55-year-old Uncle Wang was diagnosed with high blood pressure, hyperlipidemia and coronary heart disease five years ago, in order to control the condition, the doctor prescribed him statins and told him once a day, but Uncle Wang had his own ideas, it turned out that Uncle Wang learned from the Internet that the side effects of statins are very large, and there is a risk of causing myolysis and liver damage.
Uncle Wang decided to take statins every other day, which could not only control the condition, but also reduce side effects.
Uncle Wang felt that his decision was perfect, but he ignored a very important reality, that is, it is difficult for him to form a stable drug concentration when he takes medicine like this, and without a stable drug concentration, it is almost impossible to control the condition.
However, Uncle Wang fell into his own habitual thinking, so he insisted on it for five years, until one day, he suddenly felt severe chest pain, his family saw that he was pale, sweating profusely, realized that the situation was wrong, and hurriedly dialed 120 for help, twenty minutes later, Uncle Wang was sent to the emergency department, through examination, the doctor determined that Uncle Wang had suffered from acute myocardial infarction.
The doctor said, you found high blood pressure, hyperlipidemia and coronary heart disease five years ago, didn't you use the medicine?
Uncle Wang said, I have been taking medicine, blood pressure medicine, statins, and aspirin, and I don't understand, why does my condition worsen?
In fact, the doctor found that although Uncle Wang had been taking medicine for a long time, his blood pressure and blood lipids were not well controlled at all.
Through careful questioning, the doctor finally found out the reason, although Uncle Wang has been taking medicine for a long time, he has played a clever trick, and these drugs are only taken once every other day.
It is useless to take medicine like this.
Statins, i.e., 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors, can not only strongly reduce total cholesterol (TC) and low-density lipoprotein (LDL), but also reduce triacylglycerol (TG) to a certain extent, and can also increase high-density lipoprotein (HDL).
Commonly used statins include simvastatin, atorvastatin, pravastatin, rosuvastatin, and many more.
Statins are generally taken once a day, and are basically taken at night.
Only by insisting on taking the medicine for a long time can a stable concentration of the drug be formed, if you fish for three days and dry the net for two days, then it is impossible to have a good effect.
1. What are the side effects of statins?
Clinical manifestations of statin-associated myopathy include myalgia, myositis, rhabdomyolysis, and liver damage, so it is important to watch closely for abnormal signals while taking statins.
When there is unexplained myalgia, oliguria, and soy sauce urine, it is necessary to be alert to the possibility of myolysis, and if there is loss of appetite, oil aversion, fatigue, jaundice, etc., it is necessary to be alert to liver damage.
Before taking statins, be sure to check the liver and kidney function, for patients with obvious liver and kidney abnormalities, it is not suitable to take, even if there is no liver and kidney abnormality, it does not mean that it will not appear during the medication, so the liver and kidney function should also be closely monitored during the medication.
2. During the period of taking the drug, do not increase or decrease the amount of medicine without authorization
Some patients feel that their condition is very serious and think that statins need to be increased to control the condition, and some patients feel that the side effects of the drugs are too great, so they reduce the dose of drugs without authorization, which are actually the wrong way to take the drug.
The dose of statin must be taken gradually, and the amount of the drug should also be strictly controlled, unless the doctor actively advises you to increase the dose of the drug, do not increase it without authorization, so as to avoid unknown risks.