I heard such an interesting thing from a friend, my friend's friend is a 45-year-old middle-aged man, married a wife who is 13 years younger than himself, in order to ensure the harmony of the life of the two people, the husband will eat some "peanuts" every day, in fact, this peanut is not just a peanut, it also adds tadalafil, every time after eating peanuts, this husband can behave in bed, the little wife is also very satisfied, but one day when the wife cleaned up the room, I felt that the "peanut" time was too long, It may have expired, so I threw the peanuts away for him, and went to the supermarket to buy him new peanuts......
This little oolong incident is ridiculous, and some friends can't help but ask, if you are a person who often takes drugs such as tadalafil, if for some reason, it is stopped all of a sudden, what will be the effect on the body? Are there any health risks? Today, I will combine this issue and talk to you about this topic.
Tadalafil is abruptly discontinued, and there is no need to worry about rebound
Withdrawal rebound refers to a drug phenomenon that will trigger a rebound of the disease if it is abruptly stopped for some reason in the process of taking a certain drug for a long time to alleviate the disease. To illustrate the phenomenon of "withdrawal rebound", friends who have been taking β receptor blocker drugs such as betalux for a long time, especially in the case of a large dose, if the drug is stopped suddenly β, after the regulatory effect of the receptor blocker on the sympathetic nerve and heart rate disappears, it may cause rebound phenomena such as increased blood pressure and tachyarrhythmia, which is a particularly noteworthy medication safety matter; Some friends often reflux acid and will take antacid drugs such as omeprazole for a long time, if such drugs are stopped suddenly, it may also lead to excessive secretion of gastric acid, bringing the problem of rebound after stopping the drug.
But for drugs like tadalafil, such worries are not necessary. Tadalafil is a very commonly used drug in the field of male dysfunction treatment, and its mechanism of action is the same as that of sildenafil and other drugs, which is through the exclusive inhibition of the activity of phosphodiesterase type 5, thereby reducing the degradation of vasoactive substances cGMP, improving vasodilator ability, and improving male function.
What happens if tadalafil is stopped suddenly?
There is more than one possible outcome and answer to this question. Let's share with you a few of the most likely scenarios.
If there is no problem with male function, and the friend who takes tadalafil is just to "improve the state", first of all, it is recommended not to take medicine without relevant indications, in this case, even if the drug is stopped, the male function can still play normally, and there will be no adverse effects.
If you have a friend who has related problems, and often takes tadalafil on demand before the activity, if the drug is stopped, the effect of the drug will no longer exist, and in this case, most patients who stop taking the drug, the problem of male dysfunction will still exist, in this case, if you want to improve the related problems, you should still choose a reasonable dose according to the doctor's advice to continue to take it.
For the friends in the aforementioned story, if you don't want to have the embarrassing situation of taking the drug in advance and being seen by your partner, there is really no need to cover it up with "peanuts", for tadalafil, a long-acting drug, its effect can last up to 36 hours, and you can take the drug during the day on the day of the event, and it is still effective at night, of course, if you are a friend who does not need to consider the above situation, take the medicine 1 to 2 hours before the event, and the drug can also play a better role.
There is also a situation of taladafil is a low-dose regular medication, in this case, it is generally recommended to choose a dose of 5mg and insist on taking it every day, so as to achieve a steady blood concentration, which has a good improvement effect on improving male function, especially the function of couples at other times outside of activities.
In this case, it is also necessary to stop taking the drug after a period of time, such as 1 to 2 months. There may be two conditions after stopping the drug, regular use of tadalafil, in addition to continuous improvement of male function, for the impairment of vascular endothelial function, also has a certain repair effect, therefore, for some patients with mild ED, after stopping tadalafil, male function may also be well maintained, which is also one of the goals of low-dose regular daily tadalafil medication; In addition, for some patients with moderate to severe ED, after regular medication is stopped, they may still be unable to maintain continuous male function, and they still need to take or continue to take the drug as needed.
When do I need to stop tadalafil?
Different from the "passive withdrawal" in the story at the beginning of the article, in some cases, some friends do have a situation where tadalafil should be stopped, and in which cases should the drug be stopped in time? Let's briefly talk about 3 common situations.
The first is the situation that the adverse reaction of taking the drug cannot be tolerated. Taking tadalafil, the possible adverse reactions include headache, dizziness, palpitations, muscle pain, gastrointestinal discomfort, atopic dermatitis caused by allergies and other conditions.
The second situation is that the medication has changed, for example, some patients with coronary heart disease, need to regularly take nitroglycerin, isosorbide mononitrate and other vasodilator drugs, if the original regular use of tadalafil, in this case should also stop the medication, tadalafil and nitrates can coordinate the dilation of blood vessels, bringing a fatal risk of hypotension, between the treatment of heart disease and the improvement of male function, of course, it is better to solve the heart problem first, so it is recommended to stop tadalafil.
The third situation is that the patient's body has changed, and the body is no longer suitable for marital activities, such as acute myocardial infarction, during the recovery period after stroke, unstable coronary heart disease patients, and some other conditions that are not suitable for activities, should also stop taking drugs in time to take care of their body.