Hand sanitizer has become an indispensable daily necessity for cleaning and disinfection in daily life, what are the bacteriostatic active ingredients of anti-bacteriostatic hand sanitizer on the market? I'll summarize it to you today.
1: Ethanol (alcohol)
Hand sanitizers with ethanol as the main bactericidal component are generally hand sanitizers or hand gels. A certain concentration of alcohol solution can denature the protein in the bacteria and achieve good disinfection and sterilization purposes. Usually based on ethanol hand gel, the content of ethanol is generally 55%-80% or combined with other bacteriostatic ingredients. For example, the ethanol content of drip hand sanitizer is 55%-65%.
2: 4-Chlorodimethylphenol (PCMX)
P-Chlorodimethylphenol (PCMX) is a highly efficient, broad-spectrum, soft and low-toxic fungicide with a white needle-like crystalline appearance and characteristic odor of halophenols. PCMX is currently the main bacteriostatic ingredient in most brand hand sanitizers. Usually the amount added is 0.1%-0.5%. For example, the dosage of PCMX is 0.1%-0.3% of the pure white fragrance hand sanitizer, and the dosage of Velux Health Antibacterial Hand Sanitizer PCMX is 0.15%-0.2%.
3: 0-Phenylphenol
0-Phenylphenol, also known as o-phenylphenol, is a white or light yellow or reddish powder, flake or lump with a faint phenolic taste. 0-Phenylphenol has a broad spectrum of sterilization and mildew removal capabilities, and is low toxicity and odorless, and is commonly used in bacteriostatic hand sanitizers, usually adding amounts of 0.15%-0.5%. Blue Moon Aloe Vera Bacteriostatic Hand Sanitizer is 0.16%-0.2% w/w with the addition of 0-phenylphenol.
4: Triclosan
Triclosan has an aromatic high purity white crystalline powder and is a broad-spectrum antibacterial agent. It has the following advantages: (1) fragrant high-purity white powder, not contaminated with products and skin; (2) soluble in a variety of organic solvents and surfactants; (3) highly stable to strong acids and alkalis and heat; (4) no irritation to the skin; (5) high efficiency broad-spectrum antibacterial effect. Because of the above advantages, triclosan is widely used in bacteriostatic hand sanitizers, and the recommended concentration is 0.05% to 0.3%. For example, Kaimi, Amway, and Kennosu bacteriostatic hand sanitizers have all been used.
5) Salicylic acid
Salicylic acid is a fat-soluble organic acid that is a white crystalline powder with antiseptic and bactericidal effects. It is used less in hand sanitizer, and the common one is that the dosage of drip moisturizing double health hand sanitizer is 0.24%-0.36% w/w.
6: Benzalkonium chloride
Benzalkonium chloride is a white waxy solid or yellow colloid and is a quaternary ammonium-based cationic surfactant. Benzalkonium chloride is a broad-spectrum fungicide that can change the permeability of the bacterial cytoplasmic membrane, make the cytoplasmic substance of the bacterial body extravasate, hinder its metabolism and have a killing effect. In addition, benzalkonium chloride as a cationic surfactant also has foaming, emulsification, decontamination and other effects. Typically used in hand sanitizers is the drip foam hand sanitizer series dosage of 0.08%-0.12% w/v.
7) Piroctone ethanolamine salt
Piroctone ethanolamine salt is a white or light yellow crystalline powder and is a fungicide. The substance has been identified by foreign authoritative institutions as very reliable for the safety of the eyes and skin. Absolutely non-toxic, irritating and allergenic, it is generally used as a desquamant. However, it is also used for bacteriostatic hand sanitizers, such as Shufujia's healthy bacteriostatic hand sanitizer, which is used in an amount of 0.18%-0.22 (w/w).
8: Botanical herbs (mugwort, calendula, tea fruit, licorice, peony peel, etc.)
Typical applications are: Green Umbrella Antibacterial Foam Hand Sanitizer is used for plant extracts such as tea fruit, licorice, peony peel, etc.; Liushen Hand Sanitizer uses plant herbs such as mugwort and calendula.
9: Other.
For example: polyhexamethylguanidine, complex alcohols and the like
Although there are many kinds of bacteriostatic ingredients in hand sanitizers, our actual production process must consider cost, availability, replicability and so on. After comprehensive consideration, choose the bacteriostatic ingredient that suits your own formulation.
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