In recent years, TCM extracts have attracted much attention in the pharmaceutical community, especially those that can be extracted from TCM as a single ingredient, which are ideal for anti-cancer drugs due to their clear effects and lower side effects. Among them, ginsenosides, as a typical representative of this field, have found anti-cancer active ingredients in ginseng, American ginseng, and Panax notoginseng (Panax Panax family), and show rich anti-cancer effects. At present, ginsenosides have been widely used in the adjuvant treatment of cancer.
Ovarian cancer, as one of the most difficult types of female tumors, often has inconspicuous early symptoms, resulting in many patients being diagnosed in the middle and advanced stages, which is extremely difficult to treat. In addition, the risk of recurrence of ovarian cancer after surgery is also quite high, which poses a great challenge for doctors and patients.
Many ovarian cancer patients are concerned with one question: Is ginsenosides helpful in ovarian cancer treatment? Can it be of substantial help to patients? Recently, a study gave a clear answer.
The research team from Zhongshan Hospital affiliated to Fudan University found that ginsenoside Rh3 has a significant inhibitory effect on ovarian cancer cells through in vitro cell experiments. This discovery opens up new possibilities for the treatment of ovarian cancer and demonstrates the great potential of ginsenosides in the field of anti-cancer.
In the experiment, the researchers divided the human ovarian cancer cells into two groups, one was the experimental group, with 100 μm/ml of ginsenoside Rh3 added, and the other was the control group, with the same amount of culture medium added.
The study found that with the prolongation of ginsenoside Rh3 action time, the survival number of ovarian cancer cells in the experimental group was significantly less than that in the control group, and after 12 hours, the drug effect entered a plateau, and the time continued to be extended, and the survival number of ovarian cancer cells in the experimental group was no longer significantly reduced.
This results indicate that ginsenoside Rh3 can significantly inhibit the growth and proliferation of ovarian cancer cells, and the action time can reach 12 hours.
So how does ginsenoside Rh3 inhibit the growth and proliferation of ovarian cancer cells?
Ginsenoside Rh3, which induces apoptosis in ovarian cancer cells
In the experiment, the researchers found that ginsenoside Rh3 inhibits the growth and proliferation of ovarian cancer cells and kills ovarian cancer cells by inducing apoptosis of cancer cells through orthotopic end staining.
Ginsenoside Rh3 initiates the intrinsic pathway of apoptosis by altering the permeability of the mitochondrial membrane of ovarian cancer cells, which leads to ovarian cancer cell death.
The study proved that ginsenoside Rh3 can significantly inhibit the growth and proliferation of ovarian cancer cells, which is a potential drug for the treatment of ovarian cancer.
W+NMN breaks through the traditional boundaries and incorporates rare ginsenosides from the primeval forests of Tongas into its excellent formula. This precious ingredient is not comparable to ordinary ginseng, but is a treasure given by nature. We have carefully selected 20 kinds of rare ginsenosides, combined with precious ingredients such as ginsenosides, Ganoderma lucidum broken wall, bird's nest peptides, wolfberry, etc., through 10 times natural concentrated extraction technology, to ensure the extraordinary quality and unique effect of the product.
In the manufacturing process, we use cutting-edge Bonzyme biocatalytic enzyme technology to efficiently convert ginsenoside precursors into Rh2/Rg3, and accurately synthesize two isomers, S and R, with a content of up to 98%, thus greatly improving their activity and enabling them to play a precise targeting role.
RH2 has shown remarkable effects in inhibiting the metastasis of malignant cells, enhancing immunity, and promoting postoperative wound healing and physical recovery, making it an ideal choice for postoperative recovery. Rg3 plays an important role in inhibiting the production of tumor cells, whether it is to prevent tumor recurrence and metastasis in small doses, or to inhibit the proliferation, infiltration and induction of apoptosis in large doses.
American W+NMN rare ginsenosides have multiple effects: nourishing and nourishing the body, cultivating and consolidating the foundation, and improving immunity; Calm the nerves and help sleep, regulate insomnia, and relieve fatigue; Prevent cancer and fight cancer, promote tumor cell death, and reduce the risk of cancer; Rehabilitation assistance, promote postoperative recovery, reduce chemotherapy side effects, and improve quality of life.
We promise that the American W+NMN rare ginsenosides come from the primeval forest of Tongas, imported from the United States, and the quality is guaranteed. The products have been certified by international authorities with a real content of up to 20%, and have been certified by SGS's world-leading inspection, identification, testing and certification bodies.
Studies have shown that rare ginsenosides have four significant effects: directly inhibiting the proliferation, metastasis and spread of cancer cells; Adjuvant chemoradiotherapy and targeted therapy to alleviate toxic side effects and delay drug resistance; Take it after surgery to accelerate recovery, restore energy, and enhance immunity; Improve sleep, appetite, reduce cancer fatigue, and improve quality of life.
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References:
Wengong Wei, Baocheng Zhu, Haitao Xu, Lihui Si, Effect of ginsenoside Rh3 on inhibition of SKOV-3 proliferation in human ovarian cancer cells, China Maternal and Child Health, 2018, 33(4): 908-911
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