Cervical cancer is a malignant tumor associated with HPV, that is, human papillomavirus infection, with high morbidity and mortality, which seriously threatens women's health.
If HPV continues to be infected with cervical cancer, it usually takes a relatively long time, about 10 years. From hyperplasia to dysplasia, to carcinoma in situ, to invasive carcinoma.
A precancerous lesion is defined as a transition from dysplasia to carcinoma in situ. Dysplasia is divided into high-grade dysplasia and low-grade dysplasia. The purpose of cervical cancer screening is to detect precancerous lesions and treat them in time to prevent them from progressing to invasive cancer.
Precancerous lesions of the cervix progress to cervical cancer
How long does it take?
It is mainly classified as precancerous or invasive according to the depth of invasion.
Precancerous lesions of the cervix generally do not invade the basement membrane, and are above the basement membrane, or at most 3 millimeters below the basement membrane, which is called early invasion. Cancer cells that invade the basement membrane less than three millimeters are called invasive carcinoma, and the prognosis is relatively poor. Early invasion, carcinoma in situ, high-grade lesions, and low-grade lesions are all precancerous lesions.
If it is a low-grade lesion and develops to cervical cancer, it generally takes a long time, about half a year to a year. If it is a high-grade lesion, it will develop into invasive cancer within about three months or six months. Of course, this number is not absolute, there is a big difference in different situations, and the general situation is such a time period.
In general, low-grade lesions should be managed, but if fertility is desired, with close follow-up and evaluation by a gynaecologist, fertility may be considered before managing the cervical lesions. For those who do not have the need to have children at present, they should be dealt with in a timely manner. High-grade lesions should generally be treated as soon as possible to prevent the development of invasive cervical cancer.
Resources:
Medical Microvision Official Website - Liu Dongge, Chief Physician "Pathological Diagnosis of Cervical Cancer and Precancerous Lesions"
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