As the saying goes, "if you have a problem with your intestines, you only have half a life left", and once you suffer from ulcerative colitis, it is very easy to fall into a vicious circle of "effective when taking medication, recurrence after stopping medication, and long-term treatment cannot be cured, but becomes more and more serious". Patients have to endure various pains such as "abdominal pain, mucus and bloody stools, loose stools, and increased frequency of bowel movements" all year round, and at the same time, they have to worry about the possibility of cancer, and need to go to the hospital regularly for colonoscopy screening, which has a very serious impact on the quality of life of patients.
Some doctors even directly tell patients that the cause of ulcerative colitis is not clear, and it is extremely difficult to achieve a radical cure in clinical practice, and in order to prevent the disease from aggravating and becoming cancerous, it is generally necessary to rely on taking medicine for life to control it, which brings great mental pressure to patients. In today's era of highly advanced medical technology, cancer can be cured, but why is ulcerative colitis difficult to completely cure?
This is because the colon is a very special organ, it is the only way for feces to form and excrete, it can be said to be a place to hide dirt and dirt, which contains a large number of bacteria, viruses, parasites, pathogens, protozoa and other microorganisms. In the intestinal tract of healthy people, the beneficial bacteria occupy an absolute advantage, the harmful microorganisms are at a disadvantage and are suppressed, and the neutral bacteria are also in peace. Numerous beneficial flora will also form a protective film on the surface of the intestinal mucosa, which is called the "bacterial membrane barrier" in medicine, which can play a triple protective effect on the intestinal mucosa as a "chemical barrier, biological barrier, and immune barrier".
Once you suffer from enteritis, it means that the healthy balance of the microecology is broken, the harmful bacteria occupy the upper hand, the beneficial bacteria are in the downwind, the neutral bacteria also see the wind to make the rudder start to do evil, the bacterial membrane barrier disappears, the inflammatory surface of the colonic mucosa is directly exposed to the intestines, and every day it is subject to the erosion of harmful microorganisms, the stimulation of toxins and chemicals and the friction of feces, not only is it not easy to recover, but in the long run, erosion, perforation, proliferation, etc., and even cancer, This is the reason why the rate of ulcerative colitis over five years old increases year by year.
Because the cause of ulcerative colitis is not clear, traditional drug treatment is mainly anti-inflammatory to control inflammation and relieve painful symptoms such as fecal mucus and bloody stool, abdominal pain, diarrhea, tenesmus and other painful symptoms, but it does not fundamentally improve the structure of intestinal flora, restore microecological balance and bacterial membrane barrier. Once the drug is stopped, the protection of the beneficial bacteria and the bacterial membrane barrier is lost, and after a period of time, the harmful bacteria are very easy to come back and recur, just like the beginning, and you have to start taking the medicine again.
As the saying goes: "medicine is three parts poison", long-term medication is tantamount to chronic suicide, can we only wait for death?
Definitely! At the same time of drug treatment of ulceration, supplementation of probiotics may make up for the deficiency of single anti-inflammatory drugs and achieve the effect of clinical cure. Therefore, many doctors prescribe anti-inflammatory drugs such as mesalazine for ulcer patients, and also prescribe probiotics such as Bifidobacterium Triple Viable Powder, Clostridium butyricum Live Bacteria, Bacillus cereus, Clostridium butyricum Enterococci Triple Viable Tablets and other drug quasi-brand probiotics. However, most of these probiotics are products with approval numbers before 2006, with a single strain of formulation, a single strain function, and low activity and content of strains, which have limited effect on improving the structure of intestinal flora in ulcer patients, and it is difficult to achieve the goal of clinical cure.
Now, though, things are different! Continental has a patented strain formula that is specially designed to improve ulcerative colitis - "Huojun No. 1".
According to the patent details published by the Patent Office of the State Intellectual Property Office, the star patented strain of Lactobacillus reuteri JYLB-291 can effectively tolerate gastric acid and bile salts and colonize the intestine, thereby improving the intestinal microbiota and creating a favorable environment for the improvement of the disease. At the same time, this strain can also regulate the balance of pro-inflammatory factors and anti-inflammatory factors, thereby playing a role in improving ulcerative colitis, and won the Chinese invention patent No. ZL 2021 1 1566079.0.
Ulcerative Colitis Clinical Trial 1:
A total of 100 patients with ulcerative colitis whose primary symptoms were mucus and pus, abdominal pain, increased stools, or loose stools were included in the study, including 48 males and 52 females. The patients were divided into control and experimental groups with 50 cases in each group. There were 25 male and 25 female patients in the trial group, aged between 20 and 65 years, with a mean age of 45.8 years, a duration of 1 to 10 years, and a mean duration of 4.8 years; Forty-two patients had fecal mucus, pus and blood, 35 patients had abdominal pain, 50 patients had increased stool frequency, and 47 patients had loose stools.
Patients in the experimental group were treated with mesalazine (0.4g) with 2 tablets each time, 3 times a day; At the same time, Lactobacillus reuteri JYLB-291 was administered once daily at a dose of 1×108 cfu/kg body weight.
The duration of treatment lasts for 30 days. The results showed that patients with ulcerative colitis were significantly more effective in the treatment of the four most typical symptoms (stool mucus and blood, abdominal pain, increased stool frequency, loose stools) after receiving adjuvant treatment with 1×108 cfu/kg bw/day of Lactobacillus reuteri JYLB-291, with an effective rate of up to 95.7%.
Lactobacillus reuteri JYLB-291 added to each bag of Huojun No. 1 is not less than 10 billion cfu, which is much higher than the clinical control trial dose of 1×108 cfu/kg body weight. In addition, each bag of Wood No. 1 also contains no less than 10 billion cfu of the star patented strain Lactobacillus casei L.Casei21. This strain can enter the intestine through the digestive tract, inhibit pathogenic bacteria, colonize the intestine, maintain the balance of microflora, improve diarrhea symptoms, and reduce the risk of diarrhea recurrence, and its Chinese invention patent number is ZL 2021 1 0242478.5.
Ulcerative colitis clinical trial II:
A total of 100 patients with symptoms such as abdominal pain, diarrhea, frequent bowel movements, and warmth in the limbs were selected and divided into control and experimental groups, with 50 people in each group, and the trial lasted for 30 days. During the trial, each patient's dietary habits remained the same, and they all took trimerate pudding tablets once a day as instructed by their doctors, while the experimental group took 15 billion Lactobacillus casei21 once a day after taking trimmer maleate tablets for 2 hours. After 30 days, the efficacy was observed and statistically calculated, and the statistical results are shown in the table. It can be seen that Lactobacillus casei L.Casei21 and its products have a significant positive therapeutic effect in patients with diarrhoea, with an overall response rate of up to 92%.
According to the results of the above clinical trials, it can be inferred that since probiotics must first fight against harmful bacteria when regulating the stomach and intestines, and need to go through a period of competition, stalemate, reversal and dominance before they can give full play to their health effects, therefore, after 3 to 6 months of combined medication with Huojun No. 1, ulcerative colitis is expected to achieve full recovery.
Because ulcerative colitis is associated with autoimmune factors, the course of the disease is protracted and difficult to heal, and it is prone to cancer. This is because free radicals attack normal immune cells, making them "abnormal", and these "abnormal" immune cells blindly attack intestinal mucosal cells, triggering inflammation and even forming cancer cells. The theory of free radicals believes that free radicals are the root cause of all evils that cause aging, illness, tumors, and death in the human body, and are also the culprits of autoimmune diseases such as ulcerative colitis, Crohn's disease, and irritable bowel syndrome.
In order to remove excess free radicals from the body, Huojun No. 1 is added with no less than 5 billion star patented strains of Bifidobacterium longum JBLC-141 per bag. This strain can remove excess free radicals in the body, prevent free radicals from causing damage to body cells, and at the same time protect cells from oxidative damage to a certain extent, and relieve body fatigue, its Chinese invention patent number is 202110227019.X. This is of great significance for the prevention of malignant transformation and recurrence of ulcerative colitis.
It is reported that Huojun No. 1 has been put on the shelves of the official flagship store of Jingdong Huojun No. 1, with its "high-end customized enteritis patented formula, five invention patents, pure raw powder without additives and no allergies, the real content of six live bacteria exceeds 50 billion, ultra-active and non-dependent, probiotics special workshop production pollution-free, one company one product ingenuity service" and other seven advantages, won a high degree of user satisfaction, ulcerative colitis "five troika" rehabilitation program, for patients to bring new hope.