Painkillers and ibuprofen, both of which are common medications in our daily lives to relieve various pain symptoms. However, they differ significantly in composition, mechanism of action, and use.
Pain Relief Tablets, as an over-the-counter drug, its main ingredients include aminopyrine, phenacetin, caffeine, and phenobarbital. Together, these ingredients can effectively inhibit the synthesis of prostaglandins in the body, thus achieving an analgesic effect.
At the same time, analgesic tablets also have antipyretic, anti-inflammatory and anti-rheumatic effects, and have significant effects on relieving mild to moderate pain, such as headaches, toothaches, joint pain, etc.
Ibuprofen, on the other hand, is a non-steroidal anti-inflammatory drug (NSAID), which inhibits cyclooxygenase in the body and reduces the synthesis of prostaglandins, thereby exerting analgesic, anti-inflammatory and antipyretic effects.
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Ibuprofen is widely used in clinical practice to treat various pains, such as dysmenorrhea, muscle pain, joint pain, etc. In addition, it is well tolerated and has relatively few side effects, making it popular with patients.
Although both analgesic tablets and ibuprofen have a certain role in analgesia, their composition and mechanism of action are different, so the choice of use needs to be judged on a case-by-case basis.
For mild pain, such as headache, toothache, etc., painkillers may be a good choice, while for moderate to severe pain, such as arthritis, dysmenorrhea, etc., ibuprofen may be more suitable.
01
The difference between painkillers and ibuprofen
First of all, from the perspective of drug properties, analgesic tablets belong to compound preparations, which mainly contain aminopyrine, phenacetin, caffeine and phenobarbital. Ibuprofen, on the other hand, is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic, and antipyretic effects.
Secondly, there are also significant differences in the mechanism of action between the two. The aminopyrine and phenacetin in analgesic tablets mainly play an antipyretic role by inhibiting the synthesis and release of hypothalamic prostaglandins, restoring the normal reactivity of thermoregulatory central sensory neurons, and can also play an analgesic role by inhibiting the synthesis of prostaglandins.
Caffeine, as a central stimulant, is able to enhance the analgesic effect of the first two. However, long-term use of analgesic tablets may have certain side effects, such as vomiting, rash, fever, profuse sweating and stomatitis, and a small number of patients may also have severe symptoms such as neutropenia, aplastic anemia, erythema exudative, exfoliative dermatitis, and glans erosion.
In contrast, the mechanism of action of ibuprofen is mainly by inhibiting cyclooxygenase and reducing the synthesis of prostaglandins, resulting in analgesic, anti-inflammatory effects. It acts as an antipyretic through the hypothalamic thermoregulatory center.
The advantage of ibuprofen is that it has relatively few side effects and is less irritating to the gastrointestinal tract. However, it may still cause some adverse effects, such as gastrointestinal symptoms such as nausea, vomiting, stomach burning, or mild indigestion, as well as headaches, tinnitus, blurred vision, nervousness, drowsiness, edema of the lower limbs, or sudden weight gain, among others.
In terms of application, analgesic tablets are mainly used for fever and mild and moderate pain, while ibuprofen is more used to relieve mild to moderate pain, such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, dysmenorrhea, etc. In addition, ibuprofen can also be used for fever caused by the common cold or influenza.
02
Pain tablets or ibuprofen, which has the biggest side effects on the human body?
Pain relievers and ibuprofen are two common medications that can be used to relieve mild to moderate pain such as headaches, joint pain, toothache, etc. However, many people are not clear about the size of the side effects of these two drugs on the human body.
First of all, we need to be clear that any drug has the potential to have side effects, depending on individual differences, drug dosage, duration of medication, and other factors. Pain relievers and ibuprofen are no exception.
As an over-the-counter drug, the main ingredients of analgesic tablets include aspirin, caffeine, etc., which have a certain gastrointestinal irritating effect, and long-term use in large quantities may lead to gastric ulcers, bleeding and other problems. In addition, painkillers may also cause uncomfortable symptoms such as allergic reactions and itchy skin.
As a non-steroidal anti-inflammatory drug, the side effects of ibuprofen are mainly manifested in the impact on the gastrointestinal tract. Long-term use in large quantities may lead to gastrointestinal bleeding, ulcers and other problems, and in severe cases, it may even be life-threatening. In addition, ibuprofen may also cause headaches, dizziness, nausea and other uncomfortable symptoms, and some people may also have allergic reactions.
In summary, both painkillers and ibuprofen have the potential to have certain side effects, and each has certain risks. Therefore, when choosing a drug, we should consider it comprehensively according to our own situation, the drug instructions and the doctor's advice, and avoid blind use.
03
Take painkillers safely and keep in mind 4 precautions
First of all, it is necessary to prescribe the right medicine. Different types of pain require different types of pain medications. For example, for mild pains such as headaches or toothaches, we can opt for over-the-counter painkillers such as aspirin or ibuprofen.
However, for more severe pain, such as arthritis or post-operative pain, a prescription medication from a doctor may be required. Therefore, when choosing painkillers, we must be clear about the cause and type of pain and choose the most suitable drug.
Secondly, the dosage and timing of administration should be followed. The use of painkillers must be done strictly in accordance with the instructions or the doctor's advice. Overdose or long-term use may result in drug dependence, side effects, or physical injury. In addition, we should also take our medication on time and do not change the time or dosage of medication at will.
Third, be aware of drug interactions. Many medications can interact with painkillers, causing them to be less or more effective, or even to produce harmful substances. Therefore, when taking painkillers, we should inform our doctor about other medications we are taking to ensure safe use between medications.
Finally, focus on how your body reacts. After taking painkillers, we should pay close attention to our body's reactions. If you experience any discomfort or abnormal symptoms such as nausea, vomiting, dizziness, etc., you should stop the medication immediately and seek help from your doctor.
In addition, long-term use of painkillers may lead to drug resistance in the body, so we should regularly evaluate the effectiveness of the drug and adjust the medication regimen in time.