laitimes

Don't sell the medicine to drug dealers, be careful of "good medicine" turning into "poison"丨 Zhou Jian

author:Southern Weekly
Don't sell the medicine to drug dealers, be careful of "good medicine" turning into "poison"丨 Zhou Jian

The National Health Insurance Administration called for cutting off the illegal benefit chain of "reflux drugs". Visual China / Figure

health

[The National Health Insurance Bureau calls for cutting off the illegal interest chain of "reflux drugs"]

On April 26, 2024, the official website of the National Health Insurance Administration issued an appeal: stop selling drugs to drug dealers, and do not buy drugs from unknown sources and damaged packaging.

Many drug dealers induce the insured to buy and sell drugs through "high-price recycling", and these "reflux drugs" have seriously disrupted the normal market order of purchase and sales, and the medical insurance fund that should have been used to save lives has been continuously eaten by a small number of lawbreakers. Through the "black hands" of drug dealers, "good medicine" can turn into "poison".

Jianyan: Direct sales and indirect auxiliary sales of "reflux drugs" are all fraudulent insurance fraud. Cutting off the chain of illegal interests of "reflux drugs" requires everyone to act.

["Perrier" destroys 2 million bottles, suspected to be contaminated with bacteria in feces]

On April 25, 2024, the French Directorate-General for Health said that 2 million bottles of Nestlé's "Perrier" may have been ordered to be destroyed due to bacteria contaminated with feces.

Perrier is Nestlé's brand of sparkling mineral water. On April 27, the relevant person in charge of Nestle responded to the reporter of Nandu Bay Finance Society that the Perrier water that has been delivered to customers and is still sold on the shelves in Nestle, including those sold in China, is safe to drink.

The destroyed Perrier came from a water source near Nîmes, the capital of the Gard department in southern France. On March 10, a routine quality inspection of the water wells at the source revealed the presence of E. coli and Pseudomonas aeruginosa, revealing the "possibility of fecal contamination."

Jianyan: Drinking water safety is no trivial matter. The accident of a well-known "foreign brand" sounded the alarm for the whole industry.

[At present, the epidemic situation of infectious diseases in mainland China is generally stable, and the influenza epidemic situation in some areas has not yet declined]

The Epidemic Prevention and Control Group of the Joint Prevention and Control Mechanism of the State Council recently issued the "Notice on Doing a Good Job in the Prevention and Control of Key Infectious Diseases such as the May Day Holiday in 2024 and the Spring and Summer Novel Coronavirus Infection". The circular pointed out that at present, the epidemic situation of infectious diseases in the mainland is generally stable. The global pandemic caused by the JN.1 variant of the novel coronavirus has passed its peak and has declined to a low level. The prevention and control of some infectious diseases is facing new situations and new characteristics, the influenza epidemic in some areas has not yet fallen back to the level of the same period in previous years, the pertussis epidemic has shown a rapid growth trend, the number of reported cases of hand, foot and mouth disease has increased significantly, and the common epidemic of multiple diseases has become the norm.

Jianyan: During the May Day holiday, the mobility of people increased and the number of gathering activities increased. The public should do a good job of personal protection and health monitoring, pay attention to the dynamics of the epidemic, and actively get vaccinated. During the journey, implement protective measures such as wearing masks scientifically, washing hands frequently, and preventing mosquito bites, and pay attention to food and drinking water hygiene.

Anti-Corruption Chronicle

[A number of medical insurance system officials are under investigation]

On April 22, 2024, it was reported that Zhang Yongyu, Secretary of the Party Group and Executive Vice President of the Fujian Provincial Family Planning Association, is suspected of serious violations of discipline and law, and is currently undergoing disciplinary review and supervision investigation by the Fujian Provincial Commission for Discipline Inspection and Supervision. Zhang Yongyu was a member of the Party Leadership Group and Deputy Director of the Fujian Provincial Health Commission. On the same day, Xu Qingfeng, former member and deputy director of the party group of the Guangdong Provincial Health Commission and former director of the Provincial Bureau of Traditional Chinese Medicine, was expelled from the party and public office for serious violations of discipline and law.

On April 24, it was reported that Jin Jingjing, former secretary of the Party Committee and president of Hainan Provincial Geriatric Hospital, was suspected of serious violations of discipline and law, and is currently undergoing disciplinary review by the Discipline Inspection and Supervision Group of the Hainan Provincial Commission for Discipline Inspection and Supervision of the Provincial Health Commission and the supervision and investigation of the Ding'an County Supervision Committee.

On April 26, it was reported that Liu Zilin, former secretary of the party group and director of the Anhui Provincial Food and Drug Administration, was suspected of serious violations of discipline and law, and is currently undergoing disciplinary review and supervision investigation by the Anhui Provincial Commission for Discipline Inspection and Supervision. On the same day, Duan Yufei, former party secretary and director of the Guangdong Provincial Health Commission, is suspected of serious violations of discipline and law, and is currently undergoing disciplinary review and supervision investigation by the Guangdong Provincial Commission for Discipline Inspection and Supervision.

punish

[A hospital in Jiashan County, Zhejiang Province was punished for suspected decomposition hospitalization and bed hanging]

According to the announcement on the credit Zhejiang website, the Third People's Hospital of Jiashan County, Jiaxing City (a second-class psychiatric hospital) was fined more than 18 yuan for suspected illegal use of medical insurance funds such as decomposition and hospitalization by designated medical institutions. Hospitalization decomposition refers to the medical service provider discharging insured patients who do not meet the discharge criteria and re-admitting them to the hospital for the same disease or the same symptoms in a short period of time, and the diagnosis and treatment process should be completed in one hospitalization for multiple times. Hospitalization in the name (bed) refers to the insured patient who leaves the hospital for a long time or does not actually receive relevant diagnosis and treatment during the hospitalization.

[A hospital in Pan'an County, Zhejiang Province was punished for exceeding the scope of medical insurance payment and excessive diagnosis and treatment]

According to the credit Zhejiang website, the Pan'an County Hospital of Traditional Chinese Medicine (a second-class B traditional Chinese medicine hospital) in Jinhua City was ordered by the Pan'an County Medical Security Bureau to return the medical security fund and impose a fine on suspicion of exceeding the scope of medical insurance payment and excessive diagnosis and treatment. According to the administrative penalty notice, from January 1 to July 31, 2023, Pan'an County Hospital of Traditional Chinese Medicine has six types of medical service items such as "additional collection of disposable sanitary materials", "large, medium and small debridement", "high-risk pressure ulcer prevention and nursing", "blood oxygen saturation monitoring", "acupoint application treatment" and "traditional Chinese medicine rubbing treatment (10% body surface area)", which are suspected of exceeding the scope of medical insurance payment and excessive diagnosis and treatment.

[Two hospitals in Liaocheng City were punished for suspected non-standard medical behavior]

According to the Health Commission of Liaocheng City, Shandong, Liaocheng Traditional Chinese Medicine Hospital (a tertiary hospital) and Luxi Orthopedic Hospital (a non-profit medical institution directly under the city) were fined for non-standard medical practices. Liaocheng Hospital of Traditional Chinese Medicine was fined 10,000 yuan for "using health technicians to engage in medical and health technical work other than their own specialty". In the electronic medical record used by Liaocheng Luxi Orthopaedic Hospital in May 2021, the operation time displayed by the system was inconsistent with the actual time of filling in the medical record, resulting in the non-traceability of information such as previous operation impressions and marked operation times, and was given a warning and a fine of 10,000 yuan.

Jianyan: The medical security fund is the public's "medical money" and "life-saving money", and the hospital's insurance fraud is hidden, and typical cases should be disclosed in the medical system and taken as a warning.

policy

[Further improve the rules for centralized drug procurement]

On April 22, 2024, the heads of the relevant departments of the National Health Insurance Administration and the State Food and Drug Administration answered reporters' questions on standardizing the bidding of entrusted production holders and strengthening the quality supervision of selected drugs in centralized procurement. The person in charge of the Price Procurement Department of the National Health Insurance Administration said that he was concerned about some emerging problems that affect the order of fair competition in the market, such as obtaining additional bidding qualifications, the risk of potential non-standard bidding, and the lack of performance ability, which brought certain challenges to the standardization of drug centralized procurement.

In view of these emerging problems that affect the order of fair competition in the market, the two departments require that the holder should enhance the awareness of the main responsibility, call for the improvement of industry self-discipline, and at the same time, the two departments will continue to optimize the rules for centralized drug procurement organized by the state.

Jianyan: Since 2018, the mainland has promoted the reform of centralized drug procurement, and the centralized procurement of drugs has gradually become normalized and institutionalized, effectively reducing drug prices, reducing the burden on patients, and improving drug accessibility. Centralized drug procurement must ensure fairness, justice, openness and transparency to protect the interests of patients and promote the high-quality development of the pharmaceutical industry.

Previous

[Vitamin D improves anti-cancer immunity by changing intestinal bacteria]

On April 25, 2024, a study published in the top international academic journal Science found that vitamin D can improve the body's immunity to cancer, enhance the effect of immune checkpoint inhibitors, and inhibit tumor growth by promoting the growth of an intestinal bacterium, Bacteroides fragilis. This study reveals the role of the gut microbiota in cancer immunity and the potential of dietary interventions to provide the possibility of cancer prevention and treatment.

Advice: Many people are deficient in vitamin D, but the way to supplement it is simple. Exposure to the sun and food is also rich in vitamin D in marine fish, liver, egg yolks and lean meats.

【AI-Assisted Drug R&D】

On April 24, 2024, Moderna, a global mRNA giant, and OpenAI, an emerging AI giant, announced that they are working together to promote AI+ healthcare. According to Moderna, AI technology is embedded in every part of the company's business, including law, research, manufacturing, and commercialization, which helps employees do their jobs. Stéphane Bancel, CEO of Moderna, believes that just as the introduction of personal computers in the 1980s changed the way people work and live, artificial intelligence is revolutionizing everyday life.

Jianyan: On the C-side, large models in the medical industry are currently hot, and many technology companies have launched related products, so that patients can consult AI doctors. On the B side, AI also empowers pharmaceutical companies to improve R&D and productivity. The application prospects of AI in the medical field are full of imagination.

[The world's first case of a 54-year-old female patient transplanting an artificial heart and a pig kidney at the same time]

According to a report on the official website of New York University Langone Health Center on April 24, 2024, surgeons at the center performed the first combined surgery of a mechanical heart pump (LVAD) and a gene-edited pig kidney transplant. Lisa Pisano, a 54-year-old female patient in the United States, suffers from end-stage heart failure and kidney failure, diabetes, colon cancer, and has high levels of "harmful antibodies" to human tissues. The center's Robert Montgomery team decided to implant Pisano with a left ventricular assist device followed by a pig kidney transplant. None of the patients showed signs of organ rejection for 13 days after surgery and had good kidney function.

In March 2024, the world's first pig kidney transplant was performed at the Massachusetts General Hospital in the United States, and the patient recovered well after surgery. Does the success of the second case of pig kidney transplantation herald the arrival of a new era of pig kidney transplantation and even a new round of xenotransplantation research?

Medicines

[Changshan Pharmaceutical's marketing authorization application for ebenatitide injection was accepted]

On the evening of April 24, 2024, Changshan Pharmaceutical announced that the marketing authorization application for ebenatide injection developed by Changshan Kaijiejian Biodrug R&D (Hebei) Co., Ltd., a holding subsidiary of the company, has been accepted by the National Medical Products Administration. Ebenatitide is a class 1 innovative drug with a proposed indication for improving glycemic control in patients with type 2 diabetes.

[FDA approves Breakthrough Therapy for the treatment of non-muscle-invasive bladder cancer that does not respond to BCG]

On April 22, the U.S. FDA approved Anktiva, an interleukin-15 (IL-15) super agonist developed by Altor Bio Science, a subsidiary of Immunity Bio, in combination with Bacillus Calmette-Guérin (BCG) for the treatment of adult patients with non-muscle-invasive bladder cancer who do not respond to BCG and have carcinoma in situ, with or without papillary tumors.

capital

[The top 20 global pharmaceutical companies in terms of revenue are released, and Johnson & Johnson ranks first on the list]

Recently, the American pharmaceutical website Fierce Pharma released a list of the top 20 pharmaceutical companies in the world by revenue in 2023, with Johnson & Johnson, Roche, and Merck ranking among the top three. Johnson & Johnson's 2023 annual sales reached $85.2 billion, a year-on-year increase of 6.5%. Pfizer, which ranked fourth, fell 41% from $100.3 billion in 2022 to $58.5 billion due to declining sales of the new crown vaccine Comirnaty and the new crown antiviral drug Paxlovid.

【Huadong Medicine HDM1005 Injection Drug Clinical Trial Application Approved by the US FDA】

Huadong Medicine announced that recently, the company's wholly-owned subsidiary, Zhongmei Huadong, received a notice from the US FDA that the clinical trial application for HDM1005 injection drug declared by Zhongmei Huadong has been approved by the US FDA, and phase I clinical trials can be carried out in the United States, and the indication is weight management in adults who are overweight or obese.

Southern Weekly reporter Lin Fangzhou and Southern Weekly intern Wang Qixin

Editor-in-charge: Wang Tao