Inflammation is a natural response of the body's immune system to a foreign pathogen. When the body is stimulated by an infection, injury, or allergen, the immune system releases inflammatory mediators that trigger a cascade of physiological responses to eliminate pathogens and promote tissue repair.

Inflammation can be divided into two types: acute inflammation and chronic inflammation. Acute inflammation usually manifests as redness, swelling, heat pain, and local tissue dysfunction, accompanied by systemic reactions such as fever and leukocytosis.

Chronic inflammation is usually long-lasting, insidious, and often manifests as tissue hyperplasia, fibrosis, and dysfunction.

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50% of deaths are related to "inflammation"? German study: inflammation that occurs at a young age can be harmful for a lifetime

Moderate inflammation is a normal response of the body, which can improve the body's local resistance and the ability of tissue cells to repair. However, if the inflammation persists for a long time, the body will be overly defensive, which can have adverse effects on health, and this damage may accompany the person throughout his or her life and even induce a series of diseases.

A study published in the journal Cell by the German Cancer Research Center and other teams found that inflammatory stimulation reduced hematopoiesis by conducting experiments on mice. After several injections of the stimulator, which can cause short-term aseptic inflammation, the researchers recovered after 4 weeks, and the number of mature blood cells in the stimulated mice did not change significantly, but the clonogenic ability and proliferative potential of hematopoietic stem cells decreased significantly.

Hematopoietic stem cells are the origin of hematopoietic cells and immune cells, and when their function decreases, they can affect the normal hematopoietic function of the body. In addition, the researchers also found that the cumulative damage to mouse hematopoietic stem cells by inflammatory stimulation was irreversible.

After one year of follow-up, they found that the number of hematopoietic stem cells in the inflammation-stimulated group was reduced by about 20 times compared with the control group, and the more stimulation times, the worse the hematopoietic ability became. In addition, researchers have found that inflammation accelerates cellular aging.

They examined the levels of epigenetic modifications in mice and found that the genetic age of the mice in the stimulus group was greater than the biological age, implying that inflammation is a driver of accelerated aging. The results of the study show that if the middle and young people are affected by inflammation, the injury is likely to accompany the person for a lifetime, and even affect the hematopoietic system in old age.

50% of deaths are related to "inflammation", which should be taken seriously

A study in the journal Nature Medicine revealed that diseases associated with chronic inflammation have become one of the leading causes of death, accounting for up to 50% of mortality rates. In addition, studies have also found that if the human body is in a state of chronic inflammation for a long time, the risk of death will be greatly increased. This suggests that the threat of chronic inflammation to human health cannot be ignored.

Inflammation sows the seeds very early

Associated with cancer

A prolonged inflammatory state can leave the immune system in a state of confusion, like a band that has lost its conductor and is unable to accurately identify and remove tumor cells.

For example, Helicobacter pylori, an uninvited guest, once it settles in our stomach, it will cause gastritis, and if left untreated, gastritis may gradually evolve into stomach cancer. This process is like a small stone slowly rolling down and eventually turning into a mountain.

Induces cardiovascular disease

The disorder of the immune system is like the outbreak of a civil war, making the otherwise peaceful blood vessel walls a battlefield, and the inflammation takes advantage of the weakness to wreak havoc. The walls of blood vessels become fragile and even broken due to inflammation.

The broken blood vessel wall is like a rag that cannot withstand the impact of blood, and plaque gradually forms in the blood vessel, blocking the normal flow of blood. More seriously, these plaques can also form blood clots, like silt blocking rivers, leading to serious diseases such as coronary heart disease.

Plant the seeds of diabetes

In the development of diabetes, the inflammatory response acts as a stealth destroyer, quietly eating away at endothelial cells in blood vessels and tissues through oxidative stress mechanisms. These endothelial cells, which were once loyal guards to protect our blood vessels and tissues, have suffered heavy losses in this invisible war.

Their damage not only weakens the transport and absorption of insulin in tissues, but also triggers a series of chain reactions that eventually lead to the emergence of insulin resistance.

Damage to the nervous system

When the inflammatory response gets out of control, it creates neurotoxicity that causes damage to neuronal cells. It's like an out-of-control flame, and in the brain environment of Alzheimer's patients, astrocytes and microglia release inflammatory factors that act as accelerants and further accelerate the degeneration of neurons. It's like a wildfire raging across the prairie, mercilessly burning precious nerve cells.

Increase the risk of obesity

Adipose tissue not only acts as a storehouse of energy, but also hides important elements such as macrophages. Once there is excessive fat accumulation, excess fat cytokines are released, which ignites the fire of chronic inflammation throughout the body.

The macrophage infiltration of adipose tissue invisibly exacerbates this quiet chronic low-grade inflammatory state. Because of this, obesity is no longer just a physical posture, but is taken seriously as a disease, often accompanied by the shadow of many complications.

Increased risk of depression

During the onset of depression, like a small war within the body, inflammatory cytokines are released and the inflammatory response becomes abnormally active.

For people with depression, they not only suffer from an increase in inflammatory factors, but also cope with an increased inflammatory response. It's like a shadow that can't be shaken off that always accompanies them and makes them feel endless pain and distress in the depths of their hearts.

How long does it take for inflammation to become a big cancer?

The transformation of inflammation into cancer is a complex process that involves many factors, including the severity and duration of inflammation, the age of the patient, genetic factors, and lifestyle, among others. Therefore, the time at which inflammation transforms into cancer is uncertain, and there is no one specific answer.

In general, long-term chronic inflammation may increase the risk of cancer. This is because the inflammatory response can promote cell proliferation and neoangiogenesis, processes that are critical steps in tumorigenesis and progression. However, not all inflammation develops into cancer. The relationship between inflammation and cancer needs to be further studied and explored.

For pre-existing inflammatory diseases, such as gastritis, enteritis, etc., they should be actively treated and controlled to reduce the risk of them developing into cancer. In addition, maintaining good lifestyle Xi, such as eating a healthy diet, exercising moderately, quitting smoking and limiting alcohol, can also help reduce the risk of inflammation and cancer.

In conclusion, the time at which inflammation transforms into cancer is uncertain and related to a variety of factors. We should actively prevent and control the occurrence and development of chronic inflammation while maintaining good lifestyle Xi to reduce the risk of inflammation and cancer. For pre-existing inflammatory diseases, they should be actively treated and controlled to maintain good health.

Doctor: Try not to delay the three types of inflammation

[From gastritis to stomach cancer]

The early symptoms of stomach cancer are quite similar to gastritis and are often difficult to detect. They can cause symptoms such as indigestion, pain in the upper abdomen, feelings of fullness, anemia, and anorexia. It's like being in a dark fog, silently invading our health. Therefore, when the body has symptoms similar to gastritis, we should be vigilant and actively seek treatment.

If we ignore the initial symptoms of gastritis and allow it to develop, then gastritis may evolve into chronic gastric ulcers, atrophic gastritis, and even hyperplasia with abnormal intestinal metaplasia. It's like reefs lurking in our sea of health, and once touched, it can cause huge waves.

From hepatitis to liver cancer.

Chronic hepatitis such as hepatitis B, hepatitis and hepatitis C are like a shadow that creeps in, gradually eroding the health of the liver. They are hidden allies of liver cancer, silently planting the seeds of a malignant disease in their bodies. When these chronic hepatitis entangles the liver, it will cause deep or shallow damage to the liver tissue, like a delicate painter leaving a flaw on the canvas.

If these diseases are not eliminated in time, the liver may gradually lose its original vitality and resilience over time, and gradually wither like a dehydrated flower. Over time, the liver may develop into cirrhosis, which is a prelude to liver cancer and the twilight of a healthy liver. If left untreated, this process may be like an avalanche, which can get out of control and eventually lead to liver cancer.

【From cervicitis to cervical cancer】

Cervical cancer, this little-known ruthless killer, has quietly claimed the lives of countless women. However, cervical inflammation is not the same as cervical cancer, and there is no inevitable causal relationship between them. For those cervical inflammation caused by gonorrhea and chlamydia infection, as long as we help in time, they will not collapse on the road of no return to cervical cancer.

However, when we are confronted with cervical inflammation caused by the HPV virus, if we sit idly by, they may approach the abyss of cervical cancer.

Inflammation control starts with 5 things

First and foremost, eating right is key. Choosing foods rich in antioxidants, such as dark vegetables, fruits, and nuts, can help fight inflammation. At the same time, reduce your intake of high-sugar, high-fat, and processed foods, which may exacerbate inflammation.

Secondly, regular exercise can help improve blood circulation and promote the resolution of inflammation. Getting at least 150 minutes a week of moderate-intensity aerobic exercise, such as brisk walking, cycling or swimming, can help reduce inflammation levels.

Third, getting enough sleep is also essential. Studies have shown that sleep deprivation increases inflammatory markers in the body. Therefore, adults should get 7 to 9 hours of sleep per night.

Fourth, stress reduction and psychological adjustment are equally important. Long-term stress and anxiety can lead to chronic inflammation, so learning to relax and adjust your mindset is essential to manage inflammation. Try relaxation techniques like meditation, yoga, or deep breathing to relieve stress.

Finally, avoiding tobacco and alcohol is also an important measure to control inflammation. Smoking and excessive alcohol consumption can exacerbate inflammation, and staying away from these bad Xi can help reduce the level of inflammation in the body.

In short, by starting from the five aspects of diet, exercise, sleep, stress reduction, quitting smoking and limiting alcohol, we can effectively control the level of inflammation in the body and maintain good health. Incorporate these healthy lifestyles into your daily life to build a solid foundation for your health.