All provinces, autonomous regions, and municipalities directly under the Central Government(agriculture and animal husbandry), animal husbandry and veterinary departments (bureaus, committees), and agricultural and rural bureaus of the Xinjiang Production and Construction Corps:
In order to effectively strengthen the comprehensive treatment of veterinary antibacterial drugs, effectively curb the resistance of animal-derived bacteria, rectify veterinary drug residues exceeding the standard, comprehensively improve the level of green and healthy breeding of livestock and poultry, promote the high-quality development of animal husbandry, and effectively maintain the safety of animal husbandry production, food safety of animal origin, public health safety and biosecurity, our ministry has formulated the "National Action Plan for the Reduction of the Use of Veterinary Antibacterial Drugs (2021-2025)", which is hereby issued to you, please organize and implement it in combination with reality to ensure that all work objectives and tasks are completed on schedule.
Ministry of Agriculture and Rural Affairs
October 21, 2021
National Action Plan for Reducing the Use of Veterinary Antimicrobials
(2021-2025)
In accordance with the provisions of the Biosecurity Law of the People's Republic of China, the Law of the People's Republic of China on the Promotion of Rural Revitalization, the Regulations on the Administration of Veterinary Drugs, the Opinions of the General Office of the State Council on Promoting the High-quality Development of Animal Husbandry, and the Three-Year Action Plan for The Treatment of Prohibited Drug Residues in Edible Agricultural Products, and other documents, this action plan is formulated on the basis of the pilot work of the national action on the reduction of the use of veterinary antibacterial drugs.
1. Operational objectives
Focusing on livestock and poultry breeds such as pigs, layer chickens, broiler chickens, meat ducks, dairy cows, beef cattle, and meat sheep, steadily promote the action of reducing the use of veterinary antibacterial drugs (hereinafter referred to as "antimicrobial reduction"), effectively improve the safety, standardization and scientific use of veterinary antibacterial drugs in livestock and poultry breeding links, and ensure that the use of veterinary antibacterial drugs per ton of animal products produced nationwide during the "Fourteenth Five-Year Plan" period maintains a downward trend, and the pass rate of veterinary drug residue supervision and sampling of livestock and poultry products such as meat, eggs and milk remains stable at more than 98%. The trend of bacterial resistance of animal origin has been effectively curbed.
By the end of 2025, more than 50% of large-scale farms will implement breeding and anti-resistance actions, establish and strictly implement the management system for the safe use of veterinary drugs, standardize scientific drug use, and fully implement the veterinary prescription drug system, the veterinary drug suspension period system and the "veterinary drug standardized use" commitment system.
2. Operational tasks
(1) Strengthen the supervision of the whole chain of veterinary antibacterial drugs
1. Strengthen the supervision of the production and operation of veterinary antibacterial drugs. Strictly implement the "Good Manufacturing Practice for Veterinary Drugs (Revised in 2020)", and strictly prohibit veterinary drug production and trading enterprises from producing and selling growth-promoting antibacterial drug feed additives. Increase the intensity of quality supervision and sampling of veterinary antibacterial drugs, implement "inspection and combat linkage", and strictly investigate the implicit addition of prohibited ingredients or other ingredients. Strictly implement the two-dimensional code traceability system for veterinary drugs, ensure that all veterinary drug products are assigned to the market, and all the traceability data of veterinary drug production and operation enterprises' products into the warehouse and out of the warehouse are accurately uploaded to the national veterinary drug product traceability system. Strengthen the management of APIs to prevent illegal inflow into aquaculture. Strengthen the supervision of veterinary drug online sales platforms, and work with industry and information technology departments to severely crack down on illegal sales of fake and inferior veterinary drugs through the Internet.
2. Strengthen the supervision of the use of veterinary antibacterial drugs. Strengthen the supervision of feed production and operation enterprises, improve the detection method standards for illegally added veterinary drug ingredients in feed, organize special monitoring of illegally added drugs and prohibited substances, and seriously investigate and deal with violations of laws and regulations. Strengthen the supervision of drug use in farms (households), except for anticoccumbs and traditional Chinese medicine drugs used in commercial feed, it is strictly forbidden to add any other veterinary drugs to self-ingredients. Compact farms (households) standardize the main responsibility for drug use, supervise and guide farms (households) to establish and improve management systems for the procurement, storage, and use of veterinary drugs, strictly implement the regulations on safe use such as the veterinary drug use record system, the veterinary prescription drug system, and the veterinary drug drug suspension period system, accurately and truthfully record the use of veterinary drugs, and strictly prohibit over-range and over-dose medication. Innovate the management system for the use of veterinary drugs, establish and implement the commitment system of "standardized use of veterinary drugs" in farms (households), and take it as an important basis for independently issuing certificates of conformity for edible agricultural products. When selling livestock and poultry and their products in farms (households), the relevant departments shall check and check the breeding files such as drug use records in accordance with the provisions of the quarantine regulations of the animal origin. Increase the intensity of punishment, give heavier punishments to illegal drug use in accordance with law, and where a crime is suspected, transfer it to the public security department for filing and investigation.
(2) Strengthen risk control of veterinary antibacterial drug use
3. Monitor the amount of veterinary antibacterial drugs used. Make full use of the national veterinary drug product traceability system, monitor and analyze the type, quantity, flow direction of veterinary antibacterial drugs, analyze the changing trend, and timely propose targeted preventive measures.
4. Implement monitoring of veterinary drug residues in livestock and poultry products. Combined with the actual production situation in the jurisdiction, formulate and implement the annual veterinary drug residue monitoring plan for livestock and poultry products, increase the intensity of testing, timely grasp the risk factors, and control the residual risk.
5. Carry out monitoring of drug resistance of bacteria of animal origin. Establish and improve laboratories for monitoring the resistance of bacteria of animal origin, and improve the monitoring system of drug resistance of bacteria of animal origin. Formulate and implement an annual monitoring plan for drug resistance of bacteria of animal origin, organize drug resistance monitoring, and improve the ability to control drug resistance risks.
(3) Support the application of veterinary antibacterial drug substitution products
6. Promote the healthy development of the veterinary Chinese medicine industry. Innovate and improve the access policy of veterinary Chinese medicine, and establish a registration system that conforms to the characteristics of veterinary Chinese medicine and the actual development of the industry. Support the "secondary development" of traditional veterinary Chinese medicines with exact efficacy, and simplify the registration and approval of compound preparations derived from classic recipes. Veterinary Traditional Chinese medicine production enterprises will be included in the scope of support of leading enterprises in agricultural industrialization, and enjoy relevant support policies for agricultural product processing.
7. Selection and promotion of alternative products. Organize relevant teaching and scientific research units, farms (households) that meet the standards of reducing resistance, etc., carry out the screening and evaluation of safe, efficient and low-residue veterinary antibacterial alternative products, and guide farms (households) to correctly select alternative products. Support the promotion of green breeding technology and product research and development, encourage all localities to coordinate grass-roots animal epidemic prevention subsidy funds and other related project funds, and give rewards to farms (households) with great strength and good results in promoting the use of alternative products such as veterinary traditional Chinese medicine.
(4) Strengthen technical guidance services for the reduction of the use of veterinary antibacterial drugs
8. Strengthen publicity and education for practitioners. Strengthen the training and education of breeding subjects and animal husbandry and veterinary technical service personnel, incorporate the relevant technical specifications for the reduction and use of veterinary antibacterial drugs into the curriculum system of high-quality farmer cultivation projects, and make it an important part of the training of rural veterinarians and grass-roots animal epidemic prevention teams. Make full use of various media to popularize the knowledge of standardized drug use, the principle of rotation of drug use, and the method of precise drug use, etc., to improve the awareness and level of standardized drug use by practitioners.
9. Carry out technical services. Implement the "scientific use of veterinary antibacterial drugs" public welfare relay action, give play to the role of the China Veterinary Drug Association, the China Animal Husbandry Association and relevant local industry organizations, organize and guide veterinary drug production and operation enterprises and breeding leading enterprises, invite experts to enter villages and households for on-site technical guidance in the way that companies lead farmers, promote and popularize scientific drug knowledge and technology door by door, and strive to achieve full coverage of technical guidance services for large-scale farms at the end of the "Fourteenth Five-Year Plan".
(5) Construct an incentive mechanism for reducing the use of veterinary antibacterial drugs
10. Carry out evaluation of the effectiveness of anti-resistance reduction in farms (households). On the basis of the evaluation standards of the pilot anti-resistance reduction pilot of our Ministry, all localities have established and improved the evaluation index system for local breeding to reduce resistance, organized the evaluation of the effectiveness of anti-resistance reduction, issued a list of farms (households) that meet the standards, and used it as an important reference for the creation of national-level livestock and poultry standardization demonstration farms. Encourage the antimicrobial farms (households) at or above the provincial level to use the "veterinary antibacterial drug use reduction and standard farm" logo determined by our ministry (separately issued).
11. Promote the typical model of breeding and reducing resistance. Timely summarize and refine the experience and practices of different livestock and poultry breeds to reduce resistance, select a number of typical cases of resistance reduction in farms (households), publicize and promote in a variety of ways, and give full play to the role of demonstration and leadership.
12. Carry out the selection of advanced counties for breeding and resistance reduction. Encourage qualified localities to carry out resistance reduction work in whole counties and townships (towns) in accordance with the requirements of this plan, and give appropriate rewards to places or farms that have better promotion work and higher quality of completion. The Ministry of Agriculture and Rural Affairs will give commendations to counties (cities, districts) that have carried out effective work and have a prominent effect of breeding and resistance reduction, and publish publicity in the media. The reduction of the use of veterinary antibacterial drugs will be included in the evaluation and assessment of food safety work under the State Council, and will be regarded as an important indicator created by the national agricultural product quality and safety county.
3. Implementation requirements
(1) Work deployment. Nationwide implementation will begin in November 2021. Each province combines local realities to formulate an implementation plan for the reduction of resistance actions in its jurisdiction, so as to achieve hierarchical classification, from easy to difficult, orderly arrangement, and report the implementation plan to the Animal Husbandry and Veterinary Bureau of our Ministry by the end of 2021. Each county (city, district) formulates a specific work plan, establishes a ledger with large-scale farms as a unit, and clarifies the specific responsible persons and contacts.
(2) Organize implementation. All provinces should orderly promote the work of reducing resistance in accordance with the implementation plan of the anti-resistance reduction action in their jurisdiction, establish a work dispatch system, strengthen supervision and inspection, discover problems, promote solutions in a timely manner, and report the progress of the implementation of livestock and poultry breeding to the Animal Husbandry and Veterinary Bureau of our Ministry before the end of November each year.
(3) Do a good job of implementation. According to the actual situation of breeding in this jurisdiction, with reference to the "Guiding Principles for the Reduction of the Use of Veterinary Antibacterial Drugs" (Annex), guide and promote the implementation of breeding resistance reduction in farms (households), and clarify the target tasks of antibody reduction. All localities can also organize and implement action measures with higher standards and richer content according to the actual situation, and promote the realization of the goal of global anti-resistance reduction. Adhere to the problem-oriented, concentrate on organizing a series of rectification activities such as the withdrawal of feed additives for growth-promoting antibacterial drugs and the traceability of two-dimensional codes for veterinary drugs, promote the solution of prominent problems, severely crack down on relevant violations of laws and regulations, and form a strong deterrent.
4. Safeguard Measures
(1) Strengthen organizational leadership. All localities should attach great importance to it, earnestly strengthen organizational leadership, put the development of anti-resistance reduction actions in an important position, set up a leading group for the implementation of anti-resistance actions, strengthen organizational coordination and technical guidance, and pool resources, integrate technologies, and gather forces to comprehensively promote the implementation of various policies and measures.
(2) Strengthen policy support. In accordance with the "National Animal and Plant Protection Capacity Improvement Project Construction Plan (2017-2025)", our ministry will actively support the construction of projects related to the monitoring of veterinary drug residues and animal-derived bacteria resistance. All localities should actively strive for the support of development and reform, finance, science and technology and other departments, increase support for key tasks related to the anti-resistance action, and ensure that all measures are effective. Where conditions permit, promote the establishment and implementation of subsidy systems for veterinary antibacterial products such as veterinary traditional Chinese medicine. In terms of application for agriculture-related projects, policy preferences are given to farms (households) that meet the resistance reduction standards.
(3) Strengthen technical support. Give full play to the technical advantages of the National Expert Committee on the Control of Veterinary Drug Residues and Drug Resistance and relevant teaching and scientific research units, provide professional guidance for livestock and poultry breeding to reduce resistance, undertake the task of risk assessment of veterinary antibacterial drug resistance, and provide risk management and policy recommendations. Strengthen the research and development of antibacterial drug substitution, the study of the mechanism of bacterial drug resistance, and the research of drug resistance detection methods and standards. Support the establishment of expert guidance groups for the reduction of the use of veterinary antibacterial drugs in various localities, focusing on technical consultation, on-site guidance, monitoring and tracking, evaluation and demonstration, and other work.
Guidelines for the use of reduction in veterinary antimicrobials
Farms (households) should establish the concept of healthy breeding, prevention first, and comprehensive management according to the epidemic characteristics of animal diseases in the livestock and poultry breeding links and the actual needs of prevention, diagnosis and treatment, and establish and improve the management system, take effective control measures, vigorously grasp the implementation of the implementation from the five aspects of "raising, prevention, regulation, caution and substitution", improve the level of breeding management and biosecurity protection, and promote the realization of the goal of reducing the resistance of the farm (household) breeding.
The first is "raising", that is, accurately managing good breeding "three passes". Put a good breeding mode off, clarify the feeding methods of different livestock and poultry breeds, and finely manage the breeding environment conditions; put a good breed source off, and if there is a condition, we should select excellent breeds and brand manufacturers of livestock and poultry, and strictly check and test the health status of seedlings according to batches to prevent the carrying of vertically transmitted pathogenic microorganisms; we should pass the good nutrition pass, according to the nutritional needs of livestock and poultry at different stages, formulate scientific and reasonable feed formulas, ensure adequate and balanced nutrition, and achieve the purpose of improving the individual resistance of livestock and poultry and the level of group health.
The second is "prevention", that is, comprehensive prevention of the risk of spread of animal diseases. Implement the main responsibility for animal epidemic prevention, firmly establish the concept of biosecurity, focus on improving animal epidemic prevention conditions such as physical isolation and disinfection facilities in breeding sites, strictly implement biosecurity protection systems and measures, actively implement disease immunization and elimination of sources as planned, and reduce the impact of viral, bacterial and other animal diseases from the source.
The third is the "regulation", that is, strictly regulate the use of veterinary antibacterial drugs. Strictly implement the provisions on the safe use of veterinary drugs, strictly prohibit the use of prohibited drugs and other compounds, stop using veterinary drugs, human drugs, and fake and inferior veterinary drugs; strictly implement the veterinary prescription drugs, drug suspension period and other systems, in accordance with the veterinary drug label instructions, symptomatic treatment, correct usage, accurate dosage, to achieve "good use of drugs".
The fourth is "caution", that is, the scientific and prudent use of veterinary antibacterial drugs. Attach great importance to the problem of bacterial resistance, clearly grasp the category of veterinary antibacterial drugs, adhere to the principle of prudent use of drugs, graded classification of drugs, according to the practice of veterinary treatment opinions, drug susceptibility test test results, etc., accurately select veterinary antibacterial products with strong sensitivity and good effect; cautious combination of antibacterial drugs, can be treated with an antibacterial drug and never use multiple antibacterial drugs at the same time; classification and grading selection of drug varieties, can be treated with general level antibacterial drugs never use higher grade antibacterial drugs, can use narrow-spectrum antibacterial drugs without broad-spectrum antibacterial drugs Increase the precise treatment of individual animals, reduce the use of preventive treatment drugs for animal groups, and achieve "less medication".
The fifth is "substitution", that is, the active application of veterinary antibacterial drugs to replace products. Veterinary drug species with high efficiency, short drug suspension period and low residue should be gradually replaced with veterinary drug species with low efficiency, long drug suspension period and easy residue. According to the actual situation of breeding management and epidemic prevention, promote the application of veterinary traditional Chinese medicine, micro-ecological preparations and other residue-free green veterinary drugs, replace some veterinary antibacterial drug species, and gradually increase the proportion of use to achieve ecological green livestock and poultry products.
Source: Bureau of Animal Husbandry and Veterinary Medicine, Ministry of Agriculture and Rural Affairs
Edit: Cheng Ming