The reaction process of aerobic oxidation of sugars
There are three phases:
Glycolysis pathway: glucose pyruvic acid
Pyruvate acetyl CoA
(1) Pyruvate oxidative decarboxylation to form acetyl-CoAPyruvate Is Oxidized to Acetyl-CoA and CO2,
The multi-enzyme complex is located in the mitochondria
Prokaryotic cells are in the cytosol.
Pyruvate dehydrogenase system: E1-pyruvate dehydrogenation / carboxylase (component)
E2-Dihydrohethionyl-toacetylase
E3-Dihydroheuric acid dehydrogenase;
Six cofactors: TPP, lipoic acid,
CoA-SH、FAD、NAD+、Mg2+。
Pyruvate dehydrogenase complex
Citric Acid Cycle of Citric Acid
Citric Acid Cycle
Tricarboxylic Acid Cycle
Krebs loop
In the aerobic eukaryote mitochondrial matrix or aerobic prokaryote cytoplasm, the fermentation product pyruvate is decarboxylated, dehydrogenated, thoroughly oxidized to CO2, H2O and produced ATP.