Uncle Yang is a typical northerner, he loves to eat beef and mutton since he was a child, but in the past year or so, because of a lot of drinking, Uncle Yang's uric acid has risen rapidly, and the doctor specifically told him to eat less red meat. In winter, Uncle Yang is not greedy, especially when he meets a mutton restaurant on the road, the fragrance can give Uncle Yang a basin of saliva. But he could only grit his teeth and quickly walk away.
At present, the number of hyperuricemia patients in mainland China exceeds 180 million, which seems to be the "fourth highest" after hypertension, hyperglycemia and hyperlipidemia, but compared with the "three big brothers", many people do not have a deep understanding of uric acid.
So what exactly is uric acid, why is there such a product, and is it really impossible to eat mutton with high uric acid?
1. Can't you eat mutton with high uric acid?
When our body metabolizes purines, the final product is uric acid, under normal circumstances, the human body produces uric acid every day and excretes uric acid in a relatively balanced state.
So if we eat too much high-purine food, the metabolism of uric acid will increase, and the kidneys will not be able to completely metabolize these uric acids, and it will float with the blood, wherever it goes, they may be deposited in various organs of the body, causing a series of diseases.
For example, gout is the most common harm of high uric acid, which is because the uric acid that cannot be metabolized in the body will form urate crystals, once these crystals "go" to the joints and stop, deposition, gout will be produced, causing patients to have acute inflammation of cartilage and synovial tissues, resulting in gout.
Some patients also have typical symptoms such as swollen joints and pain, so gout is very painful.
Of course, what few people know is that the more serious harm of hyperuricemia is to damage the kidneys, because the uric acid in the blood is filtered from the glomeruli and renal tubules, so urate crystals are most likely to be deposited in the kidneys.
When the kidneys become dormant, stones form, small stones may be excreted in the urine, but large stones can block the urethra and renal tubules, causing serious diseases such as hydronephrosis, urinary tract infections and even hydronephrosis.
In addition, kidney stones and high uric acid will continuously stimulate the glomeruli to produce inflammation, thus forming chronic nephritis, which in turn affects the filtering function of the glomeruli, so that the kidney function will gradually decline, and even lead to chronic renal failure and uremia.
It can be seen that high uric acid is very dangerous, just like high blood pressure to control blood pressure, diabetes to control blood sugar, high uric acid to control uric acid. Red meat, such as mutton, is rich in nutrients and high in purines, so it is best for patients with high uric acid to eat less.
Second, if you don't want to hurt your kidneys, it's best not to eat these 3 foods!
The harm of too high uric acid is far from being as simple as joint pain, and it can most directly hurt the kidneys and even cause irreparable damage such as uremia, so in addition to controlling blood pressure, blood sugar, and blood lipids, it is also very important to control uric acid through diet.
1. Seafood + beer
This is a common combination for us to eat roadside stalls and feast with friends, but in fact, many seafood are medium and high purine foods, especially oysters and lobsters such as broth and shellfish.
Then when seafood meets beer, it is "adding insult to injury" and "adding fuel to the fire".
The ethanol in wine can directly stimulate the production of lactic acid and ketone, thereby inhibiting the excretion of uric acid, and ethanol can also accelerate the degradation of ATP, thereby increasing the rate of purine synthesis and increasing the production of uric acid. Therefore, wine can accelerate the rise of uric acid on the one hand, and block the body to prevent the excretion of uric acid, which is indeed easy to rise.
2. Puree and offal
Don't think that seafood raises uric acid, and other meats can be eaten unscrupulously. For example, many people like to stew chicken soup or pork bone soup to drink, but they don't know that many nutrients in meat are not water-soluble, even if they are cooked for a day or two, those vitamins and calcium are difficult to precipitate into the soup.
On the contrary, fats and purines will enter the broth from the meat, especially the purine itself is still a water-soluble substance, so the broth we drink is not too nutritious, and may also increase blood lipids and uric acid.
In addition, animal offal is also "rich in purines", such as liver, kidney, heart and brain, etc., so eating beef kidneys and sheep kidneys may not necessarily nourish the kidneys, and high purines may cause high uric acid and hurt the kidneys.
3. Drinks
Nowadays, more and more children will also develop high uric acid, which may be because the purines in the drink are not high, but they are rich in fructose.
After fructose enters the human body, it will be metabolized into uric acid, so after ingesting a large amount of fructose, it will significantly increase the level of uric acid in the body in a short period of time, and fructose may also inhibit the excretion of uric acid by the kidneys, which is similar to the harm of alcohol.
So this is also what we have to be careful about, drinks can not only cause high blood sugar, but even cause high uric acid, so usually for patients with high uric acid, just drink more water when thirsty.
3. What other misunderstandings do you know about high uric acid?
1. Patients with high uric acid do not drink water?
You must know that when we drink less water or sweat more, the blood volume in the body decreases, but the proportion of uric acid will rise, and if we drink less water, the amount of urine excretion will decrease, resulting in a decrease in uric acid excretion.
Therefore, drinking less water can easily cause an increase in uric acid levels, especially for patients with high uric acid, drinking less water is more likely to cause tophi and kidney damage, so it is recommended that friends with high uric acid must remember to drink more water.
2. Does gout have to be high in uric acid?
Does gout have to be high in uric acid?
As we mentioned above, gout is a complication of hyperuricemia, but the proportion of patients with gout who do not have high uric acid is as high as 49%. This is because when uric acid is too high, crystals may be precipitated in the blood and precipitated in the joints, but most of the uric acid in the blood at this time is precipitated, and the detected uric acid value may not be high.
In addition, gout itself is a violent inflammatory response, so a large number of inflammatory factors are produced in this process, such as interleukin 6, which stimulates the hypothalamus, releases cortisol to reduce uric acid levels, and interleukin 6 can promote the metabolism of uric acid.
Therefore, gout is produced by the patient in a state of high uric acid for a long time, but at the moment of gout, the patient's uric acid is not necessarily high.
3. When you have a gout attack, should you quickly lower uric acid?
It is not necessary to lower uric acid quickly after gout, because it is likely that the uric acid level itself is not high at this time, and direct uric acid lowering may cause hypouricemia.
And the rapid decrease in the level of uric acid may cause the urate crystals precipitated in the joints to fall off, which will continue to cause blood uric acid to be deposited in the joint cavity, so patients with acute gout attacks should control joint inflammation and pain, and usually reduce uric acid after 7~10 days after the symptoms are relieved.
bibliography
[1] Wei Haiyan, Lin Yifan, Yuan Shuxian. Evaluation and nutritional management of obesity complicated with hyperuricemia in children and adolescents [J]. Chinese Journal of Practical Pediatrics, 2023
[2] Wei Chunsheng. Current status and influencing factors of hyperuricemia in the population of Jinshui District, Zhengzhou [J]. Henan Medical Research, 2023
[3] Li Qiaoqiao, Deng Xiaoyuan, Liu Yao, et al. A systematic review of the detection rate and influencing factors of hyperuricemia among Chinese college students [J]. Chinese Convalescent Medicine, 2023
[4] Xie Liling, He Panpan, Qin Xianhui, et al. Research progress in the treatment of hyperuricemia [J]. Biomedical Translation, 2021
[5] Wu Peng, Wang Liang, Li Haitao, et al. Establishment of hyperuricemia model and research progress of uric acid-lowering drugs [J]. Chinese Journal of Pathophysiology, 2021.