The famous "Confucian expert" actor and Ma Weijun died at the age of 67. Is it caused by heavy drinking for a long time?
The famous "Confucian expert" actor, Ma Weijun, died young
According to media reports, the well-known actor and Ma Weijun tragically passed away due to illness on September 13, 2023.
Speaking of the name Ma Weijun, many people may feel strange and do not match the well-known actors.
However, the image of the "Demon King Officer" he played in many TV series is almost unknown to anyone.
Yes, Ma Weijun is one of the few "Japanese pro player" actors who have been active on film and television screens for a long time.
According to public information, Ma Weijun was born in 1956 and died at the age of 67. In today's world, where life expectancy has increased significantly, he died young.
People told insiders that Ma Weijun has always been in good health, and they met on the set of Hengdian not long ago.
As a well-known professional player, the actor must have a very good income, which means that his living conditions are much better than ordinary people.
If the average life expectancy today had increased significantly, Ma Weijun would have died at least 20 years earlier.
What are the disadvantages of drinking heavily for a long time?
According to public information, Ma Weijun died of throat cancer.
So what is the reason that the actor, a well-known person with good health and excellent living conditions, suffered from throat cancer and died at least 20 years early?
Epidemiological investigations have shown that men and advanced age are unchangeable risk factors for laryngeal cancer. That is, laryngeal cancer mainly occurs in men over the age of 50 and increases with age.
Among the modifiable risk factors for laryngeal cancer, the most important are long-term smoking and long-term alcohol consumption; This is followed by gastroesophageal reflux (acid reflux), occupational exposure, and human papillomavirus infection.
According to GHDx, a global health big data platform affiliated with the University of Washington's Institute for Health Metrics and Evaluation, long-term smoking and alcohol consumption account for about 60 percent and 30 percent of all throat cancer deaths, respectively.
In other words, if someone dies of throat cancer, it is almost always due to long-term smoking or drinking.
According to people, in the circle, Ma Weijun does not seem to smoke, but he likes to eat and drink at parties, especially strong drinks.
Ma Weijun always seemed particularly generous and heroic at the wine table.
Therefore, according to general medical principles, Ma Weijun's throat cancer is most likely caused by long-term heavy drinking.
From a medical point of view, laryngeal cancer is one of the cancers associated with smoking or drinking.
One of the distinguishing features of tobacco and alcohol that causes cancer is that "the moon is the first to approach water and buildings", that is, cancer most often occurs at the site of direct exposure.
Among the 7 types of alcohol-related cancers for which there is strong evidence, in addition to female breast cancer, oropharyngeal cancer, colorectal cancer, esophageal cancer, laryngeal cancer, and liver cancer (the main metabolic site of alcohol) are all closely related to alcohol. ”。 Importantly, East Asians, including Chinese, are particularly vulnerable to the harmful effects of alcohol and are more likely to develop alcohol-related cancers.
This is because, due to genetic mutations, about one-third of "yellow people" have very low activity of acetaldehyde dehydrogenase, a key liver enzyme responsible for alcohol metabolism.
In the general population, acetaldehyde dehydrogenase is extremely active. Alcohol is further oxidized to harmless acetic acid immediately after being broken down into acetaldehyde by alcohol dehydrogenase in the liver. Even if you drink a lot of alcohol, acetaldehyde is almost undetectable in the blood.
However, in some East Asians, genetic mutations lead to inactivation of acetaldehyde dehydrogenase. After these people drink alcohol, acetaldehyde breaks down very slowly into acetic acid, which causes acetaldehyde to accumulate in the body.
An important physiological role of acetaldehyde is to dilate blood vessels, especially skin blood vessels.
Due to the dilation of blood vessels in the skin, especially the face, these people tend to blush after drinking. This phenomenon is also known as "Asian red".
Depending on the combination of allele variants, the degree of inactivation of acetaldehyde dehydrogenase encoded is different, and the rate and degree of post-alcohol flushing are also different.
Those who drink only a small amount of alcohol and immediately blush noticeably, the so-called "wine flush", have almost complete inactivation of acetaldehyde dehydrogenase in the body.
We know that aldehydes are highly biologically active toxic substances, especially to the DNA of biological genetic material.
Studies have shown that the main mechanism of alcohol carcinogenesis is DNA damage caused by the alcohol metabolite acetaldehyde.
Therefore, people who "blush when they encounter alcohol" will have worse health if they drink a lot of alcohol, and they are particularly vulnerable to alcohol-related cancers, including throat cancer.
Judging from the photos on the wine table, Ma Weijun is the person who is most prone to alcohol poisoning and "blushing when he touches wine".
This also suggests that Ma Weijun's throat cancer is likely caused by long-term, heavy drinking.
Long-term heavy drinking reduces life expectancy by nearly 30 years
Most people think that smoking is extremely harmful; Drinking alcohol is much less harmful to health.
Actually no.
In terms of premature death, long-term heavy drinking is more life-saving than long-term heavy smoking.
The reason is simple.
The main cause of death from smoking is chronic diseases caused by long-term smoking; The causes of death from long-term heavy drinking include acute injuries and illnesses caused by excessive alcohol consumption and chronic diseases caused by excessive alcohol consumption.
According to the latest (most recent) report released by the CDC on deaths from excessive alcohol consumption in the United States,
Between 2011 and 2015, an average of 93,296 people died each year in the United States from excessive alcohol consumption, an average of 255 deaths per day. Among them, the number of deaths due to injuries caused by acute illness and excessive alcohol consumption (45.2%) was roughly the same as the number of deaths caused by chronic diseases (54.7%).
Deaths from alcohol-related cancers, including throat cancer, are an important part of chronic disease deaths from excessive alcohol consumption. After statistical analysis, the cumulative potential life expectancy (YPLL) due to excessive drinking in the United States over the past 5 years is 2.7 million years, with an average of 29 years per death.
In other words, in Mandarin
People who drink heavily for a long time have a shorter life expectancy or die on average 29 years earlier.
。
As I showed before, someone once calculated that the average life expectancy of all long-term drinkers in the United States was reduced by 23.1 years, and the average life expectancy of drinking 1 glass of wine (containing 14 grams of pure alcohol) was reduced by 6.6 hours. It is basically consistent with the epidemiological data published by the CDC.
In other words, there is ample evidence that people who drink heavily for a long time shorten their lives by an average of 20 to 30 years.
Ma Weijun caused throat cancer caused by long-term consumption of high concentrations of spirits in the above range, and died at least 20 years early.
Only published in the headline number, all other platforms are porters
The picture comes from the Internet, invaded and deleted.
Original is not easy, welcome to forward!
What is your opinion on this? Welcome to leave a comment in the comment area!