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Can probiotics really regulate the stomach and intestines?

Today's young people have a fast pace of life and irregular schedules, resulting in many people's stomachs not being very good. No, today a friend said that he recently had a bad stomach, poor digestive function, and was very distressed. Today, I will talk to you about how to deal with bad stomach.

01. Gastroscopy

For people with bad stomach, it is first recommended to do a gastrointestinal endoscopy, because gastrointestinal problems, we must first rule out organic problems, if there is an underlying disease, then directly follow the doctor's treatment opinion for treatment. Don't worry about discomfort, now the painless gastrointestinal endoscopy is very easy, sleep for an hour or so after anesthesia, you get the report, basically no feeling.

If no obvious pathological problems are found, then at least to some extent, it can be reassured. And then there are gastrointestinal problems, then you need to do a good job of daily conditioning.

02, intestinal microbiome

After the organic problems have been eliminated by gastroscopy, we are ready to start conditioning the gastrointestinal tract. How to condition it?

The first thing that needs to be adjusted is diet, such as avoiding irritating foods, eating on time, not overeating, etc., Presumably everyone already knows. I'll talk about another point of concern here: the gut microbiome, also known as the gut microbiome.

Can probiotics really regulate the stomach and intestines?

Many times, we talk about bacterial discoloration, after all, many diseases are caused by microbial infections, however, in our human body, there are very large-scale microorganisms, that is, intestinal microorganisms.

How large are the gut microbes? There are only a few dozen or hundreds of cells in our human body, and there are thousands of types of gut microbes. The number of cells in the human body is only ten trillion, and the number of gut microorganisms in the human body is as high as ten trillion.

It can be said that from a certain point of view, the human body can even be seen as a colony of intestinal flora, so scientists also call the intestinal microbiome the second genome of the human body.

Intestinal microorganisms are not simply gathered in the intestine, but are closely related to the health of the human body, typical of the digestion of the human body.

The intestinal flora is firmly bound in our body, especially the digestive tract, which is of great significance for the absorption of nutrients. For example, it can produce some unique enzymes to promote the digestion and absorption of food, thereby improving the decomposition of organic acids, fats, etc., and for some of our difficult to absorb nutrients, the gut microbiome also plays an important role [1].

In addition, it also includes a series of effects on immunity and health [2].

If the intestinal microbial balance is destroyed, it will lead to gastrointestinal problems in the human body, such as many people going to other places prone to diarrhea, the problem may be caused by the intestinal microbial balance because of the inability to adapt to the place. Because of this, the gut microbiome is critical to the health of the human body, especially digestion.

03, how to regulate the gut microbiome?

An important strategy is to supplement the gut microbes needed by the human body, so what microbes are needed by the human gut? It depends on what are the ingredients in our gut microbiome?

The following figure is a diagram of intestinal microbiome from the Institute of Microbiology of the Chinese Academy of Sciences

Can probiotics really regulate the stomach and intestines?

How about looking familiar? Bifidobacterium? Lactobacillus? In fact, aren't these the probiotics we are familiar with?

Yes, it is true, the probiotics commonly added to the probiotic products on the market are originally the dominant flora in the intestinal flora, and it is precisely because we have studied the gut microbiome and found that they can coexist with humans for a long time, so the researchers isolated these flora and further found that these bacteria are indeed beneficial to humans. With the development of the market and the industry, the application of probiotics in the market is also increasing, such as some of our common yogurt, probiotic preparation products and so on.

04, Is it useful to supplement probiotics?

For supplemental probiotics, the most common problem that plagues many people is: the food we ingest will pass through the strongly acidic stomach, will it cause the probiotics to not reach the intestines at all?

The answer is no.

The most direct evidence is: when the baby is just born, there are no microorganisms in the intestine, and then a large scale of microorganisms is formed. Nature enters from the mouth, so some microorganisms can withstand the test of stomach acid and reach the stomach.

For example, the following is a study after the intake of a strain of Lactobacillus, through the collection of stool from volunteers who took oral Lactobacillus, it was found that after taking Lactobacillus 14 days, the bacteria reached 108.41 CFU/g in the stool. It can be seen that microorganisms can indeed pass through the stomach smoothly without being completely destroyed [3].

Can probiotics really regulate the stomach and intestines?

Not only that, probiotics are not a simple passer-by, they will colonize in the intestine, for example, after 7 days of stopping oral administration of the probiotic, the volunteer feces can still detect 105.52 CFU/g of probiotic activity, which shows that the bacteria have actually completed colonization in the intestine.

From the above evidence, we can see that oral probiotics can not only not be killed by stomach acid, but also reach the stomach smoothly, but also colonize the intestine.

And since they can colonize, it means that they become an integral part of the gut microbiome and start to play a role.

Because of this, for people with a bad gut, you may wish to try supplementing with probiotics.

In fact, there are many products in life that can supplement probiotics, such as yogurt, and there are many other products that can also supplement probiotics.

Of course, daily care for the stomach and intestines is also very necessary, some helpful advice can be tried.

1, regular diet: many people because of work, overtime, play or emotions, eat irregularly, which will greatly affect the stomach and intestines, because of long-term adaptation, our stomach digestion power including gastric juice secretion will form a more regular characteristics, and irregular diet will lead to gastrointestinal problems.

2, avoid drinking alcohol and irritating foods: this is also very important to pay attention to. Although the stomach is very strong, it is still vulnerable to injury, such as drinking, which is not only irritating, but also a class of carcinogens, and other irritating foods should also be moderate.

3, balanced diet: balanced diet is very critical to health, especially vegetables and fruits coarse grains and other foods, not only rich in nutrition, but also to promote gastrointestinal peristalsis, so daily also strive to achieve a balanced diet.

1 Oezbas, Z. Y., and S. A. Aytac. "Behaviour of Yersinia enterocolitica and Aeromonas hydrophila in yogurt made with probiotic bacteria: Bifidobacterium infantis and Lactobacillus acidophilus." Milchwissenschaft (Germany) (1995).

2 Wang Shanshan,Wang Jiakun,Liu Jianxin. Regulation of intestinal microorganisms on the host immune system and its possible mechanisms[J].Acta Zootrophionegica Sinica,2015,27(02):375-382.

3 MA Chen, ZHANG Heping. Probiotics, intestinal flora and human health[J]. Science & Technology Review, 2017, 35(21): 14-25.

4 Leo R. Fitzpatrick,Jeffrey S. Small,Wallace Greene,Kelly Karpa,David Keller. Bacillus Coagulans (Bc 30 ) Improves Some Indices of Clostridium difficile -Induced Colitis in Mice[J]. Gastroenterology,2011,140(5):