From the beginning of the 18th century, rats began to enter the laboratory.
Just started with research in different types of experiments, such as liver, skin, and blood cells, all of which will be very helpful for biomedical research. First, being able to grow inside mice could help us create better mouse models to study human disease. We've used mice to study human diseases, and it's not always as accurate as we would like to be when we genetically mimic the symptoms of these diseases, for example, if these animals have human cells and human DNA, should we treat them differently than normal animals, and the method of culturing cells in mice won't replace traditional cell culture. Growing our stem cells and mice could be a way to realize the prospects they represent.
Mice play an important role in the testing of many disease drugs, and 95% of experimental animals are mice and rats. According to the Biomedical Research Foundation, there are many reasons to experiment with mice. The first thing you see is that the rats are very small and therefore easy to manage. They reproduce quickly and have a short lifespan of only 2-3 years, so several generations of mice can be observed in a relatively short period of time. Rats are also relatively inexpensive and can be bought in large quantities from commercial producers dedicated to research. These rodents are usually gentle and docile. This makes it easier for researchers to deal with them. Most of the mice used in medical trials were raised with bread, so they were genetically identical except for sex differences. This helps to make the results of medical trials more uniform. According to the Human Genome Institute as a minimum requirement. Mice used for the experiment must be the same pure red variety. Another reason mice are used as models in medical tests is because their genetic, biological, and behavioral traits are remarkably similar to those of humans, and they have many symptoms. Can be replicated in mice and rats. Rats and mice are mammals that share many processes with humans and are suitable for answering many research questions. Over the past 20 years, these similarities have become more pronounced. Scientists now have access to genetically altered minds known as genetically modified mice, which carry genes similar to those that cause disease in humans. Similarly, the selected gene can turn off or make an active creation knockout mouse, which can be used to assess the effects of cancer, causing a response to assess drug safety!
But in order to effectively grow human stem cells, for research purposes, you have to grow a lot of infected human stem cells to implant in mouse embryos to see if they will develop the same. The researchers found more than 70 percent of the transferred embryos. Human stem cells were indeed cultured for research.
So what can we do to grow better human stem cells? As a solution, perhaps it is to grow our stem cells with mice, not petri dishes.
Also, most of the DNA is similar to humans. They suffer from many diseases like humans, such as cancer, diabetes and even anxiety. Studies of mice help scientists understand. Causes of many different diseases.
Mice have the same number of genes as humans, and about 85 percent are the same. Almost all human genes are associated with this. So, it's still important for cancer research, and tens of millions of mice have played a central role in science for nearly 200 years. Do a job they don't like, a job that almost always leads to early death.