Statins and aspirin do play a very important role in the prevention of cardiovascular and cerebrovascular diseases. But you can't watch others eat and follow along, you must grasp the indications, because both statins and aspirin have side effects.
As long as someone has high blood pressure and vascular plaque, they take aspirin. For many years, many doctors have recommended that people over the age of 70 take aspirin as long as they have high blood pressure, diabetes, and atheroma in the carotid arteries, but the risks far outweigh the benefits.
Because although aspirin can reduce the risk of myocardial infarction and stroke, because the side effects of aspirin are also obvious, long-term use by the elderly may cause the risk of gastrointestinal bleeding and cerebral hemorrhage, and this side effect is more serious and even life-threatening.
Therefore, the use of aspirin must be based on the indications, and it is only used for the secondary prevention of coronary heart disease, post-stroke, peripheral vascular occlusion, etc., to prevent recurrence. It is not recommended for patients who do not have cardiovascular and cerebrovascular diseases, but simply have high blood pressure, diabetes, and carotid plaque.
It should be noted that the older the age, the higher the risk, and pay attention to whether there is hematuria, black stool, epigastric pain and other manifestations during use.
If it is used with antiplatelet and anticoagulant drugs such as clopidogrel, ticagrelor, and rivaroxaban, it should be closely observed. When taking aspirin, if it is combined with non-steroidal anti-inflammatory analgesics, such as ibuprofen, diclofenac sodium, celecoxib, etc., and glucocorticoid prednisone, the risk of gastrointestinal bleeding will also increase significantly.
Some people exaggerate the side effects of statins, and not taking them when they should also cause aggravation of atherosclerosis.
In fact, statins play a very important role in fighting atherosclerosis, stabilizing vascular plaque, and preventing acute myocardial infarction and cerebral infarction.
Of course, statins also have certain side effects, but as long as they are detected in time, they can basically be avoided.
For example, it causes an increase in aminotransferases. The main effect of this statin is to inhibit the synthesis of cholesterol in the liver, which may cause an increase in liver enzymes. Therefore, if it is only a mild increase, there is no need to reduce the drug, just pay attention to observation, if it is more than 3 times, the drug needs to be stopped, and most of them can return to normal.
For those who have high blood lipids and elevated liver enzymes caused by fatty liver, a statin with less liver damage, such as rosuvastatin, can be started at a small dose and repeated.
Statins also have the side effect of muscle damage. Causes myalgia, myositis, but rhabdomyolysis is extremely rare.
Therefore, it is important to check the level of creatine kinase, and if you have myalgia but the muscle enzymes are not high, you can continue to take the drug if the symptoms are not severe. Water-soluble statins such as rosuvastatin generally improve symptoms, but if creatine kinase is elevated more than 10 times, the drug needs to be discontinued for observation.
Statins generally do not harm the kidneys. Statins have anti-renal arteriosclerotic effects and can also protect the kidneys, which can cause acute kidney injury only in severe rhabdomyolysis.
When taking statins orally, also be aware of the possibility of new-onset diabetes. For obesity, prediabetes, the elderly, etc., who are prone to mild elevation of blood sugar, the regular dose of statin has little effect on blood sugar, and the benefits of statin anti-atherosclerosis can offset the impact of elevated blood sugar.
To sum up, both statins and aspirin have side effects, but they will have great benefits when used well, statins can lower cholesterol, stabilize atherotic plaque, and even reverse plaque, effectively reducing the occurrence of cardiovascular disease. Aspirin can prevent blood clots for high-risk people.
Compared with the two, statins have a greater effect, and if the plaque is stabilized and does not rupture, there will be no blood clot formation, and aspirin will not play a role. #他汀类药物 ##阿司匹林#
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