北京时间7月6日凌晨零点，欧洲杯1/4决赛迎来第一场比赛，东道主德国队对阵西班牙队，上半场双方互交白卷。 下半场，奥尔默禁区推射打破场上僵局，维尔茨破门扳平比分，加时赛梅里诺头球绝杀，最终西班牙2-1淘汰德国，
In the first minute of the opening game, Spain formed a goal, Pedri's shot at the top of the arc of the penalty area was confiscated by the goalkeeper, and in less than 6 minutes, Spain had 3 people fall to the ground one after another, and the intensity of the scramble was very large, and in the 7th minute, Pedri retired with tears and was replaced by Olmo. In the 10th minute, Raum quickly cut into the penalty area, swept in front of the goal, and was confiscated by Simon. In the 13th minute, Nico Williams' long-range shot from outside the box went wide, and in the 14th minute, Olmer's breakthrough at the edge of the box was brought down by Rudiger, and the referee gave Spain a free kick and Rudiger a yellow card, and if Germany advances, Rudiger will face a ban.
In the 15th minute, Yamal's free kick was deflected. In the 17th minute, Fabian hit a long-range shot from the top of the penalty area and flew out of the bottom line. In the 21st minute, Kai Havertz's header was confiscated by Simon, and in the 23rd minute, Laporte's shot was held by Manuel Neuer. In the 27th minute, the German team took a free kick into the penalty area, and the ball was picked up by Simon after a scuffle. Raum and Lenormand then received yellow cards in quick succession while defending. In the 34th minute, Havertz attacked down the middle and turned to Emlejan, who passed to Kimmich, who quickly cut in on the right, and Kimmich's cross was confiscated by Simon in front of goal. In the 35th minute, Havertz's shot from the middle of the penalty area was firmly held by Simon, in the 40th minute, Olmo's long-range shot was defused by Neuer, and in the 46th minute, Yamal's long-range shot was firmly held by Neuer when he broke through.
In the second half, in the 48th minute, Morata turned and shot high in the penalty area, and Morata signaled to the referee that the opponent had a foul, but the referee ignored it. In the 52nd minute, Spain launched an attack in the middle, Yamal won the ball on the right side and went to the edge of the penalty area, crossed to Olmo, who quickly inserted, and the latter pushed to break the deadlock on the field, and Spain led 1-0. The German team, which was down by one goal, replaced Gundogan with substitute Phil Kruger. In the 67th minute, Kroos brought down Olmo while defending and received a yellow card. 第70分钟，西蒙扑出了安德里希的远射。 第77分钟，菲尔克鲁格禁区内倒地射门打在立柱上。 第89分钟，维尔茨一脚抽射扳平比分。
In extra time, Spain, who had repeatedly escaped danger, relied on Merino's header to score a goal, and Spain defeated Germany 2-1 to advance to the final.