Aminotransferases are important enzymes found in the liver, heart, and muscles, and they play a role in the body that converts amino acids into energy and oxidizes fatty acids to carbon dioxide and water. The activity of transaminases is essential for the maintenance of normal physiological functions in the human body.
There are many types of aminotransferases, the most typical of which are alanine aminotransferase (GPT) and aspartate aminotransferase (GOT). GPT is mainly found in the liver, and when the liver is damaged, GPT is released into the bloodstream, so it is possible to tell if the liver is damaged by measuring the level of GPT in the blood. GOT is mainly found in the heart and muscles, and when the heart or muscles are damaged, GOT is also released into the bloodstream.
The activity of aminotransferases is affected by a variety of factors, including diet, exercise, drugs, alcohol, viral and bacterial infections, etc. For example, long-term alcohol consumption can damage liver cells, leading to increased GPT levels, while excessive exercise can lead to muscle damage that can increase GET levels.
The detection of aminotransferases is one of the common biochemical tests in clinical practice. By measuring the levels of aminotransferases, doctors can determine whether the liver, heart or muscles are damaged and take appropriate treatment measures.
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For example, in patients with hepatitis, doctors monitor GPT levels to assess the condition and response to treatment, and in patients with heart disease, doctors monitor GOT levels to determine heart function and disease progression.
01
What does it mean that the "aminotransferases" in the physical examination report are high?
First, we need to understand the normal range of aminotransferases. In general, the normal value of transaminases should be between 0-40 units per liter.
If it is outside of this range, it means that there may be a problem with the liver or skeletal muscles. Therefore, when the aminotransferase value is high on the physical examination report, it is necessary to pay attention to it and consult a doctor in time.
Doctors point out that high levels of aminotransferases can be due to liver disease. For example, diseases such as hepatitis, cirrhosis, and liver cancer can cause transaminase levels to rise. In addition, factors such as long-term alcohol consumption, drug side effects, and excessive fatigue may also cause damage to the liver, resulting in high levels of aminotransferases.
In addition to liver problems, skeletal muscle disease can also cause high aminotransferases. For example, skeletal muscle diseases such as polymyositis and muscle injuries can cause elevated aminotransferase levels. In addition, factors such as strenuous exercise and overwork may also cause damage to skeletal muscles, resulting in high levels of aminotransferases.
02
What is the association between aminotransferases and liver disease?
Aminotransferases are an enzyme that is vital in the human body and is mainly found in liver cells. Aminotransferases are released into the bloodstream when liver damage or disease occurs, so measuring transaminase levels in the blood can help doctors diagnose liver disease.
Aminotransferases play an important role in the occurrence and progression of liver disease. When the liver is damaged, aminotransferases within liver cells are released into the bloodstream, causing transaminase levels to rise.
Different types of liver disease can cause elevated levels of different types of aminotransferases. For example, acute hepatitis may cause elevated alanine aminotransferase (ALT) levels, while chronic hepatitis may cause elevated aspartate aminotransferase (AST) levels.
In addition to hepatitis, other liver diseases can cause elevated aminotransferase levels. For example, diseases such as fatty liver, cirrhosis, and liver cancer can cause abnormal aminotransferase levels. These diseases can cause damage to liver cells, which allows transaminases to enter the bloodstream.
In addition to testing aminotransferase levels, your doctor may do other tests to help diagnose liver disease. For example, liver ultrasound, liver biopsy, and liver function tests, among others, can help doctors understand the morphology and function of the liver so that liver disease can be better evaluated and treated.
03
What should I do if aminotransferases are abnormally elevated?
First of all, it is necessary to seek medical attention in a timely manner. Abnormally elevated aminotransferases may be a manifestation of diseases such as hepatitis, cirrhosis, and liver cancer, which require professional treatment and management. Therefore, if you find that aminotransferases are abnormally elevated, you must seek medical attention in time and receive professional diagnosis and treatment.
Secondly, pay attention to your diet and lifestyle habits. The liver is an important metabolic organ of the human body, and poor diet and lifestyle habits can cause damage to the liver.
Therefore, it is necessary to maintain a healthy diet, eat more vegetables and fruits, and reduce the intake of greasy, spicy and other irritating foods. At the same time, it is necessary to ensure adequate sleep and proper exercise, and avoid overexertion and staying up late.
In addition, it is necessary to avoid indiscriminate use of drugs and health supplements. Many drugs and supplements need to be metabolized by the liver, and if the liver is damaged, these drugs and supplements may increase the burden on the liver.
Therefore, it is important to consult a doctor before taking any medication or health supplement to avoid unnecessary damage to the liver.
Finally, keep a positive mindset. Mood swings and psychological stress can take a toll on liver health. Therefore, it is important to learn to regulate your emotions and maintain a positive mindset and optimistic mood, which is very important for liver health.
04
Aminotransferases are elevated, what foods do you eat to drop quickly?
First and foremost, high-protein foods are ideal for elevated aminotransferases. Fish, lean meats, legumes, and other foods are rich in high-quality protein, which can provide the amino acids needed for liver repair and help the liver function better. At the same time, protein also has the effect of promoting liver cell regeneration and improving liver function.
Secondly, vitamin-rich foods are also a good helper for lowering aminotransferases. In particular, antioxidants such as vitamin C and vitamin E can help scavenge free radicals and reduce the burden on the liver. Fresh vegetables, fruits, nuts, etc. are all excellent sources of vitamins.
In addition, some Chinese herbs also help to lower transaminases. For example, schisandra, wolfberry, salvia, etc. all have hepatoprotective, enzyme-lowering, and antioxidant effects, and can be consumed in moderation under the guidance of a doctor.
It is worth noting that when transaminases are elevated, bad eating habits such as excessive alcohol consumption and eating greasy foods should be avoided so as not to increase the burden on the liver.
At the same time, dietary therapy is only an adjunct and cannot replace professional medical treatment. If aminotransferases are persistently elevated, it is necessary to seek medical attention promptly for professional diagnosis and treatment.
In short, for the problem of elevated aminotransferases, we can start with the diet, choose high-protein, vitamin-rich foods and some Chinese herbal medicines that have a liver-protective effect. At the same time, maintaining a good diet and lifestyle can better protect liver health.