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The first antidepressant Chinese patent medicine in China - Shugan Jieyu Capsule

author:PSM Drug Shield Public Welfare

Because of the pressure of work and life,

Many people suffer from depression.

Depression is generally treated with medication

Shugan Jieyu Capsule is the first approved for use in China

Chinese patent medicine for the treatment of mild to moderate depressive disorder,

It fills the gap in the field of antidepressant medicine

What kind of depression is Shugan Jieyu suitable for?

How do I take it correctly?

Below, let's follow the editor to find out~

Liver soothing and depressant capsules

The first antidepressant Chinese patent medicine in China - Shugan Jieyu Capsule

Pharmaceutical components

Hypericum perforated leaves, eleutherococcos.

Dismantling of the group

Hypericum perforatifolia: medicinal properties are bitter and cold, return to the liver meridian, have the effect of soothing the liver and relieving depression, clearing heat and dampness, reducing swelling and clearing milk;

Acanthopanax senticosus: It is the rhizome or stem of the plant, which is beneficial to qi and spleen, and has the effect of tonifying the kidney and soothing the nerves.

The combination of two herbs, one is to relieve depression and the other to strengthen the spleen and soothe the nerves, the two are reasonably compatible, correct and replenish the deficiency, and hit the nail on the head, the effect is to relieve the liver and relieve depression, strengthen the spleen and calm the nerves.

Indications

Relieve liver and depression, strengthen the spleen and calm the nerves. It is suitable for mild and moderate unipolar depression and liver depression and spleen deficiency syndrome, with symptoms of depressed mood, delayed interest, difficulty falling asleep, early awakening, dreaminess, nervousness, irritability, lack of appetite, chest tightness, fatigue and weakness, excessive sweating, pain, white or greasy tongue, and thin pulse.

The first antidepressant Chinese patent medicine in China - Shugan Jieyu Capsule

What kind of depression can be used clinically?

1. mild-to-moderate depressive disorder (level of evidence: D; strength of recommendation: strong recommendation);

2. Post-stroke depression (mild to moderate depression) (level of evidence: D; strength of recommendation: strong);

3. Mild to moderate depressive disorder with sleep disturbance (level of evidence: D; strength of recommendation: strong recommendation);

4. Mild to moderate depressive disorder comorbid anxiety disorder or mild to moderate depressive disorder with anxiety state (level of evidence: D; strength of recommendation: strong recommendation);

5. Irritable bowel syndrome with mild to moderate depressive disorder (level of evidence: D; strength of recommendation: strong recommendation)

6. Other diseases (cardiovascular disease, type 2 diabetes, ischemic stroke) with mild to moderate senile depressive disorder (level of evidence: D; strength of recommendation: strong recommendation)

The first antidepressant Chinese patent medicine in China - Shugan Jieyu Capsule

Medication for special populations

1. Depressive disorder in adolescents with mild to moderate disease (13~18 years old) (level of evidence: C; strength of recommendation: strong recommendation);

2. Mild to moderate postpartum depressive disorder: Shugan Jieyu Capsule can be used alone or in combination with antidepressants (paroxetine, citalopram) (level of evidence: D; strength of recommendation: strong recommendation)

3. Mild to moderate perimenopausal depressive disorder: it is recommended that Shugan Jieyu Capsule can be used alone or in combination with chemical drugs (sertraline, escitalopram, paroxetine, haloperthiatine melitrexine tablets, tibolone) for the treatment of mild to moderate perimenopausal depressive disorder (level of evidence: D; strength of recommendation: strong recommendation);

4. Mild to moderate depressive disorder in old age (level of evidence: D; strength of recommendation: strong)

Dosage

Take orally. 2 capsules at a time, 2 times a day, once in the morning and once in the evening.

The course of treatment is 6 weeks.

Clinical advantages

1. Shugan Jieyu Capsule is a botanical drug, which is relatively safe, and there is no withdrawal reaction after stopping the drug;

2. When Shugan Jieyu Capsule is combined with other antidepressant chemical drugs, the dosage of chemical drugs can be reduced, the occurrence of adverse reactions can be reduced, the compliance of patients can be improved, and better efficacy can be achieved according to the specific conditions of patients.

Adverse effects

Occasionally, nausea and vomiting, dry mouth, headache, dizziness or syncope, insomnia, anorexia or anorexia, diarrhea, constipation, blurred vision, rash, palpitation, mildly elevated ALT.

Precautions

1. Patients with hepatic insufficiency should use with caution.

2. This product is easy to absorb moisture, and should be stored in a closed manner after taking the medicine, and pay attention to moisture-proof.

3. If the product changes its properties such as moisture absorption and agglomeration due to improper storage, do not continue to use it.

4. Keep out of reach and sight of children.

5. If you are using other medicines, please consult a physician or pharmacist before using this product.

Reviewer: Yang Yuanrong, Chief Pharmacist, Department of Pharmacy, Jingzhou Central Hospital, and Xiong Jianqun, Deputy Chief Pharmacist

Author: Liu Kaifei, Pharmacist-in-Charge, Department of Pharmacy, Jingzhou Central Hospital