Regenerative oral fluid
Clinical use is often combined with chemotherapy, radiotherapy, targeted therapy, immunotherapy, etc., which can effectively improve the short-term efficacy of patients, reduce the rate of tumor recurrence and metastasis, improve the quality of life of patients, and reduce the occurrence of adverse reactions such as chemotherapy, radiotherapy, and immunotherapy.
Below, Xiaobian will take you to the Chinese patent medicine Huisheng oral liquid used for primary liver cancer and lung cancer.
【Source of the group】
The composition of Huisheng Oral Liquid originates from Wu Jutong's "Differentiation of Warm Illness" Volume 1: Huahui Shengdan. The Huisheng Pill is made of the addition and subtraction of the "Golden Kui Yaolu" turtle nail decoction pill and the "Rejuvenation of Ten Thousand Diseases".
【Composition of the drug】
Motherwort, safflower, Sichuan pepper (charcoal), leech (made), angelica, sumac, triangular (vinegar), two-pointed tip, Chuanxiong, incense, incense (vinegar), ginseng, galangal, turmeric, myrrh (vinegar), bitter almond (fried), rhubarb, perilla seeds, cumin (salt-fried), peach kernels, Wuling grease (vinegar burned), fly insects, turtle shells, cloves, Yanhusuo (vinegar burned), white peony, puhuang (charcoal), frankincense (vinegar burned), dry lacquer (calcined), Evodia (licorice boiled), ferul, cinnamon, mugwort leaf (burned), rehmannia rehmannia (burned). The excipients are polysorbate 80 and cyclamate.
【Rebirth Solution】
Medicine: Motherwort, turtle beetle.
"Compendium of Materia Medica" Motherwort "travels blood without hurting blood, nourishes blood without stasis"; Turtle carapace: nourishes the yin of the liver and kidney, and has the functions of invigorating blood, removing blood stasis, diluting water, softening and firmness, and removing stasis without harming righteousness.
Medicine: leech, flyworm, puhuang, five lingzhi, dry lacquer, peach kernel, safflower, Chuanxiong, Yanhusuo, Sanleng, frankincense, myrrh, sumac, incense, rhubarb, turmeric. For "if you don't make it, it hurts".
Zuo envoy: Rehmannia rehmannia, ginseng, angelica, white peony and other twelve flavors. It is designed for "no glory is pain", and it is set up to correct and dispel evil.
【Indications】
It is used for primary liver cancer and lung cancer.
【Dosage】
Take 10-20 ml orally three times daily or as directed by a healthcare practitioner.
1. It can be taken at the same time as internal medical treatment;
2. If there is no bleeding, use Huisheng oral solution as soon as possible before and after admission to the hospital until 1 day before surgery. Directions: Oral, 20 mL/time, 2 times/day.
3. Eliminate bleeding and continue to take Huisheng oral solution from 3 days after surgery to 1 month after surgery. Directions: Oral, 20 mL/time, 3 times/day
【Mechanism of action】
It inhibits the proliferation, growth and metastasis of tumor cells by acting on the WNT pathway, and improves the hypercoagulable state and inflammatory state by regulating the tumor microenvironment.
【Regenerative Distribution】
1. Invigorate blood and eliminate symptoms
Because blood stasis is an important factor in the pathogenesis of tumors, it is not only the initiating factor of accumulation, but also due to the compression and invasion of surrounding tissues by the mass, which can lead to the aggravation of blood stasis. When the treatment is to dispel stasis and eliminate symptoms, it is compatible with frankincense, myrrh, loss of laughter (Wuling fat, Puhuang), Yanhusuo, peach kernel, motherwort, safflower, angelica, etc.
2. Ventilation machine
Blood and qi are mutually reborn, interdependent, and have a very close relationship, known as "qi is the handsome of blood, and blood is the mother of qi". In terms of pathology, qi disease can hurt blood, and blood disease can also hurt qi: if the qi is not smooth, the blood flow is unfavorable, and the unfavorable blood flow will aggravate the qi stagnation.
3. Dissolve phlegm and clear the channels
Phlegm and dampness are yin and evil, heavy turbidity and stickiness, stagnation in the meridians, easy to inhibit the qi, and cause unfavorable blood flow and stagnation of the veins. Tumors are mostly manifested as body surface or subcutaneous lumps, and traditional Chinese medicine mostly treats them from phlegm, so they are equipped with Suzi, almonds, and two-headed tips to promote and lower qi and dissolve phlegm.
4. Make up for the deficiency and correct it
"Deficiency" is not only an important factor in the onset of accumulation, but also the inevitable result of the development of accumulation. Almost every patient with hypertrophy, in the middle and late stages of the disease, often has fatigue and fatigue, low voice, five heart irritability and other manifestations of qi and yin deficiency, so the treatment of hypertrophy, in the practice of qi and blood, phlegm and elimination of symptoms at the same time, should pay attention to the right and dispel evil, with ginseng to replenish qi and strengthen the spleen, turtle nails to nourish yin and latent yang, white peony, rehman, angelica, Chuanxiong (i.e., Siwu soup) to replenish blood and invigorate blood, and play the function of qi and yin double supplementation, qi and blood double supplementation. The turtle shell in the square is unique, not only nourishing the yin of the liver and kidney, but also being soft and hard.
Clinical application
1. Anti-tumor
Primary liver cancer, lung cancer, esophageal cancer. Interfere with cancer cell DNA synthesis, damage cancer cell DNA template, induce cancer cell apoptosis and affect cell cycle, and regulate the immune function of body cells.
2. Relieve cancer pain
Compared with the therapeutic effect of Huisheng oral liquid and morphine hydrochloride on pain, the results showed that when the drug was administered within 1 hour, due to the different routes of administration, the analgesic effect of morphine hydrochloride was better than that of Huisheng oral liquid, but when the medication time was extended to 2 hours or more, it could be found that the analgesic effect of the two was close to that of Huisheng oral liquid, and with the extension of time, Huisheng oral liquid showed a trend of gradual strengthening of analgesic effect.
3. Improve blood hypercoagulability
A perioperative multi-center RCT study of lung cancer was carried out, and it was found that Huisheng oral solution could significantly improve the platelet count, FIB content, and D-dimer content of patients, and the use of 20ml of tid showed no adverse reactions in patients with no increased bleeding risk.
4. Inhibit tumor neovascularization
Reducing the formation of cancer thrombus can effectively inhibit pulmonary thrombosis and lung metastasis caused by Lewis lung cancer in C57 rats, and the mechanism of action is related to improving the coagulation and fibrinolysis abnormalities of malignant tumors, inhibiting angiogenesis of tumor tissues and enhancing immunity.
5. Improve the quality of patients and prolong survival
A large number of literatures have proved that it has obvious advantages in improving the quality of life of patients, relieving cancer pain, improving constipation, improving curative effect, and prolonging survival.
Precautions
- Do not use in pregnant women
- People with allergies should take with caution
- Shake well before serving
Author: Liu Kaifei, pharmacist in charge of Jingzhou Central Hospital
Reviewer: Yang Yuanrong, Chief Pharmacist, Department of Pharmacy, Jingzhou Central Hospital, and Xiong Jianqun, Deputy Chief Pharmacist