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Assessment of blood selenium levels in humans and influencing factors

author:Xibaikang selenium science

The assessment of blood selenium levels in the human body is usually based on the total amount of selenium in blood, urine, hair and other tissues; it is related to the content of selenium in soil, diet, and disease state.

Assessment of blood selenium levels in humans and influencing factors

1. Do you know the similarities and differences between blood selenium, hair selenium, and urinary selenium measurements?

Human selenium levels are generally assessed by the total selenium content of blood, hair, urine and other tissues, in which the selenium content of blood and urine can be used as a monitor of the body's selenium level in real time, and will change in real time with the daily intake of selenium content and the time when selenium preparations enter the human digestive tract. Due to the relatively long growth process of the hair, it represents the average selenium level of the body over a period of time, which is relatively stable as a long-term indicator; In addition, due to the convenience of sample collection and the fact that it is not easy to interfere with the subject, it can be dynamically monitored and other advantages, and it has also been widely used in the study of selenium levels in the human body.

2. What is the relationship between human sun exposure levels and soil?

Assessment of blood selenium levels in humans and influencing factors

Since 2008, among the more than 20 longevity townships in China, the longevity townships with the characteristics of the largest area, the largest population and the most balanced distribution of life stars have received more attention. In 2008, the Institute of Geography of the Chinese Academy of Sciences (now the Institute of Geographical Sciences and Natural Resources Research) drew a map of the distribution of five longevity belts in China, namely: The Bama-Du'an-Donglan Longevity Belt in Guangxi, the Sanshui-Foshan Longevity Belt in Guangdong, the Dujiangyan-Pengshan Longevity Belt in Sichuan, the Luxi-Menghai Yijinghong Longevity Belt in Yunnan, and the Aktao-Aksu-Turpan Longevity Belt in Xinjiang, all of which have higher soil selenium content. The blood selenium level in the body of the long-lived elderly is generally 3 to 6 times that of normal people, and the selenium is more than 50% higher than that of normal people

3What problems can human blood selenium levels cause?

Yu Shuyu et al. randomly detected the level of residents in 24 regions of 8 provinces in China, studied its relationship with cancer mortality, and found that blood selenium levels were inversely correlated with cancer rate, and the incidence of esophageal cancer, gastric cancer and liver cancer in low selenium areas was significantly higher and higher, and the incidence of middle selenium was significantly higher. Tissue selenium levels in cancer patients are significantly lower than subnary A, while alcoholics have the lowest levels of dirty selenium. It can be seen that diseases as well as ethanol crude affect the level of selenium in the body.

4What problems can low selenium levels cause in humans?

Assessment of blood selenium levels in humans and influencing factors

Selenium deficiency can produce many endemic diseases, such as Keshan disease, which was first discovered in Heilongjiang Province, China, in 1935, and large osteoarthritis with slow-entropic joint deformity as the main pathological feature in developing children with chondrogenesis necrosis. Selenium deficiency in the local and internal environment is closely related to the onset of both, the lower the selenium level, the more serious the disease, selenium level and the disease is significantly negatively correlated. Selenium is also closely related to cataracts, and selenium deficiency is prone to the occurrence of cataracts. Low selenium intake increases the incidence and mortality of chronic diseases, and selenium supplementation worldwide is expected to reduce the overall incidence of cancer. In short, the lack of selenium in the human body can cause structural and physiological abnormalities in different tissues. Selenium supplementation prevents such abnormalities and normalizes dysfunction and structure.

5. How to increase selenium levels in the human body?

Assessment of blood selenium levels in humans and influencing factors

Through drugs, health care products and foods, the level of selenium in the human body can be increased. In China's "Standard for the Use of Food Nutrition Enhancers" (GB148012), the amount of reinforcement is calculated by the content of elemental selenium: dairy products, cereals and their products are 140~280ugkg, and milk powder for children is 60~130ugkg Milk-containing beverages are 50200ug/kg; The compounds that can be used as selenium nutrition enhancers are sodium selenite, sodium selenate, selenoprotein, selenium-rich edible mushroom powder, L selenium methyl selenium cysteine, selenium carrageenan, selenium-rich yeast and so on. The dietary supply recommendations for selenium revised by the National Conference on Nutritional Science range from 60 to 250 g per day

Supplementing L-selenium is to directly supplement L-selenium cysteine, selenoidine is the best, but selenium cysteine is difficult to exist in its natural state and is directly oxidized. So add methylation to it, that is, L-selenium methyl selenium cysteine, from the perspective of biochemistry experts, into the human body directly remove a methyl group, it is metabolized, this is the most direct supplement, which is simpler and more direct than plant selenium supplementation than animal selenium supplementation. Then the absorption rate of selenium in the body is 100% absorbed. At present, scientific research believes that the digestive tract has no obstacle to this selenium, as long as the selenium we eat, the selenium ingested in food, no matter what form, as long as the selenium we ingest in the body 100% into the bloodstream, and then through the portal vein into the liver, and then into the body metabolic circulation.