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Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

author:Doctor Sanqin

Content Sources:

1. Zhang Hua, Li Ping. Research Progress on Molecular Mechanisms in the Metastasis of Cancer Cells[J]. Chinese Journal of Cancer Prevention and Treatment, 2020, 27(8): 596-602.

2. Chen Ming, Guo Qiang. The role of tumor microenvironment in cancer cell metastasis[J]. Modern Oncology, 2021, 29(2): 350-355.

3. Liu Yang, Wang Xiufang. Research Status and Progress of Circulating Tumor Cells[J]. Chinese Journal of Cancer Research, 2019, 31(1): 48-57.

Sun Yu, a 22-year-old girl from Wuhan, is full of longing for everything in the future, exuding vitality and vitality all over her body, and it seems that her life has just begun to get on track.

However, a routine physical examination completely deviated from the trajectory of her life. When the physical examination report came out the next day, she received a call from the hospital, which said, "Your physical examination report indicates breast cancer, and it is recommended that you come to the hospital for a comprehensive examination and confirmation." "Lingering.

Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

The word breast cancer seemed so far away in her world that when she was diagnosed, Sun Yu found it incredulous. The next day, I went to the hospital again, and after a detailed examination, it was found that it was indeed breast cancer. Perhaps because she was mentally prepared in advance, although she was sad in the face of this result, she did not completely collapse.

After seeing that he was in a slightly calmer mood, the doctor told her that in order to save her life, she had to have surgery to remove her breast as soon as possible. Faced with this sudden blow, Sun Yu fell into despair for a while.

"Do you have to have a mastectomy?" Sun Yu's lips trembled, hoping to get a different answer.

But apparently she didn't receive the answer she was happy with, and the doctor shook his head and said, "This is the best way." ”

Breast cancer is treated with a variety of treatments, including surgery, radiation therapy, chemotherapy, endocrine therapy, and targeted therapy. Among them, surgical treatment is a crucial part of breast cancer treatment, especially in the treatment of early breast cancer.

Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

The main goal of surgical treatment is to completely remove the tumor and reduce the risk of cancer cells metastasizing. For breast cancer patients, the choice of whether or not to have their breasts removed depends on a variety of factors, including the size, location, classification, stage of the tumor, and the patient's personal choice. However, not all breast cancer patients have to have their breasts removed, and in some cases, breast-sparing surgery can be done to remove the tumour while preserving most of the breast tissue.

The reason why breast cancer may have to be removed in some cases is mainly because whole mastectomy may be a more appropriate option when the tumor is large relative to the breast, multiple tumors, the location of the tumor that does not allow enough breast tissue to be preserved for aesthetics, or when the patient is at high risk of recurrence due to the patient's genetic predisposition.

Total mastectomy can significantly reduce the risk of recurrence, and for patients with advanced breast cancer, sometimes not only to control the local pathology, but also to improve quality of life and slow the progression of the disease.

In addition, breast cancer treatment has become increasingly individualized and integrated with the aim of minimizing the impact of surgery while maintaining treatment outcomes.

Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

In practice, many patients can choose a combination of breast-sparing surgery and local radiotherapy. Especially for patients with early-stage breast cancer, this approach can maximize the preservation of the appearance and function of the breast while completely removing the tumor.

However, it is important to note that even after breast-sparing surgery, patients still need to undergo subsequent radiotherapy as well as possibly medical therapy to further reduce the risk of recurrence. Treating breast cancer is a multidisciplinary team process that requires the most appropriate treatment plan for the patient.

After learning of this situation, although Sun Yu was full of reluctance in her heart, in order to survive, she bravely chose surgery.

The operation was very successful, and Sun Yu was quickly discharged from the hospital. But the recovery process after the surgery was not easy, and she had to face a double blow, both physically and psychologically.

However, fate always seems to like to joke with Sun Yu. Just a month later, she was admitted to the hospital again for a check-up because she was unwell, only to be told that the cancer had metastasized and that the situation was even more dangerous than before.

Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

In the face of such a blow, even Sun Yu, who has always been optimistic, began to feel hopeless. The shadow of cancer seemed to hang over her life forever, leaving her feeling like there was nowhere to escape.

But Sun Yu didn't give up. After a brief slump, she began to try to accept this fact and tried to find the possibility of treatment. She began to actively cooperate with the doctor's treatment plan, and also tried to improve her immunity by making lifestyle changes.

But the final result was still not as she expected, and finally she was unable to recover because of the metastasis of cancer cells throughout the body. When he was dying, Sun Yu said: "Why are cancer cells metastasizing so quietly? ”

The truth told by the doctor has something to do with these two factors.

Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

Metastasis of cancer cells is an extremely complex and dangerous stage in the pathogenesis of malignancy, which means that the cancer is no longer confined to the location where it was first discovered, but has spread to other parts of the body through the bloodstream or lymphatic system. The process of metastasis of cancer cells is influenced by a variety of factors, among which lifestyle factors play a non-negligible role. In particular, dietary habits and physical activity have a profound impact on the metastasis of cancer cells.

First of all, dietary habits have a direct or indirect effect on the growth and metastasis of cancer cells. A diet high in fat and sugar can lead to obesity, which is a known risk factor for many types of cancer. Obesity not only causes changes in hormone levels in the body, which promotes the growth of cancer cells, but also causes chronic inflammation, which provides the necessary conditions for cancer cells to metastasize.

In addition, processed foods that contain high levels of additives and preservatives are also thought to be associated with the risk of cancer. Conversely, diets rich in dietary fiber, vitamins, and minerals and foods rich in omega-3 unsaturated fatty acids) can reduce cancer risk, possibly by reducing inflammatory responses, improving immune function, and directly inhibiting cancer cell growth.

Review: After cancer surgery, why do cancer cells metastasize and spread? 2 factors need to be treated with caution

Secondly, physical exercise also has a significant effect on cancer cell metastasis. Regular physical exercise can improve an individual's immunity and enhance the body's ability to eliminate cancer cells, thereby reducing the incidence and mortality of cancer.

Studies have shown that regular participation in aerobic exercise can regulate the activity of immune cells, improve hormone balance in the body, and reduce the risk of obesity, all of which help inhibit the growth and metastasis of cancer cells. In addition, exercise can also reduce the side effects of cancer treatment and improve the quality of life of patients.

In conclusion, a healthy lifestyle, especially a reasonable diet and regular physical exercise, is of great significance to prevent the metastasis of cancer cells. By regulating the functions of various body systems and improving immune status, these measures undoubtedly provide an effective way for cancer prevention and control.