What to do if a child under 8 years of age is diagnosed with mycoplasma pneumonia and azithromycin resistance
Recently, there are many such questions, and the simple answer is: if my child under 8 years old is diagnosed with mycoplasma pneumonia, I will still use azithromycin (the original drug) first, and if the symptoms do not improve after 3 days, I may switch to other macrolide drugs (such as clarithromycin or erythromycin), and if the symptoms still do not improve after 3 days, then switch to doxycycline; Of course, depending on the situation, it is also possible to switch to doxycycline directly after 3 days of azithromycin is not effective.
Some other practical points to refer to?
Opinion 1: If the symptoms of pneumonia are not severe, even if azithromycin is resistant, continued azithromycin can be cured.
Rationale: Self-limiting Mycoplasma pneumoniae infection (it's time to get better), and anti-inflammatory effects of macrolides.
Opinion 2: If the symptoms of pneumonia are not too severe, even if azithromycin is resistant, continue to use azithromycin, and if necessary, glucocorticoids can be cured.
Rationale: Anti-inflammatory effects of macrolides and glucocorticoids.
Opinion 3: Instead of azithromycin, use other macrolides, such as clarithromycin or erythromycin.
Reason: Effective in clinical use, and confirmed by relevant clinical studies.
Opinion 4: Instead of macrolides, directly use doxycycline in the new tetracycline antibacterial drugs.
Rationale: Azithromycin resistance is also likely to be resistant to other macrolides, macrolide-resistant Mycoplasma pneumoniae pneumoniae (MRMP) is already a global public health problem, and the mainland has the highest proportion of MRMP infections in the world. Tetracyclines, used during tooth growth and development (in the second and third trimesters of children under 8 years of age ➕), can affect tooth enamel development and cause permanent tooth discoloration. At the dosage recommended by current guidelines, short-term use of doxycycline "is unlikely to cause permanent tooth discoloration in young children" (sic, discretion).
Some people say, I have never used azithromycin, how can I be azithromycin resistant!? The resistance of mycoplasma and bacteria depends on whether the overall population in the region is overusing antibiotics, and individuals are not immune when the group is misusing antibiotics.
Each of us should reflect on every self-righteous medication we have used in the past.
