Born in the late Eastern Han Dynasty, the "Shennong Baicao Jing" recorded such a substance: "The Lord supports life, responds to the sky, lightens the body and improves qi, increases wisdom and wisdom, and can be presented with high quality." ”
In the thousands of years of history of traditional Chinese medicine, Ganoderma lucidum has been regarded as the treasure of traditional Chinese medicine. Back in modern times, mainland scientists have found that the methyl ganodeate E (MGE) rich in Ganoderma lucidum, after being absorbed by the body, can improve the resistance to various allergens, rewrite the aging phenotype, and even reduce the aggregation of aging markers.
The research was jointly completed by the Chinese Academy of Sciences, the Guangxi Academy of Sciences and the University of Nigeria, and the relevant results have been published in the journal Food & Function.
01. Ganoderma lucidum extract, inverted life 26%
Many studies using model organisms such as Caenorhabditis elegans, Drosophila, and mice have shown that bioactive compounds can regulate the aging pathways of living organisms through a variety of pathways, such as flavonoids in pomegranates, AAW in mugwort leaves, and 6-gingerene in ginger, which have been published in top journals such as Nature and Aging.
Scientists have extracted more than 160 active compounds from Ganoderma lucidum, and after evaluating 74 of them one by one, it was finally found that when 10 μg/ml methyl ganodeate E was used to treat Caenorhabditis elegans, the following changes occurred in the organism:
(1) showed greater resistance to hydrogen peroxide (a strong oxidant), (2) significantly reduced amyloid-β (a marker of Alzheimer's disease) aggregation, and (3) increased survival by up to 26%.
Aging is a process of gradual loss of physiological integrity, and this decline is a major risk factor for human disease. Although scientists have made a lot of progress in the research of model organisms, there are still uncrossed gaps before these results can be translated into human anti-aging technologies. Fortunately, people's understanding and exploration of life are leaping forward at an astonishing speed.
At the beginning of this year, the journal Cell published 12 markers of aging, including loss of protein homeostasis, dysregulation of nutrient perception, and cell exhaustion, which affect each other and confirm that aging is a process that must be considered as a whole.
The TimeCure management plan, developed by the domestic TimeCure health intervention team based on "aging will affect the whole body", took the lead in starting from internationally recognized aging markers, and incorporated a large number of technologies from physiological index determination, nutrition program customization, cell inversion, etc.
According to a financial practitioner who booked the TimeCure service on the official website of TimeCele, this service not only includes the neurofilament light chain (NFL) that can predict Alzheimer's disease 16 years in advance, the customized nutrition line certified by the GMP factory, but also the 1.9 atmosphere micro-hyperbaric oxygen chamber known as the "civil ceiling", the -180 °C freezer cabin, and the N-in-one optical chamber that reaches the cell layer and can improve the metabolism of the whole body and other cutting-edge equipment.
02. Harvard professor: 90% of life expectancy is the result of daily intervention
David Sinclair, a professor of biological genetics at Harvard, said in an interview with Australia's magazine The Monthly: "Genes determine less than 10% of human lifespan, and more than 90% is the result of daily interventions." He was named one of the 100 Most Influential People in the World by Time Magazine for his contributions to the field of aging.
According to his sharing on his personal social platform, the management methods including hyperbaric oxygen chamber, diet adjustment, light chamber cold therapy, and nutrition customization are impressively listed, and Sinclair, who is now 54 years old, has an actual biological age of only 43 years old after being measured.
Similarly, by clicking on the appointment window of the official website of Timepai, you can find that the management methods favored by high-net-worth individuals, such as equipment experience, 11 basic nutrition tests and health risk assessments, are all in line with Sinclair's listed methods, and it seems to be at the forefront in terms of comprehensiveness and technological upgrades.
For example, the pressure value of foreign hyperbaric oxygen chambers is mostly 1.1 to 1.3 pressure values, compared with the 1.9 pressure values of TimeCure, there is no research to confirm that the pressure is less than 1.5 The cabin is effective;
The above-mentioned 58-year-old financial practitioner, Mr. Zeng, was "reversed" by 6.5 years in one year after receiving the management of TimeCure. "The numbers are real, and now with my friends, everyone jokes that it doesn't look like an age group. According to the backstage appointment data on the official website, most of the people who come to consult are groups in first-tier cities such as Beijing, and there is no shortage of inquiries such as "can you make an appointment for your 70-year-old parents" and "can you intervene early at the age of 28".
03, the mystery of aging, will be unobstructed?
As Professor Sinclair put it, "Death is inevitable, and how we grow old should be our choice." "With the continuous advancement of science and technology, whether it is a variety of anti-aging substances or a series of customized management methods provided by TimeCure, we have more choices in the face of aging.
However, it should be noted that in subsequent experiments, when the researchers treated it with 50 μg/ml and 200 μg/ml concentrations of methyl ganodeate E, the life length of Caenorhabditis elegans did not change significantly, which also reflects that it is still debatable to rely on Ganoderma lucidum to reverse aging, how to control the dosage and ensure the stability of the effect outside the experiment.
Before scientists completely solve the puzzle of "aging without decay", with the help of more comprehensive and comprehensive means supported by data, with the help of a research team such as Timepie, which focuses on aging technology, may be a better choice to fight against time.