In the context of National Cancer Week, we are focusing on an area of great concern – the treatment of liver cancer. For those patients with liver cancer that were once thought to be unresectable, conversion therapy is becoming a ray of hope for them to regain their lives.
Translational therapy, an innovative treatment model, is gradually breaking the limitations of traditional treatment and paving the way to recovery for liver cancer patients.
Recently, Wan Baishun, deputy chief physician of the Department of Hepatobiliary and Pancreatic Surgery of Henan Provincial Cancer Hospital, was a guest in the live broadcast room of the media "Dialogue with Famous Doctor Lin Xin" of the Medical Federation, and conducted a live broadcast with the theme of "Conversion Therapy: An Unresectable New Model of Liver Cancer Treatment", and discussed the related issues of liver cancer transformation therapy that netizens are concerned about.
Is there no cure for liver cancer in the middle and advanced stages? Don't give up, conversion therapy brings new life
China is one of the countries with a high incidence of liver cancer in the world. According to the World Health Organization, about 750,000 new cases of hepatocellular carcinoma occur every year, of which about 50% occur in China, seriously threatening the lives and health of mainland people.
The main reason is that the early symptoms of liver cancer are not obvious, and many patients are already in the middle and advanced stages when they are discovered, which also leads to poor treatment effect and poor prognosis of liver cancer.
In fact, with the continuous development of cancer treatment methods, the effect of liver cancer transformation therapy has been significantly improved.
Deputy Chief Physician Wan Baishun also said that more and more patients who were originally considered inoperable have been given the opportunity to be reoperated through conversion therapy, and even achieved long-term survival.
Conversion therapy makes the impossible possible
In the traditional concept, the treatment of liver cancer is often based on surgical resection, but many patients are judged to be unresectable due to the patient's general condition cannot withstand the surgical trauma, the liver function cannot be tolerated, and the remaining liver volume is insufficient. That's where conversion therapy comes in.
Deputy Chief Physician Wan Baishun introduced: "Conversion therapy is to increase the resectability of the initial unresectable liver cancer by lowering the tumor stage or increasing the remaining volume of the liver after surgery, so as to create conditions for surgical treatment. Transform the originally unresectable liver cancer into a resectable state, thereby improving the survival rate and quality of life of patients. ”
It is not only limited to traditional surgery, radiotherapy, chemotherapy and other means, but also integrates cutting-edge technologies such as targeted therapy and immunotherapy to form a diversified and personalized treatment plan. This treatment can not only improve the success rate of surgery, but also reduce the recurrence rate after surgery, thereby prolonging the survival of patients.
What are the common conversion treatment modalities for advanced liver cancer?
Conversion therapy mainly focuses on the two conditions of tumor and residual liver volume to determine the specific treatment method, in this regard, Deputy Chief Physician Wan Baishun also elaborated to us during the live broadcast:
1. Conversion therapy for tumors includes systemic therapy, local therapy and combination therapy, and local therapy includes hepatic arterial chemoembolization (TACE), hepatic arterial perfusion chemotherapy (HAIC), selective internal radiotherapy (SIRT), etc.;
2. Treatment of liver tissue includes increasing residual liver volume, improving liver function, and antiviral therapy.
During the live broadcast, Deputy Chief Physician Wan Baishun also talked about some cutting-edge technologies and methods of current liver cancer transformation therapy, such as the yttrium-90 microsphere, known as a "nuclear weapon", which is a treatment method that accurately treats liver tumors through hepatic arterial intervention through resin microspheres and radionuclide yttrium-90 ("90Y"), which has a strong tumor shrinkage effect, and can maintain a good quality of life for patients.
For patients with advanced liver cancer, although it is more difficult to treat, the emergence of conversion therapy provides them with new hope for survival. It is believed that with the progress of medicine, the treatment of liver malignant tumors will be more abundant and effective in the future, and the road of liver cancer patients will go better and further!
Wan Baishun
Department of Hepatobiliary and Pancreatic Surgery, Henan Provincial Cancer Hospital, Deputy Chief Physician
Member of the Biliary Department Professional Committee of Henan Anti-Cancer Association
He is a member of the Pancreas Professional Committee of Henan Anti-Cancer Association
Member of Hepatobiliary Branch of Henan Society of Clinical Oncology
Member of the Hepatobiliary and Pancreatic Prevention and Control Professional Committee of Henan Preventive Medicine Association
Majoring in clinical medicine (7 years) at the School of Medicine of Zhengzhou University, he is engaged in the diagnosis, treatment and basic research of liver, gallbladder and pancreatic tumors in Henan Provincial Cancer Hospital, especially proficient in the diagnosis and comprehensive treatment of liver tumors, biliary system tumors and pancreatic tumors
He has published 3 medical treatises and more than 10 papers
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