Recently, Professor Brian Kennedy, who is quite prestigious in the field of aging in Singapore, published an article in the well-known academic journal "Aging", pointing out that the human body has been 8 years younger by 7 months by giving AKG intervention, indicating that the quality and length of human life will benefit from this, and declaring that it will not be biased towards those rich.
7 months younger and 8 years younger, healthy survival period is stretched
Professor Brian Kennedy, who was in charge of the experiment, introduced the details, they decided to use AKG as a test intervention after a lot of screening, and used it to observe the effect on the mice, and found that the survival time of the mice was stretched by 5% to 10%, and the energy was improved by 50% compared with the original, and many attenuation indicators were optimized, including hair quality. The improvement of the indicator of weakness means that the ability to resist disease can be greatly improved, and there will be a longer healthy survival period.
Based on the study, Professor Brian Kennedy conducted deeper human trials of AKG. They selected 42 adults, including 28 and 14 men and women, with an average age of 63 years. After 4-10 months of intake testing, the experimental team members concluded that they were "8 years younger" after physiological testing.
AKG has not been found to be harmful to the human body
According to publicly available information, various current studies have shown that AKG does not harm humans. Scientists have also conducted a large-dose intake trial of 6 grams per day, and the participants did not develop discomfort, and before its core mechanism of action was excavated, bodybuilders and exercisers mainly used it to gain muscle, and for a long time.
However, from the analysis of the results of the experiment, the substance did achieve the stretching of the survival period of the experimental object, but the experiment also had some improvements, such as only 42 participants in the test, and the sample was too small. In addition, there is no comparison between the control group and the observation group in the experiment, so the response to this experiment is more popular, and the academic community has not reacted too much to it.
For Professor Brian Kennedy, AKG, as one of the intermediate substances in the human tricarboxylic acid cycle, will show an age-related decline, and its decline is similar to that of another important factor, NAD, so the human body needs to be replenished to bring it back to the level of twenty or thirty years old. However, the mechanism of action of AKG in this regard needs more experiments to support it.
In contrast, the research on the mentioned NAD anti-aging molecule is relatively mature, and the direct precursor of the molecule can be replenished, which can improve the mitochondrial activity, energy supply, etc., thus playing a positive role in aging. The University of Tokyo, Guangzhou Sport University, etc. experimented with it and obtained results that were consistent with expectations. The finished product "Wlnad" has landed in China through the East, and The Rich Lee's has spent 200 million yuan on similar investments, and after trying it himself, he has lamented that the maturity of the substance may become a reference model for AKG.
The tech dividend should not be reduced to the exclusive privilege of the rich
With the rapid development of the field of biology, the scientific research community has produced many results with different mechanisms, and they once had the same drawback - the high cost of use. In 2020, Israeli scientists discovered the principle of "high-pressure oxygen inhalation", 3 months younger than 25 years old in the experiment, and the hyperbaric oxygen chamber O2ark born of this became popular, but its pricing of more than 300,000 made ordinary people prohibitive. The earlier popular "blood exchange" in North America, the elderly rich replace the blood from 18-25-year-old young people, for which it costs more than 200,000 yuan each time, 4 times a year, and lasts for 3 years, calculating that it will be more than 3 million.
Professor Brian Kennedy has his own opinion on this, saying that his research serves the people, not the rich, and he wants everyone to get a lifespan gain from it. Therefore, if the AKG substance can be practically applied in the future, the cost of use will not be too high, most people will be able to afford it, and then consider that there will be no discomfort, which can be said to be worth looking forward to.
However, this experiment is still insufficient, and it can only be said that it has a good prospect. And "WLnad" such stretch life supply, the use of costs - east also reduced by more than 95%, the biotechnology company "LiteVigian" said that with the further improvement of production capacity, it is possible to achieve the use of the threshold of further exploration in the future.
Nowadays, aging has become a common problem, the length of life stretched by science and technology is not only the research direction of scientists, but also to meet the needs of social development, it is understood that the core of "Wlnad" has been listed as an important research project by the neighboring Japanese scientific research circle, which is aimed at the increasingly obvious degree of aging in the local area.
For most of us, the relevant technology that benefits human life expectancy should not only be for the rich, but also for more ordinary people to enjoy, so it is a very important thing to lower the threshold of use and popularize it.