<h1>Patients often ask me, when should this stomach medicine be better to eat, is it before meals? Or do you eat it after a meal? Presumably many people have this question, so today we will talk about the time of various stomach medicines. </h1>
At present, gastric drugs are divided into acid suppression, antacid resistance, gastric mucosal protection, gastric motility, etc. according to the different effects of these drugs, the best time to take drugs is also different, the following I will separately say the characteristics of various drugs and the best time to take drugs.
First, proton pump inhibitors (taken half an hour before meals on an empty stomach)
Let's first talk about the kind of drugs we most often use and the most well-known pazole drugs, that is, we often say omeprazole, lansoprazole, rabeprazole, pantoprazole, esomeprazole and other drugs, such drugs in the scientific name is proton pump inhibitors, such drugs are the last step in the formation of gastric acid, inhibiting the synthesis of gastric acid, and the effect time is longer, so now it has gradually replaced the H2 receptor antagonist in the clinic. It has become the most effective drug for the treatment of various stomach acid-related diseases. This type of drug is recommended to be taken on an empty stomach 30 minutes before meals, so that the drug concentration can reach a peak in the parietal cell secretion tubule for optimal treatment.
Tip: Taking a pazole (proton pump inhibitor) drug in the morning is more effective, because compared to the evening, the bioavailability of taking it in the morning is high, and it can basically act for 24 hours, that is, a day to inhibit the effect of stomach acid. If the dose is larger, it is recommended to take it twice a day, the effect is better.
Second, H2 receptor antagonists (taken at breakfast and dinner and before bedtime)
H2 receptor antagonists are what I usually say about titin drugs, such as famotidine, cimetidine, ranitidine, etc., which can partially inhibit pentapeptide gastrin, histamine and gastric acid secretion caused by food stimulation, and play a therapeutic effect on gastric acid diseases. This type of drug is recommended to be taken at the same time as eating, because the amount of gastric acid secretion after eating will be greatly increased, so it is best to take it at this time. Taking H2 receptor antagonists before going to bed has a good effect, because stomach acid secretes a long cycle at night, so taking it before bedtime can be a good way to inhibit gastric acid secretion, prevent excessive gastric acid secretion at night from causing damage to the stomach, and also avoid the symptoms of acid reflux, heartburn and other gastroesophageal reflux caused by excessive stomach acid.
Tip: Titin drugs (H2 receptor antagonists) are gradually replaced by prazole drugs (proton pump inhibitors) because they are easily tolerated and will have rebound symptoms after stopping the drug, that is, a large amount of gastric acid secretion after stopping the drug.
Third, antacid drugs (take one hour after meals)
Such drugs are often said to be a variety of weak alkaline inorganic salt drugs, such as aluminum hydroxide, and aluminum hydrocarbon magnesium, etc., they through their own weak alkaline characteristics, neutralize gastric acid, inhibit part of the pepsin activity to protect the gastric mucosal wound and achieve drug effect. Such drugs are generally only a small amount absorbed by the intestine, most of them will be excreted with feces, so the length of the effect of this type of drug and the individual gastrointestinal motility and emptying speed is related, the effect of fasting use is only twenty or thirty minutes, taken an hour after eating, the effect can be greatly extended to 2-3 hours, so we should take it after meals, that is, when gastric acid secretion reaches its peak, to achieve maximum efficacy.
Tip: If the effect of this type of drug is not obvious after taking the drug, you can take the same dose of the drug again, because the effect of the drug is sometimes not obvious enough due to the continuous secretion of stomach acid.
Fourth, gastric mucosal protective drugs (this medicine should be taken half an hour before meals)
This kind of drug is what we often call sucralfate, citric acid secret potassium and other drugs, their principle is to form a protective layer on the gastric mucosa, as if adding a layer of armor to the outside of the gastric mucosa, forming a barrier, thereby preventing digestive enzymes and stomach acid from harming the stomach wall and ulcer surface. In order to avoid food blocking the combination of the drug and the stomach wall during or after eating, it is best to take it half an hour before meals.
Tips: Some people ask if eating a few tablets of this kind of medicine before drinking alcohol can not hurt the stomach, we need to know that although this type of drug can form a barrier to protect the gastric mucosa, can reduce the damage to the gastric mucosa to a certain extent, but can not prevent the absorption of alcohol, reduce the liver, kidney and pancreas and other organs caused damage. So it is not recommended to drink alcohol, especially if you have stomach problems.
Fifth, to promote gastric motility drugs (this drug is recommended to be taken 15-30 minutes before meals)
This type of drug is what we are familiar with as bili drugs such as mosabili and cisapride, as well as morphine (domperidone), gastric regasu (metoclopramide) and other drugs, which are drugs that promote gastric motility. Their role is to enhance and coordinate gastrointestinal peristalsis to speed up gastric emptying, improve symptoms such as acid reflux, nausea, vomiting, belching and bloating. Therefore, we recommend taking it 15-30 minutes before meals, so that the concentration of the drug in the blood reaches a peak when eating, so as to obtain the best effect.
Tip: Because this type has the opposite effect on the stomach with anticholine drugs such as atropine, 6542 (scopolamine), etc., the two cannot be used at the same time.
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