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Recently, the Liaoning Provincial Centralized Procurement Network for Drugs and Medical Consumables issued a notice on drug price reduction. It is reported that a total of 23 drugs have taken the initiative to adjust their prices, including cefoperazone sulbactam injections and other blockbuster varieties with terminal sales of more than 8 billion yuan in China's public medical institutions in 2022.
Source: Liaoning Provincial Drug and Medical Consumables Centralized Procurement Network
According to the content of the notice, all medical and health institutions in Liaoning Province will implement new online procurement prices for 23 drugs that have taken the initiative to reduce prices from today (April 17). The purchase transition period is set for reduced products, which is 1 week.
List of Drug Price Adjustments (Unit: RMB)
Source: Liaoning Province Drugs and Medical Consumables Centralized Procurement Network, Rice Network Finishing
Cefoperazone sulbactam is a compound preparation composed of cefoperazone (third-generation cephalosporin) and sulbactam (β-lactamase inhibitor), which has a strong synergistic antibacterial effect and is often used to treat infections caused by sensitive bacteria, upper / lower respiratory tract infections, upper / lower urinary tract infections, sepsis, etc.
Thanks to its good antibacterial and anti-inflammatory efficacy, cefoperazone sulbactam injection has expanded year by year in recent years, exceeding 8 billion yuan in 2022 and 35.67% year-on-year in the first half of 2023, making it the TOP2 variety of systemic anti-infective drugs.
Sales Trend of Terminal Cefoperazone Subactam Injection in China's Public Medical Institutions in Recent Years (Unit: 10,000 Yuan)
Source: Minenet's competitive landscape of drug terminals in China's public medical institutions
At present, there are 3 types of cefoperazone sulbactam injection approved for marketing in China, including cefoperazone sodium sulbactam sodium for injection, cefoperazone sodium sulbactam sodium for injection (2:1), cefoperazone sodium sulbactam sodium for injection sodium chloride injection, and the number of enterprises that have passed or are deemed to have passed the consistency evaluation are 16, 2 and 1 respectively. The injection has been included in the eighth batch of national procurement, and 10 companies including Kelun Pharmaceutical, Beite Pharmaceutical, Qilu Pharmaceutical, and Suzhou Erye Pharmaceutical have been successfully selected.
The selection of cefoperazone sulbactam injection in China
Source: Minenet Consistency Evaluation Progress Database
According to the bidding database of Minenet, in some provinces and cities in China in 2023, the unit price of cefoperazone sulbactam injection has risen sharply, reaching up to 436 yuan per piece. With the promotion of policies such as centralized procurement and "four same drugs", the price of the product has gradually recovered to the level before the sharp price increase, and the highest unit price in the country is about 82 yuan / branch.
The highest winning unit price of cefoperazone sulbactam injection in China (unit: yuan)
Source: Minenet Bidding Database
It is worth mentioning that Liaoning's list of drug price adjustments also includes: neostigmine methosulfate injection, phentolamine mesylate injection and other national shortage drugs/national clinically necessary drugs that are prone to shortage, as well as atorvastatin calcium tablets, amlodipine besylate tablets, mannitol injection and other star varieties with terminal sales of more than 1 billion yuan in China's public medical institutions in 2022, covering nervous system drugs, cardiovascular and cerebrovascular system drugs, Blood and hematopoietic system drugs and other treatment categories to meet the clinical needs of different patients.
Source: Minenet database, Liaoning Province Drugs and Medical Consumables Centralized Procurement Network
Note: The statistical scope of "Drug Terminal Competition Pattern of China's Public Medical Institutions" by Minenet is: China's urban public hospitals, county-level public hospitals, urban community centers and township health centers, excluding private hospitals, private clinics and village clinics, and the above sales are calculated based on the average retail price of products at the terminal. The statistics are as of April 17, if there is any omission, please correct!