Editor's Note In its more than 300 prescriptions, "Treatise on Typhoid Fever and Miscellaneous Diseases" uses 7 formulas such as earth turtle insects, leeches, grasshoppers, grubs, grubs, spiders, bees, rat women, white fish, 9 flavor insects, scattered in the 7 formulas of earth turtle insects, such as soil turtle insects, water lees, spider powder, earth melon root powder, etc., mainly for the treatment of blood accumulation evidence, blood stasis and internal amenorrhea, abdominal pain, hisnia, malaria mother, cold condensation of the liver vein of the yin fox hernia, etc., in order to achieve blood stasis, blood circulation, pain relief, anti-accumulation of hernia, ulceration, etc., in order to achieve blood stasis, blood circulation through pain relief, elimination of ulcers, ulceration and other multiple treatment purposes. It shows the unique efficacy and application of insect drugs. From now on, this edition will publish the sexual taste and efficacy of these 9 flavor insect drugs in the "Treatise on Typhoid Fever and Miscellaneous Diseases" and its modern research.
Earth turtle worms
It is the dried body of the female turtle or jidi turtle insect of the turtle family, also known as insect and soil element. The medicinal properties are salty and cold, there is a small poison, and it belongs to the liver meridian. It has the effect of breaking blood and stasis, continuing tendons and bones, treating bruises, tendon fractures, bruise pain and blood stasis menstrual amenorrhea, postpartum stasis abdominal pain, accumulation of lumps, etc.
Zhongjing uses this product in a total of 4 parties, namely the turtle shell decoction pills for the treatment of "fistula" and "malaria mother", there is dry blood in the treatment, skin nail error, two eyes dark rhubarb worm pills, the treatment of postpartum abdominal pain of the lower stasis blood soup and the treatment of menstrual water is unfavorable, less abdominal pain of the potato root scatter. Its function, "Changsha Medicinal Solution" yun its "elimination of tuberculosis and breaking the stasis also", "Materia Medica Tongxuan" said that it "broke all blood accumulation", "Medicinal Properties" said that it "broke the accumulation of blood", "Materia Medica" said that it "postpartum blood accumulation, broken bruises and bruises". The "Materia Medica" is further elaborated, saying: "Salty and cold into the blood soft and firm, so the Lord's heart and abdomen blood accumulation, fistula blood closed evidence ... He also treats malaria as a necessary medicine. ”
Combining the above, it is enough to prove that the earth turtle can move its stasis, remove its closure, for the blood to break the menstrual passage, attack the stasis and eliminate the epilepsy of the product, modern clinical often use alone or with compound treatment of tendon fractures, acute lumbar sprains, sciatica and coronary heart disease, hypertension, advanced tumors, etc.
Studies have shown that the main body of the earth turtle contains 17 kinds of amino acids such as glutamic acid and arsenic and other trace elements, and its extract and hydrochloride sediment have anti-thrombosis and thrombolytic effects, respectively; the extract can inhibit platelet aggregation, reduce adhesion rate and aggregation number, etc.
leech
Leeches are the dried bodies of leeches, leeches and willow-leaved leeches in the leech family, commonly known as ants and horse turtles. The medicinal properties are salty, bitter and flat, and there is a small poison, which belongs to the liver meridian. It has the effect of breaking blood through menstruation, eliminating stasis by stasis, and is mainly used to treat blood stasis and menstrual closure, accumulation of fistula, bruises, abdominal pain, etc.
Zhongjing leeches are found in Rhubarb Worm Pills, Dangdang Tang, and Dangdang Pills. The "Materia Medica" says that it is "a medicine for chasing away evil blood and stasis"; the "Medical Heart of Zhongshen Xilu" says that it "ranks first in the blood-breaking medicine"; the "Materia Medica" says that it "Zhongjing Fang into the rhubarb worm pill to cure dry blood, bone steaming, skin nail errors, cough into labor... Entering into the soup and pills to cure typhoid fever has a hard lower abdomen, urinates self-interest, and is crazy and belongs to the blood store." Zhongjing water leeches are used with leeches, peach kernels, and rhubarb, such as the "Materia Medica" cloud "(leeches) its function is similar to that of leeches, so Zhongjing Fangzhong often runs parallel to it"; "Daixueyuan Ancient Fang Annotated" explains that "leeches can lead peach kernels to attack blood, rhubarb is hot, and break the ruthless blood knot". It can be seen that Zhongjing uses leeches to take the work of breaking blood and chasing away stasis.
Modern clinics often use or combine to treat coronary heart disease, angina, hyperlipidemia, hypertension, cirrhosis, kidney disease and polycythemia vera, especially in the prevention and treatment of cardiovascular and cerebrovascular diseases and anti-cancer.
Studies have shown that leeches mainly contain protein, and saliva contains hirudin, heparin, antithromboxane and histamine-like substances. Its decoction has a strong anticoagulant effect, which can significantly prolong the agglomeration time of fibrin, has a significant inhibitory effect on platelet aggregation, inhibits thrombosis in rats, and has a good therapeutic effect on diffuse intravascular coagulation. In addition, leech decoction has obvious protective effect on renal ischemia, can reduce serum urea nitrogen, creatinine level, and has a significant reducing effect on elevated serum tumor necrosis factor.
Fly
Flies are female insects of the family Flies, also known as cattle flies. The medicinal properties are bitter and cold, and there is a slight poison. Return to the liver meridian. It has the effect of breaking blood and stasis, dispersing accumulation and eliminating ringworm, and is mainly used to treat blood stasis and menstrual amenorrhea, accumulation of fistula and bruises, stasis, swelling and pain.
Zhongjing uses flies in three directions, namely, the treatment of scorched blood storage certificate of the Dangdang soup, the Dangdang pill, the treatment of hypothesia with blood stasis of the rhubarb worm pill. The "Benjing" states that it "staches blood, breaks the blood accumulation, the stenosis, the cold and heat, the tongli blood veins, and the nine tricks"; the Benjing Shuzhi says that it is "the agent of searching... The "Beilu" says that "the main woman's moon water is not clear, accumulates, and removes the blood of thieves in the chest and abdomen and the five organs, and the throat is congested"; the "Rihuazi Materia Medica" contains its "elimination of pus, abortion"; "Materia Medica" yun its "flies, its use is roughly similar to that of insects, and this is bitter, bitter can release knots, sexual goodness to eat cattle, horses and blood, the taste should be salty, salty can walk blood, so the Lord accumulates all blood knots into diseases." It can be seen that Zhongjing uses fly insects in the square to go straight into the meridians, breaking the blood and stasis.
Modern clinics are commonly used to treat coronary heart disease, angina, etc. Studies have shown that flies water extracts have a weak antithrombin effect in vitro, in vitro and in vivo have the effect of activating fibrinolytic system, can significantly prolong bleeding time, reduce plasma fibrinogen content, significantly inhibit platelet aggregation rate, reduce whole blood viscosity ratio and plasma viscosity ratio, reduce red blood cell hematocrit, improve blood rheology.
dung beetle
Dung beetles are dried whole insects of the insect dung beetle of the family Scarab, also known as shell lang. Medicinal salty and cold, toxic. Return to the stomach, liver, and large intestine. It has the effect of breaking blood and stasis, attacking poison and laxative, extinguishing the wind and fixing the alarm, and is commonly used to treat epileptic mania, constipation, gonorrhea, cancer, hepatosplenomegaly and prostatic hyperplasia.
Zhongjing uses dung beetles only to see the side of the turtle shell decoction pill for the treatment of fistula. The use of dung beetles in Fangzhong, such as the "Changsha Medicinal Solution", said: "Dung beetles are good at breaking fistulas, can open dry knots, and use them in the "Golden Cockroach" turtle shell frying pills to cure malaria for a long time, and open knots with its broken fistulas." "Explain that Zhongjing uses dung beetles, takes its effect of breaking blood and stasis, and eliminating the effect of spreading knots." Modern clinical treatment of bladder stones, urethral stones, paralytic intestinal obstruction, etc. Studies have shown that the oleochemical composition of dung beetles contains a large number of unsaturated fatty acids and odd carbon fatty acids that are rare in nature, and contains free amino acids, total amino acids and so on. Its alcohol extract has an inhibitory effect on human liver cancer cells, inhibits the ex vivo heart, rabbit intestinal tube and uterus of toad, has a temporary dilation effect on blood vessels, has a paralyzing effect on neuromuscular specimens of toads, has a significant inhibition of experimental prostatic hyperplasia, and has the effect of anti-α receptor agonist norepinephrine induced bladder deltoid muscle contraction.
spider
Spiders are whole insects of the family Cyprinidae, such as the large-bellied round web spider. Medicinal bitter cold, toxic. Return to the liver meridian. It has the effect of dispelling wind, reducing swelling and detoxification. Commonly used to treat fox hernia partial fall, stroke mouth crooked, children slow alarm, mouth gag, chancre accumulation, boils, fistula, sore carbuncle and so on.
Zhongjing used this product to see only the spider scattering of "yin fox hernia, partial size, up and down all the time", which was caused by cold condensation of the liver meridian. The spider in the square is the king's medicine, breaking the knot and li qi, with the xinwen of the guizhi branch, and introducing the yin and liver meridians to disperse the cold qi, which is combined into the agent of xinwen tongli. The Second Commentary on the Golden Jade Letter Says: "The spider cloth web takes the object, and its silk is wrapped to the right, from the outside to the inside, the wind is not bad, and the righteousness of a thousand gold rotation is obtained, so the demon fox of the wind and wood is the main ruler, and the guizhi branch is used to disperse the yin qi knot." "Because the spider is poisonous and fierce, later generations often match orange core, neem, incense, cumin and other liver-thinning products to make it, the effect is better."
grubs
Grubs are dried larvae of insects of the family Scarabidae, Korean black scarab beetles or other closely related insects, also known as silkworms and earth silkworms. Mildly warm, salty and toxic. It has the effect of breaking blood and stasis, attacking poison and scattering knots, and is commonly used to treat bruises, gout, tetanus, laryngeal paralysis, erysipelas, carbuncle, hemorrhoid fistula and so on.
Zhongjing uses grubs only in the treatment of "dry blood, skin nail errors, dark eyes" of the rhubarb insect pills, Fang Zhong with its salty can walk blood, the medicinal properties are fierce, squirming blood, aimed at moving its stasis, to close it. The Book of Scriptures states that "the Lord's evil blood, the blood stasis and paralysis, the broken blood under the coercion of the strong pain, the moon closed." The Compendium of Materia Medica says: "It can perform blood division and scatter stagnation." "Changsha Medicinal Solution" Cloud: "It can dissolve blood stasis and eliminate the most lumps." "Golden Kuai" rhubarb insect pills are used to cure fatigue and full stomach, with dry blood inside, and to dissolve the accumulation with its broken stasis. The "Benjing Shu Evidence" says that "the stasis medicine used by Zhongjing is no less than one or twenty flavors, and the dry blood of the two eyes is dark to prove the use of grubs", which shows that the grubs have a stronger ability to break the blood and chase the stasis.
Studies have shown that grub water immersion above 1:1000 can excite the rabbit palace in vitro; 1:10000 concentration has a constrictive effect on rabbit coronary blood vessels, in vivo rabbit ear blood vessels, toad lung blood vessels; higher concentrations can also constrict the internal blood vessels of toads.
Dew beehive
The bee wasp is the nest of the hornet insect bumblebee or a close relative insect of the same genus, which is now customarily called "dew hive". Medicinal ganping, toxic. Return to the liver and stomach meridians. It has the effect of dispelling wind, attacking poison and killing insects. It is commonly used to treat epilepsy, wind paralysis, hidden rash itching, cradle carbuncle, hemorrhoids, fistula, wind and fire toothache, tinea head and so on.
Zhongjing uses this product only in the treatment of "fistula mother" of turtle nail pan-fried pills 1 party. This side is used both cold and hot, attacking and supplementing, and is the main party for curing malaria mothers. The use of fangzhong bee is not the main drug, it is intended to attack the poison with poison, take its effect of attacking poison to reduce swelling, and kill insects and scatter knots. The "Materia Medica" is called "dispelling the wind and attacking poison, scattering boils and swelling and viciousness"; "Beilu" says "healing bee venom, poisonous swelling". Modern clinical with Wushan Cigu, whole scorpion, etc., the treatment of a variety of carbuncle sore poison, fistula, especially the treatment of milk carbuncle effect is better. Studies have shown that bee extract has the effect of promoting blood clotting and can enhance heart movement, so that blood pressure drops for a short time.
Rat woman
Ratwort is the dried whole of the rat gynecological animal flat beetle, also known as flat beetle, wet worm. Medicinal acid cool, returned to the liver meridian. It has the effect of breaking blood through menstruation, water through water, detoxification and pain relief. It is commonly used to treat long-term malaria, malaria mother, menstrual amenorrhea, fistula, unfavorable urination, convulsive mouth, mouth pain, thrush and so on.
Zhongjing uses this product only to see 1 side of the turtle nail fried pill for the treatment of "fistula and malaria mother". The purpose of the use of the rat woman in the square is to break the stasis and eliminate the firmness, disperse the knots and dissolve the depression, and match the turtle beetle, zhe worm, and bee bee, and play the role of dissolving the stasis and eliminating the malaria, killing the insects and stopping the malaria. Huang Yuanyu said that "good through the meridians, can eliminate the ringworm disease", "Materia Medica Truth-seeking" said "to dispel cold and heat stasis", "Materia Medica" cloud "cure long malaria cold and heat". Nowadays, it is taken to break the blood stasis, the role of the meridians, and the clinical use of the treatment of fistula accumulation, menstrual amenorrhea and dysmenorrhea blood stasis, often used with peach kernels, safflower and the like.
Whitefish
Whitefish are the dried whole of the insects of the family Yiyu. Also known as cloth fish, silverfish, wall fish, bookworm. The medicinal properties are salty and warm, toxic, and belong to the small intestine, bladder, liver meridian. Diuretic, lymphatic, wind removal, detoxification effect, commonly used to treat gonorrhea, urinary disadvantage, pediatric seizures, boils, eyes and so on.
Whitefish is only found in the "Golden Essentials" talc whitefish scattered 1 side, cloud: "Urinating is not good ... Talc white fish scatter, Poria rong salt soup and the main one. "Talc white fish scattered with talc, hair and other parts as the end, the lord urinating is not good, but to take its beneficial water through the work." The Shennong Materia Medica says "healing drenching" and "theory" says "therapeutic abortion", both of which are said to be able to benefit water and water. At present, it is believed that white fish is known for treating blood, but it is generally less clinically used.
Wu Liming Henan Nanyang Medical College