Gastric mucosal protectors can strengthen the defense function of the gastric mucosa, can play a positive role in the healing of ulcers, and are one of the basic drugs for the treatment of peptic ulcer and gastroesophageal reflux disease. At present, there are many gastric mucosal protectors, and their mechanism of action and taking time are different, and most of them are related to meal time, and cannot be generalized.
Image source: Figureworm Creative
01
Aluminum magnesium carbonate tablets
Magnesium aluminum carbonate is both a mucosal protector and an antacid, which can adsorb pepsin, bind bile acids, and stimulate the gastric mucosa to increase the synthesis of prostaglandin e2, thereby enhancing the barrier function of the gastric mucosa.
Magnesium aluminum carbonate antacact acts quickly, the effect is mild and long-lasting, and due to the combination of bile acids, it has a good effect on bile reflux gastritis.
Aluminum magnesium carbonate contains two metal ions, aluminum and magnesium, which cancel each other out the adverse reactions of constipation and diarrhea, but it should be noted that the two metal ions of aluminum and magnesium can interfere with the absorption of a variety of drugs such as tetracyclines, iron, quinolones, anticoagulants, digoxin, ranitidine, etc. When taking, the time must be staggered.
▌ Dosage: Chew 1-2 hours after a meal, chew 1-2 tablets before going to bed or when the stomach is not in a hurry.
02
Sucralfate suspension
Sucralfate can bind to positively charged proteins on the ulcer surface to form a protective barrier; adsorb bile salts and bile acids to prevent gastric acid and pepsin erosion; complex with pepsin to inactivate pepsin. It can be used in the treatment of peptic ulcers.
▌ Directions: Take 1 hour before meals and before bedtime, 2-4 times a day, 5-10 ml at a time.
03
Tipridone capsules
Tipuridone can directly increase mucus secretion and promote cell regeneration, thereby alleviating the damage to the gastric mucosa, and can restore the damaged gastric mucosa and even ulcers, which has a direct protective effect on the gastric mucosa.
▌ Directions: Take after meals (bioavailability is significantly increased compared to taking on an empty stomach), three times a day, one capsule at a time.
04
Compound glutamine granules
Compound glutamine granules are a compound formulation consisting of sodium benzosulfonate and l-glutamine. Sodium benzosulfonate can directly act on the inflammatory mucosa and has an anti-inflammatory effect; glutamine promotes the synthesis of hexylamine and glucosamine, the epithelial component of the gastrointestinal mucosa, and can promote the regeneration of ulcer tissue and enhance the barrier function of the intestinal mucosa.
▌ Directions: Take three times a day, one bag at a time, dissolve with 30ml of warm boiled water and take it.
05
Rebapat tablets
By increasing the content of prostaglandin e2 in the gastric mucosa, increasing the amount of gastric mucus and blood flow, rebapart tablets inhibit the damage of aspirin, ethanol and other gastric mucosa to the gastric mucosa, thereby protecting the gastrointestinal mucosa.
▌Directions: 3 times a day, 1 tablet at a time, orally in the morning, evening and before going to bed.
06
Isola fixes
Isoladine tablets: by increasing the content of gastric mucosal intracellular camps, prostaglandins, reduced glutathione and mucus glycoproteins, strengthen the binding between gastric mucosal epithelial cells, enhance the stability of mucosal cells themselves, and exert mucosal defense.
▌ Directions: 2 tablets (4mg) a day, divided into 1-2 times.
07
Montmorillonite scattered
Montmorillonite scatter has a strong fixative and inhibitory effect on viruses and bacteria in the digestive tract, making it lose its pathogenic effect. In addition, montmorillonite dispersion has a strong ability to cover and protect the montmorillonite dispersal membrane of the digestive tract, which can repair and improve the defense function of the mucosal barrier against the attack factor. It is mainly used for acute and chronic diarrhea.
▌ Directions: Take on an empty stomach, 3 times a day, one bag (3g) dissolved with half a cup of warm boiled water (about 50ml). The first dose is doubled for the treatment of acute diarrhea.
08
Bismuth potassium citrate capsules
Bismuth potassium citrate capsules form a diffuse protective layer covering the ulcer surface in the acidic environment of the stomach, preventing the invasion of gastric acid and enzymes on the ulcer; it has the effect of reducing pepsin activity and promoting the release of prostaglandins in the mucous membrane, thereby protecting the gastric mucosa; it has a killing effect on Helicobacter pylori (hp), thus promoting the healing of gastritis.
▌Directions: Take 4 times a day, the first 3 times half an hour before 3 meals, the fourth capsule 2 hours after dinner, or 2 capsules in the morning and 2 times a day. Note that bismuth potassium citrate should not be taken for a long time, and milk and antacids can interfere with its absorption and cannot be taken at the same time.
09
Gifa ester tablets
Gefa ester tablets are acacia acetate geraniol ester, which can promote ulcer repair and healing, increase gastric mucosal prostaglandins, promote mucus secretion, strengthen the gastric mucosal barrier, expand gastric mucosal microcirculation, and improve blood flow distribution.
▌ Directions: 1-2 tablets three times daily.
10
Ekabet sodium granules
Ekabet sodium granules can form a protective film in the stomach, the coverage of the gastric mucosa is not affected by changes in the pH value in the stomach, and can inhibit pepsin activity, with the effect of inhibiting Helicobacter pylori.
▌Directions: Adults 1 sachet at a time, 2 times a day (after breakfast, before bedtime).
The source of this article is Yixian Pharmacy V and does not represent the views and positions of Chinese pharmacies. If you have any copyright objections to the content and images, please contact us (Email: [email protected]).
Image source: Provided by the brand owner
Dear, The public account of Chinese pharmacies has been open for manuscripts for a long time, such as you want to express your heart, record your life, share your experience... Works can be sent to the [email protected] (mailbox) in the form of text or pictures, and the manuscript fee = 200 yuan + reading amount * 0.01 yuan. As a reminder, please indicate your contact information when submitting
Take a look! ↘