Adults' fears always start from reading the physical examination report, especially when they see the words "nodules, cysts, and hyperplasia", and they can't help but "chuckle" in their hearts.
In addition to being frightened, many people can't help but wonder, why do "foreign bodies" such as nodules, cysts, and hyperplasia suddenly appear in a good body? Will they become cancerous? What should I do if I encounter them? Today, Xiao Jiu will explain to you clearly at one time.
In fact, these "foreign bodies" do not appear suddenly, but are the products of the accumulation of various factors such as genetics, environment, and unhealthy lifestyle.
Inflammatory reactions caused by environmental pollution, chemical exposure, bacterial or viral infections may lead to significant proliferation of fibrous tissue, and the gradual formation of cysts and nodules.
Modern people are addicted to alcohol and prefer spicy, high-fat, high-sugar foods, and these poor eating habits will further promote the inflammatory response.
It can be said that inflammation is the "catalyst" for the production of foreign bodies such as nodules, affecting the occurrence and development of these symptoms. At the root of this, studies have found that defects in autophagy are the "culprits" of inflammatory responses.
Autophagy is a homeostatic mechanism in the human body in which cells initiate cellular pathways to remove damaged proteins, organelles, or invading pathogens in response to stress, in order to maintain the stability of the cell's internal environment.
Literally, it means "eating yourself", providing nutrients and energy by "eating" your own non-essential ingredients, while also degrading some toxic components to stop cell damage and apoptosis.
In 2016, Japanese scientist Yoshinori Ohsumi was awarded the Nobel Prize in Medicine for his discovery of the regulatory mechanism of autophagy and the biological role behind it, revealing that autophagy plays an important role in the occurrence and development of immunity, infection, inflammation, tumors, cardiovascular diseases, neurodegenerative diseases and other diseases.
Autophagy has a variety of regulatory mechanisms in the inflammatory response. Autophagy can not only inhibit inflammasome aggregation by degrading endogenous stimuli such as intracellular DNA and reactive oxygen species, but also degrade interleukin (L)-IB precursors to inhibit the secretion of pro-inflammatory factors such as TL-)B, thereby exerting anti-inflammatory functions. In addition, autophagy can also attenuate the inflammatory response by promoting the clearance of apoptotic cells.
Normally, autophagy regulates the inflammatory response through these mechanisms and maintains homeostasis in the body, but if the body has autophagy deficiency, it will lead to uncontrolled excessive inflammatory response, increasing the chance of "foreign bodies" and diseases in the body.
But you don't have to worry too much, most of the nodules, cysts and hyperplasia are benign.
Nodules: mostly benign
Nodules are round, oval, or irregularly shaped lesions left over from various inflammatory or non-inflammatory lesions in the body. Thyroid nodules, breast nodules, and pulmonary nodules are common, but most are benign.
In the case of thyroid nodules, for example, more than 85% are benign. Thyroid nodules can be treated according to the TI-RADS classification, categories 1-3 are basically benign and can be rechecked regularly, and the risk of malignancy in category 4 and above gradually increases, so it is necessary to see a doctor as soon as possible.
However, it should be noted that if the nodule continues to grow, there is also a possibility of cancer, so it needs to be reviewed regularly, and the doctor can give an overall judgment on the risk of nodule based on factors such as nodule morphology, clinical manifestations, and personal medical history.
Hyperplasia: Not necessarily harmful, but there is one type to be aware of
Hyperplasia is divided into physiological and pathological causes, but pathological hyperplasia does not mean that it will become cancerous. For example, breast hyperplasia is mostly physiological, mainly affected by endocrine hormone metabolism, usually pay attention to adjust the life and rest, maintain a happy mood, and combine drug treatment if necessary.
However, it is important to watch out for prostatic hyperplasia. Because it is easy to cause abnormal urination, symptoms such as frequent urination, urgency, time-consuming and laborious urination, and with the aggravation of hyperplasia, it will seriously affect the quality of life of patients, so it should be actively examined and treated.
Cysts: Most leave it alone
A cyst is like a "blister", a benign lesion that generally does not have much impact on health. For example, liver cysts, as long as the cyst does not have symptoms of compression on the surrounding organs, or inflammation and infection, it is basically ignored. Complications, such as ruptured cysts and intracystic hemorrhage, require surgery.
Although we don't need to be overly anxious about these "small problems" on the physical examination report, we can't ignore it, after all, there is still the possibility of cancer. In order to avoid the further development of these symptoms, it is recommended to carry out the following preventive and maintenance measures on a daily basis.
Based on the mechanism of autophagy, it has become one of the important methods to reduce the occurrence and development of diseases by activating autophagy and reducing inflammatory response.
In recent years, more and more studies have found that spermidine, curcumin and other ingredients are natural activators of autophagy.
Taking spermidine as an example, it is a natural polyamine that can induce autophagy, inhibit the activation of inflammation-related signaling pathways, and regulate the degree of inflammatory response by inhibiting the release of inflammatory mediators and downregulating the level of antioxidant stress. Curcumin also has antioxidant properties, which help neutralize free radicals, reduce cell damage caused by oxidative stress, and protect cells from oxidative stress.
Therefore, in order to reduce the probability of inflammation, you can supplement spermidine, curcumin and other nutrients for daily health care, and you can also take Xinsen No. 3, which contains spermidine + quercetin + curcumin + coenzyme Q10 four compound ingredients, which work together to activate the autophagy mechanism of cells, clean up harmful substances in the body, and reduce the risk of disease. It is worth mentioning that the production plant of Xinsen Health Care is located in Hong Kong and the United States, and has been certified by the FDA, and the product quality is guaranteed and trustworthy.
If the doctor highly suspects or confirms malignant nodules, hyperplasia, etc., further treatment is required. Generally, the diagnosis of cancer at the nodular stage is mostly at an early stage, and if it has not metastasized, surgical resection is usually recommended, and if metastasis has occurred, it needs to be combined with other treatment methods at the same time.
Most of the nodules, cysts, and hyperplasia found in the physical examination are benign, and there is no need to worry too much about them in daily life, but they should not be ignored, but they should be paid attention to, followed up on time, and checked regularly, including color ultrasound, MRI, enhanced CT, etc., and biological biopsy if necessary.
Bad lifestyle habits such as irregular diet, irregular work and rest, and lack of exercise are important stimuli for nodules, cysts and other diseases, so it is necessary to pay attention to life conditioning, ensure adequate sleep, maintain a balanced diet, quit smoking and drinking, and insist on exercising.
In addition, long-term psychological stress can lead to endocrine disorders and increase the risk of disease. Timely relief of mood and avoidance of anxiety and depression are also important means of prevention.
Source: 39 Health Network
Editor: Huang Ting
Duty Director: Yuan Yuzi
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