How is desloratadine used? Super-full usage summary is coming

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01 Chronic idiopathic urticaria

1.1

Adult (Domestic)

▎1.1.1 Indications

Used to relieve symptoms associated with chronic idiopathic urticaria [1-5].

▎1.1.2 Dosage

Orally, 5 mg once daily. Eating does not affect the effect of taking the drug [1-5].

Dispersible tablets are added to an appropriate amount of water when used, stirred evenly and dispersed, or taken directly with water [4].

The suspension is dissolved in water and stirred well before serving, which can be taken at the same time as food [5].

1.2

Adults (FDA)

▎1.2.1 Indications

Tablets are indicated for relieving pruritus symptoms in patients with chronic idiopathic urticaria aged 12 years and older, reducing the number and area of urticaria [6].

Oral solutions are indicated for relieving pruritus symptoms in patients with chronic idiopathic urticaria of 6 months and older, reducing the number and area of urticaria [8].

▎1.2.2 Dosage

The recommended dose of tablets is 5 mg once a day. Eating does not affect the effect of taking the drug [6].

The recommended dose for oral solution is 10 ml (containing 5 mg of desloratadine) once daily [8].

02 Allergic rhinitis

2.1

▎2.1.1 Indications

Used to relieve systemic and local symptoms of allergic rhinitis [1][3].

▎2.1.2 Dosage

Orally, 5 mg once daily. Eating does not affect the effect of taking the drug [1][3].

03 Perennial allergic rhinitis

3.1

▎3.1.1 Indications

It is used to relieve the systemic and local symptoms of perennial allergic rhinitis[2][4][5].

▎3.1.2 Dosage

Orally, 5 mg once daily [2-5].

The suspension is soluble in water, stirred well before serving, and taken with food [5].

3.2

▎3.2.1 Indications

Tablets are indicated for the relief of symptoms in patients aged 12 years and older with perennial allergic rhinitis [6].

Oral chipping tablets are indicated for relieving symptoms in patients aged 2 years and older with perennial allergic rhinitis [7].

Oral solutions are indicated for relieving symptoms in patients with perennial allergic rhinitis for 6 months and older [8].

▎3.2.2 Dosage

The recommended dosage for tablets is 5 mg once daily, regardless of food factors [6].

The recommended dose for oral chipping is 5 mg once daily [7].

04 Seasonal allergic rhinitis

4.1

▎4.1.1 Indications

Tablets are indicated for the relief of symptoms in patients with seasonal allergic rhinitis 12 years of age and older [6].

Oral chipping tablets are indicated for relieving symptoms in patients aged 2 years and older with seasonal allergic rhinitis [7].

Oral solutions are indicated for relieving symptoms in patients with seasonal allergic rhinitis 2 years of age and older [8].

▎4.1.2 Dosage

bibliography:

[1] Drug information: desloratadine tablets, import drug registration certificate number H20140450;2019/12/05.

[2] Drug information: desloratadine capsules, Chinese medicine standard H20138004;2015/09/18.

[3] Drug information: desloratadine syrup, Chinese medicine standard H20100009;2010/11/09.

[4] Drug information: desloratadine dispersible tablets, Chinese medicine standard H20040972.

[5] Drug information: desloratadine dry suspension, National Pharmaceutical Standard H20041111;2017/06/08.

[6] Product Information: DESLORATADINE tablet, Virtus Pharmaceuticals, Updated October 25, 2020.

[7] Product Information: DESLORATADINE tablet, orally disintegrating, Dr. Reddy's Laboratories Limited, Updated March 20, 2019.

[8] Product Information: CLARINEX- desloratadine tablet, film coated,CLARINEX- desloratadine solution, Merck Sharp & Dohme Corp. Updated January 27, 2021.

Source: Clinical Decision Assistant

Editor-in-charge: Zheng Huaju

Proofreader: Zang Hengjia

Plate making: Xue Jiao