Autumn and Winter
Grapefruit is a favorite fruit of many people
But a woman after eating a grapefruit
Suddenly caused hypotensive shock
What's going on?
Ms. Wang of Changzhou is 60 years old this year, usually has low blood pressure and needs to take medication to control.
In early October, while visiting a fruit shop, she found grapefruits that were freshly on the market and bought two to try. When she went home to eat one, she suddenly appeared dizziness, fatigue and other symptoms, and was immediately sent to the hospital by her family, after examination, Ms. Wang's dilation pressure was once as low as 50, and it returned to normal after rescue.
Tang Lidan, a pharmacist at the Clinical Pharmacy Department of Changzhou Second Hospital, introduced that grapefruit, also called grapefruit, is the offspring of a hybrid of sweet orange and grapefruit, and the flesh is red.
"This grapefruit itself has no effect on blood pressure, but it may interact with some drugs, resulting in an increase in the concentration of the drug in the body, an increase in efficacy, resulting in abnormal blood pressure."
It is understood that grapefruit contains furan coumarin compounds, which will slow down the metabolism of some drugs and prolong the time of action.
nutshell
I ate grapefruit at the same time as I took antihypertensive drugs
This is equivalent to increasing the dose of the drug
Doctors suggest that when taking medicine, it is best not to eat grapefruit, because many drugs will be affected by "furan coumarin". Doctors recommend that patients taking the drug should preferably consume grapefruit after 72 hours of taking the drug.
note! These medications cannot be taken with grapefruit
Antihypertensive drugs (e.g., nifedipine)
In addition to yuzu containing furan coumarin, which can inhibit the metabolism of antihypertensive drugs and increase their blood concentration, yuzu also contains potassium, which is a natural antihypertensive drug. If you take antihypertensive drugs while eating grapefruit, it is like overdosing the drug, causing a sudden drop in blood pressure, light dizziness, nausea, palpitation, and heavy cases of occasional angina, myocardial infarction or stroke.
Anxiolytic or sedatives
Some anxiolytic drugs such as diazepam and midazolam cannot be taken with grapefruit, because grapefruit will prolong the action time of such sedative hypnotics, causing dizziness and drowsiness.
Antiallergics (eg, cismine, terfenadine)
For example, cistimil, terfenadine, etc. can not be taken with grapefruit, because the consumption of grapefruit after taking such drugs will aggravate the adverse reactions of anti-allergic drugs to the heart, liver and gastrointestinal tract.
Anti-rejection drugs (eg, cyclosporine)
For example, cyclosporine cannot be taken with grapefruit, because the blood concentration increases, adverse reactions increase, and increase liver and kidney toxicity. If such drugs are eaten with grapefruit for a long time, there is a risk of tumor induction.
Statins (eg, atorvastatin)
If statins are taken with grapefruit, they will rapidly increase the concentration of statins in the blood in a short period of time, greatly increasing the accumulation of drugs and toxic side effects, and the most obvious side effects of statins are caused by rhabdomyolysis.
Finally delivered
There are common contraindications to taking the drug
↓↓↓
The contraindications between drugs and foods go far beyond the above
So before we take the medication
Be sure to read the instructions carefully
Or consult a doctor or pharmacist
Find out the requirements and contraindications of medication
In order to improve the safety of medication
Do not use drugs blindly