Vitamin C is an acidic hexose derivative of fresh fruits, also known as "ascorbic acid". Years of basic animal experiments and clinical studies have found that vitamin C not only has a health care effect in helping growth and development, improving immunity, etc., but also plays an important role in skin beauty.
Vitamin C is a strong reducing agent, with antioxidant effect, due to its molecule has optical rotation activity, according to its optical rotation, it can be divided into left-handed and right-handed, of which L-vitamin C can lighten pigmented spots, help synthesize collagen, and delay skin aging.
Pigment adhesion
Tyrosinase is an important mediator in the process of melanin formation, a catalyst for tyrosine to convert to melanin, and a rate-limiting enzyme that regulates melanin production, so it is an important factor in the occurrence and development of melasma.
Role of L-vitamin C[1].
Xu Tianhua et al. [2] selected subjects with yellowish complexion and enlarged pores, and after the introduction of L-vitamin C into the cheeks, the melanin index (MI) value on the treatment side decreased, suggesting that L-vitamin C can effectively whiten the skin and improve skin brightness, and the effect has been seen after 1 week of use, and the whitening effect of the cheekbones is more obvious in the second week.
Photoaging
Skin photoaging refers to the chronic damage caused by long-term exposure to ultraviolet rays and aging of the skin, which is mainly manifested as decreased skin elasticity, wrinkles, and dull complexion.
L-vitamin C acts as an antioxidant and has been shown to have skin photoprotective effects that can be [3].
Li Kunjie et al. [4] grouped the photoaging rat models, and found that the dermal collagen content of the rats in the combined L-vitamin C treatment group increased significantly after intensive pulsed light and topical L-vitamin C treatment, which could accelerate the repair of the skin barrier.
Vitamin C can be used alone or in combination with lasers, oral drugs and other treatments, and its role in skin cosmetic is increasingly recognized by the industry.
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[1] Li J . Effect of vitamin C iontophoresis combined with photorejuvenation in the treatment of facial melasma [J]. Laboratory Medicine & Clinical Medicine,2019,16(15):2216-2218. DOI：10.3969/j.issn.1672-9455.2019.15.033
[2] Xu Tianhua, Li Yuanhong, Zhu Xia, et al. Clinical study on the efficacy and safety of L-vitamin C whitening and wrinkle removal[J].Chinese Journal of Aesthetic Medicine, 2009, 18(12):3.DOI:10.3969/j.issn.1008-6455.2009.12.037.
[3] Li Min, Zhen Yaxian. Protective effect of topical antioxidant preparations containing vitamin C, ferulic acid and phloretin-induced skin photodamage[J].Chinese Journal of Dermatology,2010,43(6):447-448.
[4] Li Kunjie, Xu Tianxing, Guo Yanni. Study on L-vitamin C combined with laser for photoaging skin treatment in SD rats [J]. Dermatology & STD, 2017,39(3):157-160.doi: 10. 3969 /j. issn. 1002 － 1310. 2017. 03. 001.