and it is truly effective.
Not all strains in the probiotic formula have been clinically controlled trials to improve ulcerative colitis. Most of the probiotics on the market are not drug standards, so we can't tell whether this probiotic has a real effect on ulcerative colitis.
For example, some probiotic products are advertised in a fanciful manner, but when asked whether there have been relevant clinical trials to prove that they are effective against ulcerative colitis, they are speechless. There are also many common probiotics, because they are not drug standards, there is no reliable basis for the effect of treating ulcerative colitis. Therefore, when we select probiotics for ulcerative colitis, we must carefully identify the strains in the formula, and have we done clinical controlled trials to improve ulcerative colitis? Is it real and effective?
For example, Lactobacillus reuteri JYLB-291 patent number ZL 2021 1 1566079.0 in the probiotic formula of Huojun No. 1 brand can verify that the patent details are true and effective: the combined drug can be used to cause pus and blood in the fecal mucosa, abdominal pain, increased stool frequency, loose stools, etc., with a total effective rate of up to 95.7%, and the results of the functional control test are:
For example, Lactobacillus casei L.Casei21 patent number ZL 2021 1 0242478.5 in the probiotic formula of Huojun No. 1 brand can verify that the patent details are true and effective: the combined drug can be used to treat abdominal pain, diarrhea, frequent bowel movements, and lukewarm limbs caused by enteritis, with a total effective rate of up to 92% in 30 days, and the results of the functional control test:
Condition 4: The individual live bacteria content of each strain of this probiotic to improve ulcerative colitis is high enough, not less than 5 billion!
Many probiotic products claim to have a high total amount of live bacteria, but those separate, higher-cost star strains have very low or even no labeling at all, which is simply shoddy. The strain number is like an ID card for probiotics, with it, the source can be traced, and safety is guaranteed. You must know that the cost of different strains varies greatly, and the effect of action is also very different. According to the latest regulations of the state on probiotic packaging labeling: in the ingredients of probiotics, the strain number of each probiotic must be clearly marked, as well as the individual content of each strain.
For example, some unscrupulous merchants label a high total content of live bacteria, but in fact, the content of key star strains is very small, and consumers are kept in the dark. For another example, because a probiotic product is not labeled with the strain number and individual content, consumers cannot judge its quality, and the effect is not good after use. However, those products that are labeled in strict accordance with the regulations allow consumers to choose clearly, and they are more assured to use and have better results.
For example, the probiotic packaging of Huojun No. 1 brand clearly identifies the strain number of each probiotic and its individual live bacterial content, and the Chinese invention patent strain JYLB-291 JYLB-291, which is added with "improving ulcerative colitis", is not less than 10 billion per bag; Each bag is supplemented with no less than 10 billion Chinese invention patent strain L.Casei 21 with "therapeutic effect on diarrhea", and no less than 5 billion Chinese invention patent strain JBLC-141 with "scavenging human free radicals" added to each bag; Each bag contains more than 10 billion Lactobacillus acidophilus JYLA-191 and more than 10 billion Bifidobacterium juvenile BBF-06.
Condition 5: The probiotic must be a probiotic of raw powder.
What is raw powder probiotics? It is in the ingredients of this probiotic, except for probiotics and prebiotics, there is nothing else, neither food excipients are added, nor food additives, and there are no substances that are easy to cause allergies. This is like Moutai puree, which has not been blended, and the cost is quite high!
For example, probiotics like the No. 1 brand of Huojun are raw powder probiotics, and its ingredients are nothing except six kinds of probiotics and a prebiotic (fructooligosaccharides), pure raw powder, and the true content of six live bacteria in each bag is not less than 50 billion.
Patients with ulcerative colitis are particularly sensitive to the intestines, and many food excipients or food additives may cause lactose intolerance or allergic reactions, which can make the symptoms of enteritis more severe. Therefore, patients with ulcerative colitis are suitable to supplement with raw powder probiotics.
For example, some patients do not know this, and they randomly supplement probiotics containing a variety of added ingredients, which leads to intestinal discomfort and aggravation of the disease. And those patients who choose raw powder probiotics can be better accepted by the intestines, and the symptoms can also be effectively improved. For another example, a patient has allergic symptoms due to the supplementation of inappropriate probiotics, and the enteritis is becoming more and more serious. However, after switching to raw powder probiotics, the situation gradually improved.
Condition 6: The strain of the probiotic must be alive to reach the intestinal tract, with a high survival rate, a high colonization rate, and a high reproduction rate.
Patients with ulcerative colitis have a severe imbalance in their intestinal flora, which is filled with a large number of harmful bacteria. You must know that only probiotics in the state of live bacteria have the ability to fight against harmful bacteria, and the number of live bacteria must be large enough, after all, there are many bacteria and great power. If the content is too low, not only will it not be able to destroy harmful bacteria, but it may also be defeated by harmful bacteria.
Probiotics, a low-end organism, are quite fragile in life. In the summer, the high temperature outside the body can kill them, and when exposed to the air, they will be dried up by oxygen, and even if they pass through the digestive tract to the intestines, they will be destroyed by saliva, stomach acid, bile and other digestive juices. Therefore, the strains of probiotics must be domesticated with acid, oxygen and high temperature resistance, and they must be treated with special technology, so that the viable bacteria rate, colonization rate and reproduction rate of this probiotic can be high after reaching the intestine.
Some probiotic products do not go through these strict treatments, and they are quickly eliminated after entering the human body, and they do not work at all. Probiotics that have been carefully domesticated and treated with special technology can successfully survive, colonize and multiply in the intestines, effectively improving the intestinal environment and helping patients fight diseases. For another example, some patients use probiotics of poor quality, which not only has no effect, but may also worsen the condition. But if you choose the right quality probiotics, you can see a significant improvement.
For example, Wuhan Huojun No. 1 Health Industry Co., Ltd.'s high-end customized Huojun No. 1 probiotics, its strains have been domesticated to a certain extent with acid, oxygen and room temperature resistance, and the patented strains of Huojun No. 1 Lactobacillus reuteri JYLB-291, Lactobacillus casei L.Casei21, Bifidobacterium longum JBLC-141, Lactobacillus paracasei JLPF-176, etc., have good acid and bile resistance special activities, and use JIAYIO?-BIO probiotics two multi-layer coating storage technology. It comprehensively solves the problem of probiotics afraid of acid and bile, and the rate of reaching intestinal viability is as high as 95%. At the same time, it adopts special solid-state dormancy technology and JIAYIO?-GUARD live bacteria freeze-drying protection technology, that is, it is fixed in a state after production, does not need cold chain storage and transportation, and can withstand high temperature storage and transportation in summer without losing activity.
Friendly reminder: There are thousands of probiotics, don't buy the wrong one! To buy authentic Huojun No. 1, look for the flagship store of Jingdong Huojun No. 1, or the official enterprise store of Taobao Huojun No. 1.
(Author's statement: academic discussion, for reference only)