Osteoporosis is a relatively harmful orthopedic disease. At the same time, the healing process is also relatively long. But most people are not well aware of the symptoms of the disease. The following is an introduction to several common symptoms of bone marrow hyperplasia for your reference.
infect
Infection occurs due to granulocytopenia and dysfunction, the initial stage of the disease (refractory anemia, RA) is more stable, mostly no serious infection and fever, and the later stage (RAEB or RAEBt) is more likely to be co-infected. Due to low immunity, it is easy to cause potential abscesses and less common infections such as septic arthritis, tuberculosis, Pseudomonas aeruginosa conjunctivitis, and gangrene. Mold infections are more common in later stages, and sepsis is often a comorbidity and the main cause of death at the end of the disease.
anaemia
Except for a few patients, the vast majority of patients have symptoms of anemia of varying degrees as the main clinical manifestations, such as pallor, dizziness and fatigue, palpitations and shortness of breath after activity.
Signs
Some patients may have mild enlargement of the liver, spleen, and lymph nodes, which can occur at the same time or alone, and are easily ignored because the degree is not significant. A small number of patients may have sternal tenderness, rib or extremity joint pain.
haemorrhage
More than half of the patients have bleeding, but the early bleeding symptoms are mild, mostly bleeding from the skin and mucous membranes, bleeding gums or epistaxis, because it is not serious, rarely require special treatment, and female patients rarely have menorrhagia; However, as the disease progresses to an advanced stage, the bleeding trend worsens, and cerebral hemorrhage becomes one of the main causes of death in patients.